Iodides

solute carrier family 5 member 5 ; Homo sapiens







185 Article(s)
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1 34520744 Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. 2022 Mar 17 1
2 34806438 Brief Report: A Novel Sodium/Iodide Symporter Mutation, S356F, Causing Congenital Hypothyroidism. 2022 Feb 2
3 34922208 Small activating RNA-activated NIS gene promotes 131I uptake and inhibits thyroid cancer via AMPK/mTOR pathway. 2022 Jan 7
4 35438852 Clinical characteristics and genetics analysis for the ITD of congenital hypothyroidism. 2022 Jun 27 2
5 35600585 Silent but Not Harmless: A Synonymous SLC5A5 Gene Variant Leading to Dyshormonogenic Congenital Hypothyroidism. 2022 1
6 33002449 Expression of the sodium iodide symporter (NIS) in reproductive and neural tissues of teleost fish. 2021 Jan 1 2
7 33779310 The Iodide Transport Defect-Causing Y348D Mutation in the Na+/I- Symporter Renders the Protein Intrinsically Inactive and Impairs Its Targeting to the Plasma Membrane. 2021 Aug 1
8 33912899 A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis. 2021 Jun 16 2
9 33974556 Na+/I- symporter expression, function, and regulation in non-thyroidal tissues and impact on thyroid cancer therapy. 2021 Sep 3 2
10 34196428 The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane. 2021 Aug 4
11 34387194 The complex regulation of NIS expression and activity in thyroid and extrathyroidal tissues. 2021 Sep 3 4
12 34514854 Impact of the Mutational Landscape of the Sodium/Iodide Symporter in Congenital Hypothyroidism. 2021 Dec 2
13 34771624 Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer. 2021 Oct 30 1
14 32049985 TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells. 2020 4
15 32084174 Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS). 2020 1
16 33055303 Re-visiting autoimmunity to sodium-iodide symporter and pendrin in thyroid disease. 2020 Dec 1
17 33291224 Species D Adenoviruses as Oncolytic Viral Vectors. 2020 Dec 6 1
18 30191346 Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer. 2019 May 1
19 31115276 Novel Sodium/Iodide Symporter Compound Heterozygous Pathogenic Variants Causing Dyshormonogenic Congenital Hypothyroidism. 2019 Jul 1
20 31533238 Radioiodine-Refractory Thyroid Cancer: Molecular Basis of Redifferentiation Therapies, Management, and Novel Therapies. 2019 Sep 17 1
21 29242405 Digitalislike Compounds Restore hNIS Expression and Iodide Uptake Capacity in Anaplastic Thyroid Cancer. 2018 May 1
22 29467904 Human sodium iodide transporter gene-mediated imaging and therapy of mouse glioma, comparison between 188Re and 131I. 2018 Mar 1
23 29631680 An investigation of NIS expression in gastric tissue of obese individuals. 2018 Mar 31 2
24 30217930 A Nonpump Function of Sodium Iodide Symporter in Thyroid Cancer via Cross-talk with PTEN Signaling. 2018 Nov 1 2
25 30595693 The Role of the NIS (SLC5A5) Gene in Papillary Thyroid Cancer: A Systematic Review. 2018 3
26 28117294 The Thyroid Na+/I- Symporter: Molecular Characterization and Genomic Regulation. 2017 Feb 9 2
27 28192058 The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications. 2017 Feb 10 2
28 28974598 Molecular radiotheragnostics in thyroid disease. 2017 Oct 1
29 31966449 Targeting of pertechnetate imaging of HepG2 hepatocellular carcinoma through the transduction of the survivin promoter controls the sodium iodide symporter. 2017 1
30 27614840 Sterol regulatory element-binding proteins are regulators of the sodium/iodide symporter in mammary epithelial cells. 2016 Nov 1
31 28036366 Longitudinal Assessment of Lung Cancer Progression in Mice Using the Sodium Iodide Symporter Reporter Gene and SPECT/CT Imaging. 2016 1
32 25410753 Glial fibrillary acidic protein promoters direct adenovirus early 1A gene and human telomerase reverse transcriptase promoters direct sodium iodide symporter expression for malignant glioma radioiodine therapy. 2015 Jan 1
33 25615643 Experimental study of nasopharyngeal carcinoma radionuclide imaging and therapy using transferred human sodium/iodide symporter gene. 2015 1
34 26204134 Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency. 2015 Oct 2
35 26282166 The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis. 2015 Oct 1 2
36 26599396 Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake. 2015 1
37 23988430 The sodium/iodide symporter: state of the art of its molecular characterization. 2014 Jan 2
38 24369144 Radioiodine therapy for castration-resistant prostate cancer following prostate-specific membrane antigen promoter-mediated transfer of the human sodium iodide symporter. 2014 Jan-Feb 3
39 24708099 NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer. 2014 Jul 2
40 24884806 Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer. 2014 Apr 30 1
41 24888603 Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter. 2014 Jun 3 1
42 25309780 Radioiodine therapy in differentiated thyroid cancer: the first targeted therapy in oncology. 2014 Sep 1
43 23117572 Sodium/iodide symporter is expressed in the majority of seminomas and embryonal testicular carcinomas. 2013 Feb 2
44 23404856 MEK inhibition leads to lysosome-mediated Na+/I- symporter protein degradation in human breast cancer cells. 2013 Apr 2
45 23420532 The glial fibrillary acidic protein promoter directs sodium/iodide symporter gene expression for radioiodine therapy of malignant glioma. 2013 Feb 2
46 23441638 Modulation of sodium/iodide symporter expression in the salivary gland. 2013 Aug 1
47 23471296 TRPM7 is regulated by halides through its kinase domain. 2013 Aug 2
48 23857380 Na+/I- symporter and type 3 iodothyronine deiodinase gene expression in amniotic membrane and placenta and its relationship to maternal thyroid hormones. 2013 Sep 1
49 24052075 The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells. 2013 Sep 19 2
50 24193032 EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene. 2013 Nov 5 1