| 51 |
18162191 | Fecal collection, ambient preservation, and DNA extraction for PCR amplification of bacterial and human markers from human feces. | 2008 Feb |
1 |
| 52 |
18182479 | Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibition. | 2008 Apr |
1 |
| 53 |
18400109 | Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. | 2008 Apr 9 |
1 |
| 54 |
17334909 | Human reduced folate carrier: translation of basic biology to cancer etiology and therapy. | 2007 Mar |
2 |
| 55 |
17404734 | Transcription regulatory polymorphism -43T>C in the 5'-flanking region of SLC19A1 gene could affect rheumatoid arthritis patient response to methotrexate therapy. | 2007 Sep |
2 |
| 56 |
17475669 | Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans. | 2007 Aug |
2 |
| 57 |
16368880 | Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles: transcriptional silencing, inactivating mutations, and allele loss. | 2006 Apr 15 |
2 |
| 58 |
16371350 | Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. | 2006 Feb 24 |
1 |
| 59 |
16428507 | Transcriptional regulation of the human reduced folate carrier in childhood acute lymphoblastic leukemia cells. | 2006 Jan 15 |
2 |
| 60 |
16505119 | The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line. | 2006 Feb |
1 |
| 61 |
16585211 | 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism. | 2006 Apr 1 |
1 |
| 62 |
16900951 | Comparison of folic acid uptake characteristics by human placental choriocarcinoma cells at acidic and physiological pH. | 2006 Feb |
1 |
| 63 |
16962770 | Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population. | 2006 Dec |
2 |
| 64 |
15385270 | Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function. | 2005 Jan |
4 |
| 65 |
15630450 | Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. | 2005 Jan |
1 |
| 66 |
15871139 | Biotin-responsive basal ganglia disease maps to 2q36.3 and is due to mutations in SLC19A3. | 2005 Jul |
1 |
| 67 |
15939798 | The reduced folate carrier gene is a novel selectable marker for recombinant protein overexpression. | 2005 Sep |
4 |
| 68 |
16041371 | Karyotypic abnormalities create discordance of germline genotype and cancer cell phenotypes. | 2005 Aug |
1 |
| 69 |
16109384 | The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells. | 2005 Aug 30 |
3 |
| 70 |
14551190 | Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not promoter methylation. | 2004 Jan 2 |
1 |
| 71 |
14602046 | Analysis of the membrane topology for transmembrane domains 7-12 of the human reduced folate carrier by scanning cysteine accessibility methods. | 2004 Feb 15 |
2 |
| 72 |
14998787 | Mechanism and regulation of folate uptake by human pancreatic epithelial MIA PaCa-2 cells. | 2004 Jul |
3 |
| 73 |
15297414 | Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start. | 2004 Aug 1 |
1 |
| 74 |
15337749 | Restoration of transport activity by co-expression of human reduced folate carrier half-molecules in transport-impaired K562 cells: localization of a substrate binding domain to transmembrane domains 7-12. | 2004 Nov 5 |
2 |
| 75 |
15340044 | Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene. | 2004 Dec |
1 |
| 76 |
15564880 | Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis. | 2004 Nov |
1 |
| 77 |
12749765 | Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods. | 2003 Aug 15 |
3 |
| 78 |
12887734 | Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart. | 2003 Jul 29 |
1 |
| 79 |
14584080 | Reduced folate carrier protein expression in osteosarcoma: implications for the prediction of tumor chemosensitivity. | 2003 Nov 1 |
1 |
| 80 |
15068242 | Increased expression of human reduced folate carrier in fetal Down syndrome brain. | 2003 |
1 |
| 81 |
12139489 | Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines. | 2002 Nov 1 |
1 |
| 82 |
12175915 | Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis. | 2002 Aug 31 |
2 |
| 83 |
12228234 | The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism. | 2002 Nov 15 |
2 |
| 84 |
12454742 | Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells. | 2002 Dec |
1 |
| 85 |
11106643 | Repression of human reduced folate carrier gene expression by wild type p53. | 2001 Mar 23 |
1 |
| 86 |
11280750 | Localization of a human reduced folate carrier protein in the mitochondrial as well as the cell membrane of leukemia cells. | 2001 Mar 1 |
1 |
| 87 |
11290853 | Reduced folate carrier: tissue distribution and effects of chronic ethanol intake in the micropig. | 2001 Mar |
2 |
| 88 |
11705857 | Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers. | 2001 Nov |
1 |
| 89 |
11731220 | SLC19A3 encodes a second thiamine transporter ThTr2. | 2001 Nov 29 |
1 |
| 90 |
10677373 | Mutations in the reduced-folate carrier affect protein localization and stability. | 2000 Mar 1 |
2 |
| 91 |
10100715 | Mechanisms of methotrexate resistance in osteosarcoma. | 1999 Mar |
1 |
| 92 |
10391223 | Mutations in a new gene encoding a thiamine transporter cause thiamine-responsive megaloblastic anaemia syndrome. | 1999 Jul |
1 |
| 93 |
9426700 | Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells. | 1998 Jan 5 |
1 |
| 94 |
9037252 | Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity. | 1997 Jan 24 |
1 |
| 95 |
9041240 | Human intestinal folate transport: cloning, expression, and distribution of complementary RNA. | 1997 Mar |
2 |
| 96 |
9310238 | Confocal microscopy visualization of antifolate uptake by the reduced folate carrier in human leukaemic cells. | 1997 |
1 |
| 97 |
8276792 | A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. | 1994 Jan 7 |
2 |