Cocaine

opioid receptor kappa 1 ; Homo sapiens







27 Article(s)
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1 34843875 Analyses of polymorphisms of intron 2 of OPRK1 (kappa-opioid receptor gene) in association with opioid and cocaine dependence diagnoses in an African-American population. 2022 Jan 18 3
2 31463605 The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research. 2020 4
3 31026862 Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study. 2019 Sep 6
4 28857070 Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence. 2018 Mar 1
5 30076211 Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion. 2018 Sep 12 1
6 29056156 Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction. 2017 2
7 25581305 Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys. 2016 Mar 1
8 24484983 Mixed κ/μ partial opioid agonists as potential treatments for cocaine dependence. 2014 1
9 23438330 Orvinols with mixed kappa/mu opioid receptor agonist activity. 2013 Apr 25 1
10 23962922 A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving, limbic brain activation and cocaine relapse risk. 2013 Aug 20 2
11 23995774 The κ-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial. 2013 Dec 3
12 22709632 κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction. 2012 Oct 1
13 18923396 A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain. 2009 Apr 1
14 18178175 The kappa-opioid receptor antagonist nor-BNI inhibits cocaine and amphetamine, but not cannabinoid (WIN 52212-2), abstinence-induced withdrawal in planarians: an instance of 'pharmacologic congruence'. 2008 Feb 8 2
15 18639235 The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward. 2008 Dec 1 2
16 15988468 Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity? 2005 Dec 1
17 14757849 Kappa-opioid receptor ligands inhibit cocaine-induced HIV-1 expression in microglial cells. 2004 May 6
18 15608558 Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. 2004 Dec 2
19 12112394 Chronic cocaine increases kappa-opioid receptor density: lack of effect by selective dopamine uptake inhibitors. 2002 Sep 1 1
20 11526958 Effect of the kappa-opioid receptor agonist, U69593, on reinstatement of extinguished amphetamine self-administration behavior. 2001 Apr 2
21 9862779 Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions. 1999 Jan 1
22 10415709 Modulation of cocaine-induced sensitization by kappa-opioid receptor agonists. Role of the nucleus accumbens and medial prefrontal cortex. 1999 Jun 29 1
23 10435406 U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking. 1999 Jun 3
24 9218269 Sensitization to the behavioral effects of cocaine: modulation by dynorphin and kappa-opioid receptor agonists. 1997 Jul 1
25 8943583 Cocaine, dopamine and the endogenous opioid system. 1996 1
26 7827335 U-69593 prevents cocaine sensitization by normalizing basal accumbens dopamine. 1994 Sep 8 2
27 1328733 The role of mu- and kappa-opioid receptors in cocaine-induced conditioned place preference. 1992 Apr 2