polyglutamine

androgen receptor ; Homo sapiens







221 Article(s)
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51 26428534 Mitochondrial implications in bulbospinal muscular atrophy (Kennedy disease). 2015 4
52 26453288 Identification of novel polyglutamine-expanded aggregation species in spinal and bulbar muscular atrophy. 2015 Dec 2 4
53 26673324 Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA. 2015 Dec 15 2
54 28031874 Trinucleotide repeats and protein folding and disease: the perspective from studies with the androgen receptor. 2015 Sep 1
55 29124176 The polyglutamine-expanded androgen receptor has increased DNA binding and reduced transcriptional activity. 2015 Sep 4
56 23656576 Spinal and bulbar muscular atrophy: pathogenesis and clinical management. 2014 Jan 1
57 24742193 Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy. 2014 Jul 2
58 24742458 Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy. 2014 Apr 16 2
59 24925468 Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients. 2014 Oct 1
60 25108912 Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. 2014 Sep 2
61 25157508 CLEARance wars: PolyQ strikes back. 2014 Sep 1
62 25182772 Analysis of the conformation of the androgen receptor in spinal bulbar muscular atrophy by atomic force microscopy. 2014 2
63 25309920 From pathways to targets: understanding the mechanisms behind polyglutamine disease. 2014 2
64 25398798 CAG-repeats in the androgen receptor gene relate with plasma androgen levels in the Bouvier Des Flandres. 2014 Nov-Dec 2
65 25449082 [Molecular diagnosis for a patient with Kennedy disease]. 2014 Dec 1
66 23420040 New routes to therapy for spinal and bulbar muscular atrophy. 2013 Jul 6
67 23467468 Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility. 2013 Feb 2
68 23644820 Androgen-dependent impairment of myogenesis in spinal and bulbar muscular atrophy. 2013 Jul 6
69 23719921 Cell biological approaches to investigate polyglutamine-expanded AR metabolism. 2013 7
70 23810450 Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy. 2013 Nov 4
71 21940984 Androgen receptor gene polymorphisms and the fat-bone axis in young men and women. 2012 Jul-Aug 1
72 22158719 Molecular pathophysiology and disease-modifying therapies for spinal and bulbar muscular atrophy. 2012 Apr 2
73 22609045 Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA). 2012 Dec 9
74 22660636 Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2. 2012 Jul 4
75 22720173 Current status of treatment of spinal and bulbar muscular atrophy. 2012 1
76 22796525 Polyglutamined expanded androgen receptor interacts with chaperonin CCT. 2012 Nov 1
77 23024039 Role of androgen receptor polyQ chain elongation in Kennedy's disease and use of natural osmolytes as potential therapeutic targets. 2012 Nov 5
78 23196565 [Anti-androgen therapy for spinal and bulbar muscular atrophy (SBMA)]. 2012 4
79 19617210 Androgen receptor gene polymorphisms lean mass and performance in young men. 2011 Feb 2
80 21216197 Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial. 2011 Feb 2
81 21284948 Role of the androgen receptor CAG repeat polymorphism in prostate cancer, and spinal and bulbar muscular atrophy. 2011 Mar 28 2
82 21664238 Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells. 2011 Aug 6 3
83 21712734 Severity of coronary artery disease in postmenopausal women: association with the androgen receptor gene (CAG)n repeat polymorphism. 2011 Nov 1
84 21745497 Neurotoxic effects of androgens in spinal and bulbar muscular atrophy. 2011 Oct 2
85 21949845 ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract. 2011 6
86 22131404 SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA. 2011 Nov 30 16
87 19833203 Involvement of three glutamine tracts in human androgen receptor transactivation. 2010 Jan 6
88 20140226 F-actin binding regions on the androgen receptor and huntingtin increase aggregation and alter aggregate characteristics. 2010 Feb 4 1
89 20410122 Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy. 2010 Apr 21 2
90 20691641 Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial. 2010 Sep 1
91 20826791 An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy. 2010 Nov 12 4
92 20846673 Perspectives of Kennedy's disease. 2010 Nov 15 1
93 18289734 Specific N-terminal mutations in the human androgen receptor induce cytotoxicity. 2009 Nov 3
94 18824496 Mitochondrial abnormalities in spinal and bulbar muscular atrophy. 2009 Jan 1 3
95 18840639 Increased estrogen rather than decreased androgen action is associated with longer androgen receptor CAG repeats. 2009 Jan 1
96 19095061 Short alleles of both GGN and CAG repeats at the exon-1 of the androgen receptor gene are associated to increased PSA staining and a higher Gleason score in human prostatic cancer. 2009 Jan 2
97 19100835 Androgens inhibit androgen receptor promoter activation in motor neurons. 2009 Mar 6
98 19168451 Length of androgen receptor-CAG repeats in fertile and infertile Egyptian men. 2009 Jul-Aug 1
99 19228953 Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk. 2009 Feb 18 3
100 19231085 Polymorphism of the long polyglutamine tract in the human androgen receptor influences craving of men in alcohol withdrawal. 2009 Aug 1