| 1 |
35100927 | Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer. | 2022 Jul |
5 |
| 2 |
35209071 | Inhibitory Effect of Ursolic Acid on the Migration and Invasion of Doxorubicin-Resistant Breast Cancer. | 2022 Feb 14 |
1 |
| 3 |
35541910 | Downregulation of MTAP promotes Tumor Growth and Metastasis by regulating ODC Activity in Breast Cancer. | 2022 |
2 |
| 4 |
33452997 | Rice yellow stunt virus activates polyamine biosynthesis to promote viral propagation in insect vectors by disrupting ornithine decarboxylase antienzyme function. | 2021 Sep |
2 |
| 5 |
33579942 | Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas. | 2021 Feb 12 |
4 |
| 6 |
33621898 | Radiosynthesis and evaluation of N5-(2-18F-fluoropropanyl) ornithine as a potential agent for tumor PET imaging. | 2021 Mar-Apr |
1 |
| 7 |
33934471 | Capryloyl glycine and soy isoflavonoids in hypertrichosis: An experimental and placebo-controlled clinical study. | 2021 Apr |
2 |
| 8 |
34029478 | Refractive Index Sensing for Measuring Single Cell Growth. | 2021 Jun 22 |
2 |
| 9 |
34055746 | The First Insight Into the Supramolecular System of D,L-α-Difluoromethylornithine: A New Antiviral Perspective. | 2021 |
3 |
| 10 |
34067619 | Characterising the Response of Human Breast Cancer Cells to Polyamine Modulation. | 2021 May 17 |
2 |
| 11 |
34129075 | Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma. | 2021 Oct |
3 |
| 12 |
34252566 | The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors. | 2021 Sep |
4 |
| 13 |
34282722 | Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease. | 2021 Jul 20 |
1 |
| 14 |
34376808 | Ornithine decarboxylase (ODC1) gene variant (rs2302615) is associated with gastric cancer independently of Helicobacter pylori CagA serostatus. | 2021 Oct |
10 |
| 15 |
34529197 | Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase. | 2021 Nov |
2 |
| 16 |
34638596 | Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer. | 2021 Sep 23 |
5 |
| 17 |
31793679 | Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer. | 2020 Feb |
2 |
| 18 |
32139506 | Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy. | 2020 May 8 |
3 |
| 19 |
32373551 | Difluoromethylornithine, a Decarboxylase 1 Inhibitor, Suppresses Hepatitis B Virus Replication by Reducing HBc Protein Levels. | 2020 |
2 |
| 20 |
32697811 | Anti-GD2 induced allodynia in rats can be reduced by pretreatment with DFMO. | 2020 |
2 |
| 21 |
32984708 | Chiral Chromatographic Isolation on Milligram Scale of the Human African Trypanosomiasis Treatment d- and l-Eflornithine. | 2020 Sep 22 |
1 |
| 22 |
33216820 | Effect of eflornithine on mutation frequency in temozolomide-treated U87MG cells. | 2020 Nov 3 |
1 |
| 23 |
33292222 | Polyamines and related signaling pathways in cancer. | 2020 Nov 5 |
1 |
| 24 |
29436980 | Virtual screening of natural inhibitors targeting ornithine decarboxylase with pharmacophore scaffolding of DFMO and validation by molecular dynamics simulation studies. | 2019 Feb |
4 |
| 25 |
29452772 | Metabolic and Lipidomic Reprogramming in Renal Cell Carcinoma Subtypes Reflects Regions of Tumor Origin. | 2019 Jul |
1 |
| 26 |
30355744 | A Modified Tripeptide Motif of RS1 (RSC1A1) Down-Regulates Exocytotic Pathways of Human Na+-d-glucose Cotransporters SGLT1, SGLT2, and Glucose Sensor SGLT3 in the Presence of Glucose. | 2019 Jan |
2 |
| 27 |
30642111 | Inhibition of Polyamine Biosynthesis Reverses Ca2+ Channel Remodeling in Colon Cancer Cells. | 2019 Jan 13 |
4 |
| 28 |
30871110 | Extracellular Spermine Activates DNA Methyltransferase 3A and 3B. | 2019 Mar 12 |
1 |
| 29 |
31249027 | Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation. | 2019 Jul 24 |
6 |
| 30 |
31765147 | Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives. | 2019 Dec 26 |
2 |
| 31 |
32256343 | Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells. | 2019 |
1 |
| 32 |
29378419 | Clinical importance of eflornithine (α-difluoromethylornithine) for the treatment of malignant gliomas. | 2018 Apr |
2 |
| 33 |
29419804 | Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases. | 2018 Feb 8 |
8 |
| 34 |
29626790 | pH gradient-liquid chromatography tandem mass spectrometric assay for determination of underivatized polyamines in cancer cells. | 2018 May 15 |
2 |
| 35 |
30066894 | Inhibition of ornithine decarboxylase 1 facilitates pegylated arginase treatment in lung adenocarcinoma xenograft models. | 2018 Oct |
3 |
| 36 |
30115881 | Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy. | 2018 Aug 16 |
4 |
| 37 |
30138353 | Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. | 2018 |
4 |
| 38 |
30239107 | Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features. | 2018 Dec |
1 |
| 39 |
30262852 | Maintenance DFMO Increases Survival in High Risk Neuroblastoma. | 2018 Sep 27 |
2 |
| 40 |
30404920 | Polyamine synthesis as a target of MYC oncogenes. | 2018 Nov 30 |
2 |
| 41 |
30475806 | Insights into antitrypanosomal drug mode-of-action from cytology-based profiling. | 2018 Nov |
1 |
| 42 |
28125906 | Difluoromethylornithine in cancer: new advances. | 2017 Apr |
3 |
| 43 |
28346093 | A Label-Free Continuous Fluorescence-Based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor. | 2017 Aug |
2 |
| 44 |
28679527 | Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei. | 2017 Oct |
1 |
| 45 |
29215586 | Investigation of Polyamine Metabolism and Homeostasis in Pancreatic Cancers. | 2017 Dec 7 |
1 |
| 46 |
29872701 | Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression. | 2017 |
1 |
| 47 |
27001865 | Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation. | 2016 May 15 |
1 |
| 48 |
27480131 | Efficacy and safety of eflornithine (CPP-1X)/sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and rationale of a randomized, double-blind, Phase III trial. | 2016 Aug 2 |
4 |
| 49 |
27535047 | Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses. | 2016 Nov 1 |
6 |
| 50 |
29897188 | [Exposure of human hepatoma cells to nitrite and ammonia promotes invasive activity through activation of ROS/ODC pathway]. | 2016 Jul |
2 |