Vinblastine

Jun proto-oncogene, AP-1 transcription factor subunit ; Homo sapiens







12 Article(s)
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1 24088727 Involvement of AP-1 and NF-κB in the up-regulation of P-gp in vinblastine resistant Caco-2 cells. 2014 3
2 19161984 p21 functions in a post-mitotic block checkpoint in the apoptotic response to vinblastine. 2009 Mar 6 1
3 18094076 Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1. 2008 Jan 11
4 18341588 Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. 2008 Apr 5
5 17126817 Inducible overexpression of c-Jun in MCF7 cells causes resistance to vinblastine via inhibition of drug-induced apoptosis and senescence at a step subsequent to mitotic arrest. 2007 Feb 15 8
6 16111654 Role of c-Jun in cellular sensitivity to the microtubule inhibitor vinblastine. 2005 Oct 7 6
7 12907245 The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. 2003 Aug 1 1
8 12221076 Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. 2002 Nov 15 1
9 11389075 The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine. 2001 Jun 1 4
10 11585055 AP-1 activation and altered AP-1 composition in association with increased phosphorylation and expression of specific Jun and Fos family proteins induced by vinblastine in KB-3 cells. 2001 Sep 1 1
11 10913135 Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade. 2000 Sep 29 2
12 9478937 Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways. 1998 Feb 27 1