Tetradecanoylphorbol Acetate

Jun proto-oncogene, AP-1 transcription factor subunit ; Homo sapiens







233 Article(s)
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1 33307168 PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression. 2021 Feb 1 1
2 34512147 The role of N-cadherin/c-Jun/NDRG1 axis in the progression of prostate cancer. 2021 2
3 31194000 Forskolin and Phorbol 12-myristate 13-acetate modulates the expression pattern of AP-1 factors and cell cycle regulators in estrogen-responsive MCF-7 cells. 2019 Jun 1
4 29660338 Different molecular mechanisms of HTLV-1 and HIV LTR activation by TPA. 2018 Jun 7 2
5 28098862 Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in human ovarian carcinoma cells. 2017 Mar 1
6 28970848 Crotonis Fructus Extract Inhibits 12-O-Tetradecanoylphorbol-13-Acetate-Induced Expression of Matrix Metalloproteinase-9 via the Activator Protein-1 Pathway in MCF-7 Cells. 2017 Sep 3
7 27708396 ERK/c-Jun Recruits Tet1 to Induce Zta Expression and Epstein-Barr Virus Reactivation through DNA Demethylation. 2016 Oct 6 3
8 25530093 Identification of a c-Jun homolog from Litopenaeus vannamei as a downstream substrate of JNK in response to WSSV infection. 2015 Apr 2
9 25533502 Butein suppresses ICAM-1 expression through the inhibition of IκBα and c-Jun phosphorylation in TNF-α- and PMA-treated HUVECs. 2015 Feb 3
10 25666088 Apigenin inhibits PMA-induced expression of pro-inflammatory cytokines and AP-1 factors in A549 cells. 2015 May 2
11 25698902 Galangin, a novel dietary flavonoid, attenuates metastatic feature via PKC/ERK signaling pathway in TPA-treated liver cancer HepG2 cells. 2015 1
12 25915860 12-O-Tetradecanoylphorbol-13-Acetate Induces Up-Regulated Transcription of Variant 1 but Not Variant 2 of VIL2 in Esophageal Squamous Cell Carcinoma Cells via ERK1/2/AP-1/Sp1 Signaling. 2015 5
13 26431317 Synergistic Gene Expression Signature Observed in TK6 Cells upon Co-Exposure to UVC-Irradiation and Protein Kinase C-Activating Tumor Promoters. 2015 1
14 23396363 SUMOylation of the inducible (c-Fos:c-Jun)/AP-1 transcription complex occurs on target promoters to limit transcriptional activation. 2014 Feb 13 2
15 24743307 The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure. 2014 Apr 1
16 24753227 Resveratrol stimulates AP-1-regulated gene transcription. 2014 Jul 1
17 24796531 Differentiation-associated genes regulated by c-Jun and decreased in the progression of esophageal squamous cell carcinoma. 2014 1
18 25143809 The Heterochromatin-1 Phosphorylation Contributes to TPA-Induced AP-1 Expression. 2014 Jul 2
19 22351517 The possible separation of 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation and hyperplasia by compound A. 2013 Jun 2
20 23647419 Evolutionary conservation of an atypical glucocorticoid-responsive element in the human tyrosine hydroxylase gene. 2013 Jul 2
21 21377232 Similar cellular proliferation activities in nasal polyps and adjacent inferior turbinate. 2012 Jan-Feb 2
22 22151918 Cucurbitacin B inhibits 12-O-tetradecanoylphorbol 13-acetate-induced invasion and migration of human hepatoma cells through inactivating mitogen-activated protein kinase and PI3K/Akt signal transduction pathways. 2012 Apr 1
23 22299029 Differential role of PKC-induced c-Jun in HTLV-1 LTR activation by 12-O-tetradecanoylphorbol-13-acetate in different human T-cell lines. 2012 1
24 22505246 Phosphoinositol 3-kinase, a novel target molecule for the inhibitory effects of juglone on TPA-induced cell transformation. 2012 Jul 1
25 22561169 Manganese promotes phorbol ester-induced interleukin-2 production via AP-1 activation in Jurkat T-cells. 2012 Jun 20 4
26 21106746 The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF-{kappa}B sites during acute infection. 2011 Feb 2
27 21864583 Zac1 functional interactions mediate AP-1 transcriptional activity. 2011 Dec 4
28 19768635 Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells. 2010 Feb 2
29 19853631 Transcription factor AP1 modulates the internal promoter activity of bovine foamy virus. 2010 Jan 1
30 20025870 Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways. 2010 Feb 15 1
31 20053986 Heterodimerization with different Jun proteins controls c-Fos intranuclear dynamics and distribution. 2010 Feb 26 2
32 20131957 Hyul-Tong-Ryung suppresses PMA-induced MMP-9 expression by inhibiting AP-1-mediated gene expression via ERK 1/2 signaling pathway in MCF-7 human breast cancer cells. 2010 Dec 3
33 20152819 Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms. 2010 Jun 15 3
34 20492173 alpha-Mangostin, a novel dietary xanthone, suppresses TPA-mediated MMP-2 and MMP-9 expressions through the ERK signaling pathway in MCF-7 human breast adenocarcinoma cells. 2010 Jan-Feb 1
35 20492175 Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-kappaB and AP-1. 2010 Jan-Feb 3
36 20590612 Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Calpha-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated kinase/activator protein-1. 2010 Jul 6
37 19130490 Molecular mechanisms of nitric oxide-dependent inhibition of TPA-induced matrix metalloproteinase-9 (MMP-9) in MCF-7 cells. 2009 May 1
38 19164581 The coactivator CRTC1 promotes cell proliferation and transformation via AP-1. 2009 Feb 3 6
39 19176525 Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated Activation of Transcription. 2009 Mar 27 2
40 19418353 Inhibitory effect of immature plum on PMA-induced MMP-9 expression in human hepatocellular carcinoma. 2009 1
41 19541923 p53 inhibition of AP1-dependent TFF2 expression induces apoptosis and inhibits cell migration in gastric cancer cells. 2009 Aug 1
42 18024477 Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1. 2008 Jan 4
43 18541274 Attenuation of interferon-gamma mRNA expression in activated Jurkat T cells by exogenous zinc via down-regulation of the calcium-independent PKC-AP-1 signaling pathway. 2008 Jul 4 4
44 18628248 Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells. 2008 Sep 5
45 19018257 Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells. 2008 Dec 16 1
46 16888805 Interleukin-1beta and tetradecanoylphorbol acetate-induced biosynthesis of tumor necrosis factor alpha in human hepatoma cells involves the transcription factors ATF2 and c-Jun and stress-activated protein kinases. 2007 Jan 1 3
47 17215518 PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells. 2007 Mar 6
48 17314023 Retrodifferentiation and rejuvenation of senescent monocytic cells requires PARP-1. 2007 Jun 1
49 17404068 KG-135 inhibits COX-2 expression by blocking the activation of JNK and AP-1 in phorbol ester-stimulated human breast epithelial cells. 2007 Jan 4
50 16478997 Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription. 2006 Mar 2