Losartan

angiotensin II receptor, type 1a ; Mus musculus







75 Article(s)
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1 34969261 Angiotensin II-Induced Erythrocyte Senescence Contributes to Oxidative Stress. 2022 Feb 1
2 31574424 Losartan modulates brain inflammation and improves mood disorders and memory impairment induced by innate immune activation: The role of PPAR-γ activation. 2020 Jan 1
3 32475319 Evidence for a Physiological Mitochondrial Angiotensin II System in the Kidney Proximal Tubules: Novel Roles of Mitochondrial Ang II/AT1a/O2- and Ang II/AT2/NO Signaling. 2020 Jul 1
4 31132127 Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model. 2019 Aug 1 1
5 29570626 Angiotensin II-Induced Mesangial Cell Damaged Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non-Selective Channels. 2018 Mar 23 1
6 30687708 Sensitization of the Angiotensin II AT1 Receptor Contributes to RKIP-Induced Symptoms of Heart Failure. 2018 2
7 32524006 Local activation of the pulmonary extravascular angiotensin system induces epithelial apoptosis and lung fibrosis. 2018 1
8 28063227 LIPUS suppressed LPS-induced IL-1α through the inhibition of NF-κB nuclear translocation via AT1-PLCβ pathway in MC3T3-E1 cells. 2017 Dec 2
9 28842434 Enhanced hemodynamic responses to angiotensin II in diabetes are associated with increased expression and activity of AT1 receptors in the afferent arteriole. 2017 Oct 1 1
10 26909880 Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice. 2016 Mar 1
11 27045029 Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. 2016 May 1
12 27210827 The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mice. 2016 Aug 2
13 27401876 Involvement of Spinal Angiotensin II System in Streptozotocin-Induced Diabetic Neuropathic Pain in Mice. 2016 Sep 1
14 27670279 Blockade of the renin-angiotensin system prevents acute and immunologically relevant colitis in murine models. 2016 Dec 1
15 27983984 Angiotensin Ⅱ induces the differentiation of mouse epicardial progenitor cells into vascular smooth muscle-like cells. 2016 Nov 25 1
16 25445371 The intrathecal administration of losartan, an AT1 receptor antagonist, produces an antinociceptive effect through the inhibiton of p38 MAPK phosphorylation in the mouse formalin test. 2015 Jan 12 2
17 26209257 Involvement of p38 MAPK activation mediated through AT1 receptors on spinal astrocytes and neurons in angiotensin II- and III-induced nociceptive behavior in mice. 2015 Dec 1
18 26494430 Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis. 2015 Oct 23 2
19 26714035 Effectiveness of Losartan-Loaded Hyaluronic Acid (HA) Micelles for the Reduction of Advanced Hepatic Fibrosis in C3H/HeN Mice Model. 2015 2
20 24101294 Novel role of mechanosensitive AT1B receptors in myogenic vasoconstriction. 2014 Jul 1
21 24355917 Aortic aneurysms in Loeys-Dietz syndrome - a tale of two pathways? 2014 Jan 1
22 24942113 Vasomotor effects of acetylcholine, bradykinin, noradrenaline, 5-hydroxytryptamine, histamine and angiotensin II on the mouse basilar artery. 2014 Oct 1
23 25046440 Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice. 2014 Aug 1
24 25080489 Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase. 2014 Oct 1 1
25 25122005 Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. 2014 1
26 25169953 Participation of AT1 and Mas receptors in the modulation of inflammatory pain. 2014 Nov 1
27 23636094 Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice. 2013 May 1 1
28 23727291 Mechanisms of the anti-inflammatory actions of the angiotensin type 1 receptor antagonist losartan in experimental models of arthritis. 2013 Aug 1
29 23762470 Beneficial effects of the activation of the angiotensin-(1-7) MAS receptor in a murine model of adriamycin-induced nephropathy. 2013 2
30 23796502 Angiotensin II regulates collagen metabolism through modulating tissue inhibitor of metalloproteinase-1 in diabetic skin tissues. 2013 Sep 1
31 24095877 Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK. 2013 Dec 2
32 22497828 Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner. 2012 Apr 17 2
33 22943509 Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A). 2012 Sep 3 2
34 20813770 Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy. 2011 Mar 1
35 21109230 Angiotensin II induces interleukin-6 synthesis in osteoblasts through ERK1/2 pathway via AT1 receptor. 2011 Mar 1
36 21487074 Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage. 2011 Jul 1
37 21493863 Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. 2011 Apr 15 1
38 19765632 Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells. 2010 Jan 15 3
39 20667471 Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2). 2010 Dec 2
40 20722567 Ang II enhances tubular cell Ets-1 expression and associated down stream signaling is mediated through AT1 receptors. 2010 1
41 18847324 Activation of renin-angiotensin system induces osteoporosis independently of hypertension. 2009 Feb 1
42 18045833 In vivo regulation of AT1a receptor-mediated intracellular uptake of [125I]Val5-ANG II in the kidneys and adrenals of AT1a receptor-deficient mice. 2008 Feb 1
43 18307747 Cardioprotection and kallikrein-kinin system in acute myocardial ischaemia in mice. 2008 Apr 2
44 17429342 Modulation of angiotensin II and norepinephrine-induced plasminogen activator inhibitor-1 expression by AT1a receptor deficiency. 2007 Jul 1
45 16595708 Angiotensin II stimulates the synthesis of vascular endothelial growth factor through the p38 mitogen activated protein kinase pathway in cultured mouse podocytes. 2006 Apr 1
46 16601194 Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. 2006 Apr 7 2
47 15944203 Enhanced osmotic responsiveness in angiotensin AT1a receptor deficient mice: evidence for a role for AT1b receptors. 2005 Sep 2
48 14662650 Cardiovascular and renal phenotype in mice with one or two renin genes. 2004 Jan 1
49 14722647 Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. 2004 Feb 1
50 15131008 Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. 2004 Jun 25 1