Tyrosine

inositol polyphosphate-5-phosphatase D ; Homo sapiens







71 Article(s)
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1 31308061 Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks. 2019 Sep 15 2
2 29852247 Nuclear accumulation of SHIP1 mutants derived from AML patients leads to increased proliferation of leukemic cells. 2018 Sep 4
3 27206658 Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype. 2016 May 20 2
4 27456487 FcγRIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells. 2016 Sep 1 1
5 27550373 The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner. 2016 Nov 1
6 25312647 Immune cell inhibition by SLAMF7 is mediated by a mechanism requiring src kinases, CD45, and SHIP-1 that is defective in multiple myeloma cells. 2015 Jan 2
7 26304991 PSTPIP2, a Protein Associated with Autoinflammatory Disease, Interacts with Inhibitory Enzymes SHIP1 and Csk. 2015 Oct 1 1
8 24405601 [Decreased FcγRIIb1 translocation to lipid raft signaling domains in activated B lymphocytes from patients with systemic lupus erythematosus]. 2014 Jan 1
9 22182704 The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: impact on SHIP1/Ig-α interaction. 2012 Feb 2
10 22641604 Reversible Ser/Thr SHIP phosphorylation: a new paradigm in phosphoinositide signalling?: Targeting of SHIP1/2 phosphatases may be controlled by phosphorylation on Ser and Thr residues. 2012 Aug 1
11 22820502 Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling. 2012 Nov 3
12 22078222 Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. 2011 Nov 23 1
13 20308635 Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation. 2010 May 1 1
14 19682241 Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions. 2009 Oct 1
15 18253061 Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. 2008 1
16 18322174 Non-T cell activation linker promotes mast cell survival by dampening the recruitment of SHIP1 by linker for activation of T cells. 2008 Mar 15 3
17 18424727 Suppression of normal and malignant kit signaling by a bispecific antibody linking kit with CD300a. 2008 May 1 1
18 16360206 Granulocyte macrophage-colony stimulating factor reduces the affinity of SHP-2 for the ITIM of CLECSF6 in neutrophils: a new mechanism of action for SHP-2. 2006 Apr 1
19 16682172 The Src homology 2-containing inositol 5-phosphatase 1 (SHIP1) is involved in CD32a signaling in human neutrophils. 2006 Nov 2
20 16876851 SHIP1/2 interaction with tyrosine phosphorylated peptides mimicking an immunoreceptor signalling motif. 2006 1
21 17046573 Insulin and insulin-like growth factor-1 promote mast cell survival via activation of the phosphatidylinositol-3-kinase pathway. 2006 Nov 2
22 15486046 Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes. 2005 Feb 6
23 15735664 The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading. 2005 May 12 1
24 16115887 The B cell inhibitory Fc receptor triggers apoptosis by a novel c-Abl family kinase-dependent pathway. 2005 Oct 21 1
25 14993273 Inhibition of the Jun N-terminal protein kinase pathway by SHIP-1, a lipid phosphatase that interacts with the adaptor molecule Dok-3. 2004 Mar 1
26 15169881 Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors. 2004 Jun 1
27 15363123 Mutation analysis of SHIP gene in acute leukemia. 2004 Aug 2
28 15456754 Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap. 2004 Dec 10 2
29 12506011 Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. 2003 May 1 1
30 12882960 The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity. 2003 Oct 3 1
31 12370370 Src homology 2 domain-containing inositol polyphosphate phosphatase regulates NF-kappa B-mediated gene transcription by phagocytic Fc gamma Rs in human myeloid cells. 2002 Oct 15 3
32 12393695 SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells. 2002 Dec 15 1
33 11453982 Co-clustering of Fcgamma and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking protein. 2001 Jul 1
34 11567986 Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein. 2001 Oct 1 1
35 10623804 Effects of Src homology domain 2 (SH2)-containing inositol phosphatase (SHIP), SH2-containing phosphotyrosine phosphatase (SHP)-1, and SHP-2 SH2 decoy proteins on Fc gamma RIIB1-effector interactions and inhibitory functions. 2000 Jan 15 2
36 10660611 The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor. 2000 Feb 11 5
37 10755621 The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells. 2000 Mar 1
38 10779347 Essential role for the C-terminal noncatalytic region of SHIP in FcgammaRIIB1-mediated inhibitory signaling. 2000 May 1
39 10794720 pp60c-src associates with the SH2-containing inositol-5-phosphatase SHIP1 and is involved in its tyrosine phosphorylation downstream of alphaIIbbeta3 integrin in human platelets. 2000 May 15 6
40 10822173 The phosphatidylinositol polyphosphate 5-phosphatase SHIP1 associates with the dok1 phosphoprotein in bcr-Abl transformed cells. 2000 May 2
41 10875931 Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase. 2000 Sep 22 4
42 11035084 Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling. 2000 Oct 15 2
43 9918857 p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells. 1999 Jan 19 1
44 10066815 The SH2 domain-containing inositol 5'-phosphatase (SHIP) recruits the p85 subunit of phosphoinositide 3-kinase during FcgammaRIIb1-mediated inhibition of B cell receptor signaling. 1999 Mar 12 1
45 10080542 Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells. 1999 Mar 1
46 10194437 Erythropoietin induces the tyrosine phosphorylation of GAB1 and its association with SHC, SHP2, SHIP, and phosphatidylinositol 3-kinase. 1999 Apr 15 1
47 10194451 A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells. 1999 Apr 15 2
48 10207047 The src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytes. 1999 Apr 23 1
49 10229804 CDw150 associates with src-homology 2-containing inositol phosphatase and modulates CD95-mediated apoptosis. 1999 May 15 2
50 10350061 Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31. 1999 Apr 30 1