Benzo(a)pyrene

aryl-hydrocarbon receptor ; Mus musculus







81 Article(s)
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51 17433523 Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation. 2007 Jun 3 1
52 17681673 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells Downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2007 Aug 30 2
53 16256281 Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies. 2006 Apr 10 1
54 17049425 Quantitative analysis of benzo[a]pyrene biotransformation and adduct formation in Ahr knockout mice. 2006 Dec 15 13
55 17145695 Modulation of biological regulatory networks during nephrogenesis. 2006 4
56 18958682 Organic Chemicals Adsorbed onto Diesel Exhaust Particles Directly Alter the Differentiation of Fetal Thymocytes Through Arylhydrocarbon Receptor but Not Oxidative Stress Responses. 2006 Jan 1 1
57 15667830 Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity. 2005 Feb 1 3
58 15034205 Different global gene expression profiles in benzo[a]pyrene- and dioxin-treated vascular smooth muscle cells of AHR-knockout and wild-type mice. 2004 4
59 15621696 Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway. 2004 Nov 1
60 12455047 Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo. 2003 Jan 1 7
61 12884409 Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene. 2003 Jul-Aug 3
62 14530333 T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. 2003 Oct 15 1
63 14613719 Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver. 2003 Nov 15 5
64 11096091 Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells. 2001 Feb 16 4
65 11159756 Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo. 2001 Jan 1
66 11577022 Constitutive and inducible expression of Cyp1a1 and Cyp1b1 in vascular smooth muscle cells: role of the Ahr bHLH/PAS transcription factor. 2001 Sep 28 4
67 11733032 Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription. 2001 Nov 6
68 11755119 Protective effects of baicalein and wogonin against benzo[a]pyrene- and aflatoxin B(1)-induced genotoxicities. 2001 Dec 15 1
69 11780955 Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects sperm from DNA damage and apoptosis caused by benzo(a)pyrene. 2001 Sep-Oct 9
70 10639156 Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor. 2000 Jan 18 1
71 10860937 Activation of c-Ha-ras by benzo(a)pyrene in vascular smooth muscle cells involves redox stress and aryl hydrocarbon receptor. 2000 Jul 4
72 9448724 The 4S benzo(a)pyrene-binding protein is not a transcriptional activator of Cyp1a1 gene in Ah receptor-deficient (AHR -/-) transgenic mice. 1998 Jan 15 2
73 10656108 Nonallelism for the audiogenic seizure prone (Asp1) and the aryl hydrocarbon receptor (Ahr) loci in mice. 1998 Nov 1
74 9006915 A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. 1997 Jan 31 3
75 9415707 Identification of benzo[a]pyrene-inducible cis-acting elements within c-Ha-ras transcriptional regulatory sequences. 1997 Dec 2
76 8692887 Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. 1996 Jun 25 2
77 8967965 Basis for the loss of aryl hydrocarbon receptor gene expression in clones of a mouse hepatoma cell line. 1996 Dec 2
78 8148869 Mouse dioxin-inducible cytosolic aldehyde dehydrogenase-3: AHD4 cDNA sequence, genetic mapping, and differences in mRNA levels. 1993 Dec 1
79 6090886 Carcinogen-binding proteins. High-affinity binding sites for benzo[a]pyrene in mouse liver distinct from the Ah receptor. 1984 Sep 1
80 6322977 Binding of benzo(a)pyrene and dibenz(a,h)anthracene to the Ah receptor in mouse and rat hepatic cytosols. 1984 Apr 1
81 288335 Modulation of the in vivo covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity. 1979 1