Phosphatidylcholines

phosphatidylethanolamine N-methyltransferase ; Mus musculus







48 Article(s)
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Pub. Year
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1 33676699 Distribution of perfluorooctane sulfonate in mice and its effect on liver lipidomic. 2021 May 1 4
2 31355949 Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes. 2020 Mar 2
3 31918922 Alternative splicing of UCP1 by non-cell-autonomous action of PEMT. 2020 Jan 2
4 32502648 Implication of phosphatidylethanolamine N-methyltransferase in adipocyte differentiation. 2020 Oct 1 4
5 32582149 Dysregulation of Lipid Metabolism in Macrophages Is Responsible for Severe Endotoxin Tolerance in FcgRIIB-Deficient Lupus Mice. 2020 4
6 30300671 Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice. 2019 Jan 4
7 30615497 A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling. 2019 Apr 4
8 30766963 Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High-Fat Diet. 2019 Feb 3
9 31284753 Hepatic PEMT activity mediates liver health, weight gain, and insulin resistance. 2019 Oct 1 4
10 30281112 Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt-/-/Ldlr-/- Mice. 2018 Oct 1 2
11 28291718 Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria. 2017 Apr 2
12 26603903 Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle. 2016 Feb 4
13 26797396 Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-deficient mice. 2016 Apr 1 4
14 27246581 Metabolomics Reveals Altered Lipid Metabolism in a Mouse Model of Endometriosis. 2016 Aug 5 1
15 25140391 The mouse liver displays daily rhythms in the metabolism of phospholipids and in the activity of lipid synthesizing enzymes. 2015 Feb 2
16 25433161 Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice. 2015 Apr 2
17 26125130 The hepatic circadian clock regulates the choline kinase α gene through the BMAL1-REV-ERBα axis. 2015 1
18 26322888 Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease. 2015 3
19 26391255 Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress. 2015 Dec 4
20 24184426 Phospholipid methylation in mammals: from biochemistry to physiological function. 2014 Jun 4
21 24368431 Choline supplementation protects against liver damage by normalizing cholesterol metabolism in Pemt/Ldlr knockout mice fed a high-fat diet. 2014 Mar 1
22 24667182 Pemt deficiency ameliorates endoplasmic reticulum stress in diabetic nephropathy. 2014 5
23 24677714 The concentration of phosphatidylethanolamine in mitochondria can modulate ATP production and glucose metabolism in mice. 2014 Aug 7
24 24963152 Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice. 2014 Oct 2
25 22877991 Physiological roles of phosphatidylethanolamine N-methyltransferase. 2013 Mar 4
26 23505042 Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. 2013 Oct 4
27 21411618 Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans. 2011 May 2
28 21454708 Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo. 2011 May 13 2
29 20150657 A role for Sp1 in transcriptional regulation of phosphatidylethanolamine N-methyltransferase in liver and 3T3-L1 adipocytes. 2010 Apr 16 2
30 20452975 Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity. 2010 Jul 16 2
31 19520976 Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice. 2009 Sep 3
32 18842588 A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase. 2008 Dec 19 6
33 17283071 Choline redistribution during adaptation to choline deprivation. 2007 Apr 6 2
34 17292664 Choline cannot be replaced by propanolamine in mice. 2007 Apr 2
35 17513168 A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis. 2007 Jul 1
36 17595447 The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion. 2007 Sep 5
37 16679290 The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. 2006 May 3
38 16144842 Phosphatidylcholine homeostasis and liver failure. 2005 Nov 11 4
39 12466019 Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline. 2003 Mar 15 3
40 12482759 Plasma homocysteine is regulated by phospholipid methylation. 2003 Feb 21 1
41 12668679 A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice. 2003 Jun 13 6
42 12837848 Insights into the requirement of phosphatidylcholine synthesis for liver function in mice. 2003 Oct 9
43 14608048 Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. 2003 Nov 8
44 12193594 An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins. 2002 Nov 1 4
45 10462379 The unique acyl chain specificity of biliary phosphatidylcholines in mice is independent of their biosynthetic origin in the liver. 1999 Sep 3
46 9765216 Biochemical and evolutionary significance of phospholipid methylation. 1998 Oct 16 3
47 9371769 Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase. 1997 Nov 25 3
48 2126577 Purification and properties of phosphatidyl-N-monomethylethanolamine N-methyltransferase, the enzyme catalyzing the second and the third steps in the phosphatidylethanolamine N-methyltransferase system, from mouse liver microsomes. 1990 Jun 1