| 1 |
34303734 | Multidrug resistance-associated protein 2 is negatively regulated by oxidative stress in rat intestine via a posttranslational mechanism. Impact on its membrane barrier function. | 2021 Aug |
1 |
| 2 |
32860804 | Spironolactone ameliorates lipopolysaccharide-induced cholestasis in rats by improving Mrp2 function: Role of transcriptional and post-transcriptional mechanisms. | 2020 Oct 15 |
2 |
| 3 |
29032155 | Functional characterisation of glutathione export from the rat lens. | 2018 Jan |
6 |
| 4 |
28298215 | Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood-brain barrier following hypoxia-reoxygenation stress. | 2017 Mar 16 |
3 |
| 5 |
25450747 | Consequences of Mrp2 deficiency for diclofenac toxicity in the rat intestine ex vivo. | 2015 Feb |
1 |
| 6 |
23220748 | Ticlopidine, a cholestatic liver injury-inducible drug, causes dysfunction of bile formation via diminished biliary secretion of phospholipids: involvement of biliary-excreted glutathione-conjugated ticlopidine metabolites. | 2013 Feb |
1 |
| 7 |
23683258 | Carbon monoxide may enhance bile secretion by increasing glutathione excretion and Mrp2 expression in rats. | 2013 May |
1 |
| 8 |
22330094 | Sustained intrahepatic glutathione depletion causes proteasomal degradation of multidrug resistance-associated protein 2 in rat liver. | 2012 Jun |
2 |
| 9 |
22508486 | Effects of glycyrrhizin on biliary transport and hepatic levels of glutathione in rats. | 2012 Jul |
2 |
| 10 |
21839169 | Interaction of Mrp2 with radixin causes reversible canalicular Mrp2 localization induced by intracellular redox status. | 2011 Nov |
2 |
| 11 |
20584751 | Selenium-dependent and -independent transport of arsenic by the human multidrug resistance protein 2 (MRP2/ABCC2): implications for the mutual detoxification of arsenic and selenium. | 2010 Aug |
2 |
| 12 |
20683964 | Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat. | 2010 Aug |
1 |
| 13 |
19339379 | Correlation between apical localization of Abcc2/Mrp2 and phosphorylation status of ezrin in rat intestine. | 2009 Jul |
1 |
| 14 |
19782883 | Influence of luminal monosaccharides on secretion of glutathione conjugates from rat small intestine in vitro. | 2009 Nov 3 |
4 |
| 15 |
19897918 | Compensatory expression of MRP3 in the livers of MRP2-deficient EHBRs is promoted by DHA intake. | 2009 Nov |
1 |
| 16 |
18700187 | Retrieval of the rat canalicular conjugate export pump Mrp2 is associated with a rearrangement of actin filaments and radixin in bile salt-induced cholestasis. | 2008 Jul 28 |
1 |
| 17 |
18787061 | Canalicular Mrp2 localization is reversibly regulated by the intracellular redox status. | 2008 Nov |
3 |
| 18 |
16737587 | [Effects of MRP2-GSH cotransport system on hepatic arsenic metabolism in rats]. | 2006 May |
2 |
| 19 |
15652244 | Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2. | 2005 Feb 1 |
1 |
| 20 |
15863252 | Dapsone impairs the bile salt-independent fraction of bile flow in rats: Possible involvement of its N-hydroxylated metabolite. | 2005 Jul 1 |
4 |
| 21 |
16271353 | Transport deficient (TR-) hyperbilirubinemic rats are resistant to acetaminophen hepatotoxicity. | 2005 Dec 5 |
1 |
| 22 |
15276087 | Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein. | 2004 Aug 15 |
3 |
| 23 |
15528031 | Ethacrynic-acid-induced glutathione depletion and oxidative stress in normal and Mrp2-deficient rat liver. | 2004 Dec 1 |
1 |
| 24 |
12756215 | Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats. | 2003 Jun |
3 |
| 25 |
12893631 | Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells. | 2003 Dec |
13 |
| 26 |
11853683 | Inhibition of Mrp2- and Ycf1p-mediated transport by reducing agents: evidence for GSH transport on rat Mrp2. | 2002 Feb 15 |
4 |
| 27 |
11174078 | No effect of phenobarbital pretreatment of rats on methotrexate pharmacokinetics in the isolated liver perfused in a single-pass way. | 2001 Feb |
1 |
| 28 |
11249855 | Two apical multidrug transporters, P-gp and MRP2, are differently altered in chronic renal failure. | 2001 Apr |
5 |
| 29 |
11306678 | Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats. | 2001 May |
1 |
| 30 |
11306690 | Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2. | 2001 May |
3 |
| 31 |
11323401 | Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo. | 2001 May |
3 |
| 32 |
11557131 | Role of MRP2 and GSH in intrahepatic cycling of toxins. | 2001 Oct 5 |
2 |
| 33 |
10644759 | ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3). | 2000 Jan 28 |
1 |
| 34 |
10869369 | Expression and localization of multidrug resistant protein mrp2 in rat small intestine. | 2000 Jun |
2 |
| 35 |
10937881 | Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene. | 2000 May-Jun |
1 |
| 36 |
10997931 | Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan. | 2000 Oct |
2 |
| 37 |
19003398 | Basolateral and canalicular transport of xenobiotics in the hepatocyte: A review. | 2000 Nov |
2 |
| 38 |
10024515 | Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. | 1999 Mar 1 |
2 |
| 39 |
10194418 | Glutathione S-conjugate transport in hepatocytes entering the cell cycle is preserved by a switch in expression from the apical MRP2 to the basolateral MRP1 transporting protein. | 1999 May |
3 |
| 40 |
10329726 | Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3). | 1999 May 21 |
2 |
| 41 |
10590710 | [Analysis of xenobiotic detoxification system mediated by efflux transporters]. | 1999 Nov |
2 |
| 42 |
10595747 | In vivo cisplatin resistance depending upon canalicular multispecific organic anion transporter (cMOAT). | 1999 Oct |
1 |
| 43 |
9425227 | Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome. | 1998 Feb |
1 |
| 44 |
9495864 | Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats. | 1998 Mar |
1 |
| 45 |
9585089 | Decreased hepatobiliary secretion of inorganic mercury, its deposition and toxicity in the Eisai hyperbilirubinemic rat with no hepatic canalicular organic anion transporter. | 1998 Feb 20 |
1 |
| 46 |
9612274 | Novel properties of hepatic canalicular reduced glutathione transport revealed by radiation inactivation. | 1998 May |
6 |
| 47 |
9875554 | Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2. | 1998 |
5 |
| 48 |
9109389 | Functional expression of the rat liver canalicular isoform of the multidrug resistance-associated protein. | 1997 Apr 7 |
1 |
| 49 |
9328323 | Induction of cMrp/cMoat gene expression by cisplatin, 2-acetylaminofluorene, or cycloheximide in rat hepatocytes. | 1997 Oct |
4 |
| 50 |
9397986 | Modulation of liver canalicular transport processes by the tyrosine-kinase inhibitor genistein: implications of genistein metabolism in the rat. | 1997 Dec |
2 |