Hyaluronic Acid

toll-like receptor 4 ; Mus musculus







44 Article(s)
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1 33486695 Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient L-amino acid-defined diet-induced murine model. 2021 Feb 2
2 32538139 Hyaluronic acid promotes Lgr5+ stem cell proliferation and crypt fission through TLR4 and PGE2 transactivation of EGFR. 2020 Jul 1 6
3 33552081 Nonmicrobial Activation of TLRs Controls Intestinal Growth, Wound Repair, and Radioprotection. 2020 5
4 31484704 Hyaluronic Acid Binding to TLR4 Promotes Proliferation and Blocks Apoptosis in Colon Cancer. 2019 Dec 1
5 27301359 Suppression of Ischemia-Induced Hippocampal Pyramidal Neuron Death by Hyaluronan Tetrasaccharide through Inhibition of Toll-Like Receptor 2 Signaling Pathway. 2016 Aug 1
6 25318610 Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. 2015 Jan 4
7 25537799 Treatment with the hyaluronic Acid synthesis inhibitor 4-methylumbelliferone suppresses LPS-induced lung inflammation. 2015 3
8 25673209 Beta-arrestin 1 is involved in the catabolic response stimulated by hyaluronan degradation in mouse chondrocytes. 2015 Aug 4
9 26321117 Hyaluronan ameliorates LPS-induced acute lung injury in mice via Toll-like receptor (TLR) 4-dependent signaling pathways. 2015 Oct 3
10 26362177 Hyaluronan-induced VEGF-C promotes fibrosis-induced lymphangiogenesis via Toll-like receptor 4-dependent signal pathway. 2015 Oct 23 1
11 26371821 Expression of Concern: TLR4 Is Necessary for Hyaluronan-mediated Airway Hyperresponsiveness after Ozone Inhalation; c-Kit Is Essential for Alveolar Maintenance and Protection from Emphysema-like Disease in Mice. 2015 Sep 15 1
12 26505972 CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice. 2015 Dec 1 5
13 24252748 TLR4, rather than TLR2, regulates wound healing through TGF-β and CCL5 expression. 2014 Feb 2
14 23298137 4-mer hyaluronan oligosaccharides stimulate inflammation response in synovial fibroblasts in part via TAK-1 and in part via p38-MAPK. 2013 4
15 23721397 Hyaluronan fragments induce IFNβ via a novel TLR4-TRIF-TBK1-IRF3-dependent pathway. 2013 May 30 1
16 24058413 Hyaluronic acid oligosaccharides suppress TLR3-dependent cytokine expression in a TLR4-dependent manner. 2013 2
17 21957979 Superoxide dismutase 3 suppresses hyaluronic acid fragments mediated skin inflammation by inhibition of toll-like receptor 4 signaling pathway: superoxide dismutase 3 inhibits reactive oxygen species-induced trafficking of toll-like receptor 4 to lipid rafts. 2012 Feb 15 2
18 22038822 Hyaluronic acid is radioprotective in the intestine through a TLR4 and COX-2-mediated mechanism. 2012 Feb 1 1
19 22197458 Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis. 2012 Feb 1 4
20 22234777 The inhibition of hyaluronan degradation reduced pro-inflammatory cytokines in mouse synovial fibroblasts subjected to collagen-induced arthritis. 2012 Jun 4
21 22287316 Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes. 2012 Jan-Feb 1
22 22796382 The stimulation of adenosine 2A receptor reduces inflammatory response in mouse articular chondrocytes treated with hyaluronan oligosaccharides. 2012 Jul 2
23 21098223 TLR4 through IFN-β promotes low molecular mass hyaluronan-induced neutrophil apoptosis. 2011 Jan 1 2
24 21723389 Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression. 2011 Sep 1
25 21887846 Hyaluronic acid as a rescue therapy for trinitrobenzene sulfonic acid-induced colitis through Cox-2 and PGE2 in a Toll-like receptor 4-dependent way. 2011 Sep 3
26 22073274 Hyaluronan signaling during ozone-induced lung injury requires TLR4, MyD88, and TIRAP. 2011 1
27 19879319 Molecular size hyaluronan differently modulates toll-like receptor-4 in LPS-induced inflammation in mouse chondrocytes. 2010 Feb 1
28 20007931 TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. 2010 Apr 1 2
29 20506365 Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal protein 1 in mice. 2010 Jul 2
30 21037098 Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide. 2010 Dec 1 1
31 18854367 Hyaluronan receptors involved in cytokine induction in monocytes. 2009 Jan 3
32 19277526 Hyaluronic acid fragments evoke Kupffer cells via TLR4 signaling pathway. 2009 Feb 1
33 19574428 CD19, a response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling. 2009 Aug 5
34 19732774 Regulation of colonic epithelial repair in mice by Toll-like receptors and hyaluronic acid. 2009 Dec 1
35 19781786 Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS. 2009 Dec 5
36 19800307 Glycosaminoglycans reduced inflammatory response by modulating toll-like receptor-4 in LPS-stimulated chondrocytes. 2009 Nov 3
37 18434414 Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization. 2008 Jun 3
38 18467694 CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. 2008 Jun 2
39 18641349 Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4. 2008 Aug 1 1
40 18768846 Cathelicidin antimicrobial peptides inhibit hyaluronan-induced cytokine release and modulate chronic allergic dermatitis. 2008 Sep 15 2
41 17164294 Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4. 2007 Jan 1 1
42 17400552 Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2. 2007 Jun 22 7
43 16244651 Regulation of lung injury and repair by Toll-like receptors and hyaluronan. 2005 Nov 1
44 14764599 Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. 2004 Apr 23 3