| 51 |
22422925 | Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner. | 2012 Jun |
1 |
| 52 |
23284726 | Molecular and cellular response profiles induced by the TLR4 agonist-based adjuvant Glucopyranosyl Lipid A. | 2012 |
1 |
| 53 |
21042837 | Incorporation of the TLR4 agonist monophosphoryl lipid A into the bilayer of DDA/TDB liposomes: physico-chemical characterization and induction of CD8+ T-cell responses in vivo. | 2011 Mar |
2 |
| 54 |
21345488 | Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery. | 2011 May |
1 |
| 55 |
21646453 | The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. | 2011 Sep |
1 |
| 56 |
21865549 | Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions. | 2011 Oct 1 |
3 |
| 57 |
20018893 | MD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation. | 2010 Mar 19 |
2 |
| 58 |
20176798 | Substitution of the Bordetella pertussis lipid A phosphate groups with glucosamine is required for robust NF-kappaB activation and release of proinflammatory cytokines in cells expressing human but not murine Toll-like receptor 4-MD-2-CD14. | 2010 May |
2 |
| 59 |
20439476 | The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease. | 2010 Jul |
1 |
| 60 |
21152039 | ATF3 plays a key role in Kdo2-lipid A-induced TLR4-dependent gene expression via NF-κB activation. | 2010 Dec 2 |
2 |
| 61 |
19597529 | All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A. | 2009 Nov-Dec |
2 |
| 62 |
18755299 | An anti-sepsis monomer, 2',5,6',7-tetrahydroxyflavanonol (THF), identified from Scutellaria baicalensis Georgi neutralizes lipopolysaccharide in vitro and in vivo. | 2008 Dec 10 |
1 |
| 63 |
17255219 | Exacerbation of murine ileitis by Toll-like receptor 4 mediated sensing of lipopolysaccharide from commensal Escherichia coli. | 2007 Jul |
1 |
| 64 |
17496062 | Lipid A fraction of LPS induces a discrete MAPK activation in acute lung injury. | 2007 Aug |
3 |
| 65 |
17535644 | Polymyxin B antagonizing biological activity of lipopolysaccharide. | 2007 Jun |
1 |
| 66 |
17581652 | Agonistic and antagonistic properties of a Rhizobium sin-1 lipid A modified by an ether-linked lipid. | 2007 Jul 7 |
1 |
| 67 |
17785847 | Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance. | 2007 Sep 15 |
1 |
| 68 |
17965342 | Chemical structure and immunobiological activity of lipid A from Serratia marcescens LPS. | 2007 Nov |
1 |
| 69 |
16407172 | Structural regions of MD-2 that determine the agonist-antagonist activity of lipid IVa. | 2006 Mar 3 |
1 |
| 70 |
16420741 | Liver argininosuccinate synthase binds to bacterial lipopolysaccharides and lipid A and inactivates their biological activities. | 2006 |
2 |
| 71 |
16549045 | The molecular mechanism of interaction between sushi peptide and Pseudomonas endotoxin. | 2006 Feb |
1 |
| 72 |
16611234 | Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: differential activities of tetra- and penta-acylated lipid A structures on E-selectin expression and TLR4 recognition. | 2006 May |
4 |
| 73 |
17114488 | Recombinant soluble forms of extracellular TLR4 domain and MD-2 inhibit lipopolysaccharide binding on cell surface and dampen lipopolysaccharide-induced pulmonary inflammation in mice. | 2006 Dec 1 |
1 |
| 74 |
15784558 | Lipopolysaccharide preparation extracted from Porphyromonas gingivalis lipoprotein-deficient mutant shows a marked decrease in toll-like receptor 2-mediated signaling. | 2005 Apr |
1 |
| 75 |
15879143 | A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease. | 2005 May 15 |
1 |
| 76 |
16237097 | Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells. | 2005 Nov 1 |
4 |
| 77 |
15100369 | Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4. | 2004 May |
2 |
| 78 |
15184344 | Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization. | 2004 Jul |
2 |
| 79 |
15321997 | Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. | 2004 Sep |
1 |
| 80 |
15373971 | Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling. | 2004 |
1 |
| 81 |
15485838 | Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. | 2004 Dec 24 |
1 |
| 82 |
12717385 | Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. | 2003 May |
1 |
| 83 |
12941142 | Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4. | 2003 Sep |
1 |
| 84 |
12065494 | MD-2, a novel accessory molecule, is involved in species-specific actions of Salmonella lipid A. | 2002 Jul |
2 |
| 85 |
12165529 | Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells. | 2002 Aug 15 |
1 |
| 86 |
12407023 | Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway. | 2002 Nov |
1 |
| 87 |
12462566 | Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide. | 2002 Dec |
1 |
| 88 |
11145687 | Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice. | 2001 Jan 15 |
1 |
| 89 |
11207318 | Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. | 2001 Mar 1 |
2 |
| 90 |
11717200 | Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition. | 2001 Dec |
2 |
| 91 |
10681462 | Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation. | 2000 Feb 29 |
1 |
| 92 |
10742285 | The role of lipopolysaccharide injected systemically in the reactivation of collagen-induced arthritis in mice. | 2000 Apr |
1 |
| 93 |
11024352 | Role of porin of Shigella dysenteriae type 1 in modulation of lipopolysaccharide mediated nitric oxide and interleukin-1 release by murine peritoneal macrophages. | 2000 Oct |
2 |
| 94 |
11067935 | Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. | 2000 Nov 15 |
3 |
| 95 |
9864216 | Interaction of NK lysin, a peptide produced by cytolytic lymphocytes, with endotoxin. | 1999 Jan |
1 |
| 96 |
10064056 | Lipid A directly inhibits IL-4 production by murine Th2 cells but does not inhibit IFN-gamma production by Th1 cells. | 1999 Feb |
1 |
| 97 |
10569739 | Activity of monosaccharide lipid A analogues in human monocytic cells as agonists or antagonists of bacterial lipopolysaccharide. | 1999 Dec |
4 |
| 98 |
9821819 | Structure-activity relationships of lipopolysaccharide (LPS) in tumor necrosis factor-alpha (TNF-alpha) production and induction of macrophage cell death in the presence of cycloheximide (CHX) in a murine macrophage-like cell line, J774.1. | 1998 Oct |
4 |
| 99 |
8613354 | Adenovirus-mediated transfer of a gene encoding acyloxyacyl hydrolase (AOAH) into mice increases tissue and plasma AOAH activity. | 1996 May |
1 |
| 100 |
8933165 | A lipid A analog inhibits LPS-induced cytokine expression and improves survival in endotoxemic mice. | 1996 Nov |
4 |