Lipid A

toll-like receptor 4 ; Mus musculus







121 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35439332 Lipid A Mimetics Based on Unnatural Disaccharide Scaffold as Potent TLR4 Agonists for Prospective Immunotherapeutics and Adjuvants. 2022 Jun 21 1
2 33540826 N-palmitoyl-D-glucosamine, a Natural Monosaccharide-Based Glycolipid, Inhibits TLR4 and Prevents LPS-Induced Inflammation and Neuropathic Pain in Mice. 2021 Feb 2 1
3 33808396 A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice. 2021 Mar 30 1
4 33815382 Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics. 2021 2
5 34113349 Rhodobacter azotoformans LPS (RAP99-LPS) Is a TLR4 Agonist That Inhibits Lung Metastasis and Enhances TLR3-Mediated Chemokine Expression. 2021 1
6 34290146 Sulfatides are endogenous ligands for the TLR4-MD-2 complex. 2021 Jul 27 1
7 34323389 Mobile Colistin Resistance Enzyme MCR-3 Facilitates Bacterial Evasion of Host Phagocytosis. 2021 Sep 1
8 31045990 Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep. 2020 Mar 1
9 32135028 Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes. 2020 Apr 1
10 32389496 Dissociation of TRIF bias and adjuvanticity. 2020 Jun 2 2
11 32448982 A TLR4-TRIF-dependent signaling pathway is required for protective natural tumor-reactive IgM production by B1 cells. 2020 Oct 2
12 30506847 Tumor Lysate-Loaded Lipid Hybrid Nanovaccine Collaborated with an Immune Checkpoint Antagonist for Combination Immunotherapy. 2019 Jan 1
13 31241993 Monophosphoryl lipid A induces protection against LPS in medullary thick ascending limb through induction of Tollip and negative regulation of IRAK-1. 2019 Sep 1 1
14 29339744 Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. 2018 Jan 16 1
15 29535976 Hypoacylated LPS from Foodborne Pathogen Campylobacter jejuni Induces Moderate TLR4-Mediated Inflammatory Response in Murine Macrophages. 2018 1
16 29686054 The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. 2018 Jun 1 1
17 29738228 Enhanced Tumor Retention Effect by Click Chemistry for Improved Cancer Immunochemotherapy. 2018 May 30 1
18 29861179 A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model. 2018 Jun 27 1
19 29867967 Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity. 2018 1
20 28214044 Enhancement of antigen-specific CD4+ and CD8+ T cell responses using a self-assembled biologic nanolipoprotein particle vaccine. 2017 Mar 13 1
21 28348558 Microbiota, Immune Subversion, and Chronic Inflammation. 2017 2
22 28483250 Monophosphoryl lipid A enhances nontypeable Haemophilus influenzae-specific mucosal and systemic immune responses by intranasal immunization. 2017 Jun 1
23 28676095 Toll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α-synucleinopathy. 2017 Jul 4 1
24 26778788 Pre-treatment of C57BL6/J mice with the TLR4 agonist monophosphoryl lipid A prevents LPS-induced sickness behaviors and elevations in dorsal hippocampus interleukin-1β, independent of interleukin-4 expression. 2016 Apr 1 1
25 26826249 Molecular Basis of the Functional Differences between Soluble Human Versus Murine MD-2: Role of Val135 in Transfer of Lipopolysaccharide from CD14 to MD-2. 2016 Mar 1 1
26 26831104 TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. 2016 Feb 16 1
27 27079716 Monophosphoryl Lipid-A: A Promising Tool for Alzheimer's Disease Toll. 2016 Apr 12 1
28 27467924 TLR4/IFNγ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models. 2016 May 1
29 27539854 Characterization of a Novel d-Glycero-d-talo-oct-2-ulosonic acid-substituted Lipid A Moiety in the Lipopolysaccharide Produced by the Acetic Acid Bacterium Acetobacter pasteurianus NBRC 3283. 2016 Sep 30 1
30 25037631 The molecular mechanism of species-specific recognition of lipopolysaccharides by the MD-2/TLR4 receptor complex. 2015 Feb 1
31 25625178 Hexa-acylated LPS-lipid A deploys the appropriate level of fibrin to confer protection through MyD88. 2015 Apr 1
32 25837248 Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces. 2015 May 22 4
33 26081583 MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS. 2015 Oct 1
34 26319313 Species and mediator specific TLR4 antagonism in primary human and murine immune cells by βGlcN(1↔1)αGlc based lipid A mimetics. 2015 Oct 2
35 24420921 Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions. 2014 Feb 15 1
36 24465739 Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide. 2014 1
37 24478065 Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. 2014 Feb 1
38 24654965 Lipid A-based affinity biosensor for screening anti-sepsis components from herbs. 2014 May 23 1
39 24659688 TLR4 ligands lipopolysaccharide and monophosphoryl lipid a differentially regulate effector and memory CD8+ T Cell differentiation. 2014 May 1 1
40 24686069 Phosphoethanolamine decoration of Neisseria gonorrhoeae lipid A plays a dual immunostimulatory and protective role during experimental genital tract infection. 2014 Jun 1
41 25389373 Type I interferon signaling contributes to the bias that Toll-like receptor 4 exhibits for signaling mediated by the adaptor protein TRIF. 2014 Nov 11 2
42 23211623 Intratumoral delivery of low doses of anti-CD40 mAb combined with monophosphoryl lipid a induces local and systemic antitumor effects in immunocompetent and T cell-deficient mice. 2013 Jan 1
43 23314895 Toll-like receptor-4 agonist in post-haemorrhage pneumonia: role of dendritic and natural killer cells. 2013 Nov 1
44 23408095 Recognition of lipid A variants by the TLR4-MD-2 receptor complex. 2013 1
45 23457630 TRIF is required for TLR4 mediated adjuvant effects on T cell clonal expansion. 2013 1
46 23620183 Lipid IVa incompletely activates MyD88-independent Toll-like receptor 4 signaling in mouse macrophage cell lines. 2013 Apr 1
47 23887873 Noncanonical inflammasome activation by intracellular LPS independent of TLR4. 2013 Sep 13 1
48 23952219 Conformationally constrained lipid A mimetics for exploration of structural basis of TLR4/MD-2 activation by lipopolysaccharide. 2013 Nov 15 4
49 22247289 Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction. 2012 Jan 24 1
50 22291184 The importance of adjuvant formulation in the development of a tuberculosis vaccine. 2012 Mar 1 1