| 1 |
33831397 | Homoharringtonine synergizes with quizartinib in FLT3-ITD acute myeloid leukemia by targeting FLT3-AKT-c-Myc pathway. | 2021 Jun |
1 |
| 2 |
34288692 | 3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo. | 2021 Aug 12 |
2 |
| 3 |
34362479 | [Effect of FLT3-ITD Length on 32D Cell Proliferation, Apoptosis and Sensitivity to FLT3 Inhibitor]. | 2021 Aug |
2 |
| 4 |
32215183 | Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells. | 2020 Mar 17 |
1 |
| 5 |
32629802 | CXCR4 Inhibition Enhances Efficacy of FLT3 Inhibitors in FLT3-Mutated AML Augmented by Suppressed TGF-b Signaling. | 2020 Jun 30 |
1 |
| 6 |
32999332 | High-fat diet intensifies MLL-AF9-induced acute myeloid leukemia through activation of the FLT3 signaling in mouse primitive hematopoietic cells. | 2020 Sep 30 |
1 |
| 7 |
30553002 | P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice. | 2019 Feb 10 |
2 |
| 8 |
30590794 | Flt3 inhibition alleviates chronic kidney disease by suppressing CD103+ dendritic cell-mediated T cell activation. | 2019 Nov 1 |
3 |
| 9 |
30770553 | 8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia. | 2019 Feb 15 |
1 |
| 10 |
30923103 | Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL. | 2019 Oct |
3 |
| 11 |
29074603 | Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation. | 2018 Jan 1 |
1 |
| 12 |
29187377 | A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells with FLT3 mutations. | 2018 Jan 25 |
1 |
| 13 |
29854425 | Flt3 Regulation in the Mononuclear Phagocyte System Promotes Ocular Neovascularization. | 2018 |
1 |
| 14 |
28794285 | Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib. | 2017 Aug 9 |
2 |
| 15 |
29209657 | Hitting the snooze button: Inducing quiescence with the FLT3 inhibitor quizartinib protects hematopoietic progenitors from chemotherapy. | 2017 |
3 |
| 16 |
29212189 | Quizartinib (AC220) reverses ABCG2-mediated multidrug resistance: In vitro and in vivo studies. | 2017 Nov 7 |
5 |
| 17 |
27387666 | Internal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21Cdkn1a and Pbx1 in Hematopoietic Cells. | 2016 |
5 |
| 18 |
22990016 | Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling. | 2012 Nov 8 |
2 |