Chlorides

solute carrier family 12 member 2 ; Homo sapiens







63 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35159205 The GABA Polarity Shift and Bumetanide Treatment: Making Sense Requires Unbiased and Undogmatic Analysis. 2022 Jan 24 2
2 35448033 NKCC1 Deficiency in Forming Hippocampal Circuits Triggers Neurodevelopmental Disorder: Role of BDNF-TrkB Signalling. 2022 Apr 15 2
3 33513812 Targeting the WNK-SPAK/OSR1 Pathway and Cation-Chloride Cotransporters for the Therapy of Stroke. 2021 Jan 27 1
4 33534145 Phenobarbital, midazolam, bumetanide, and neonatal seizures: The devil is in the details. 2021 Apr 1
5 33628092 Nonionic surfactant attenuates acute lung injury by restoring epithelial integrity and alveolar fluid clearance. 2021 1
6 34058387 Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome. 2021 Oct 6 1
7 34603048 Loop Diuretics Inhibit Ischemia-Induced Intracellular Ca2+ Overload in Neurons via the Inhibition of Voltage-Gated Ca2+ and Na+ Channels. 2021 1
8 34620512 Pharmacological tools to target NKCC1 in brain disorders. 2021 Dec 1
9 34849164 Role of the cation-chloride-cotransporters in the circadian system. 2021 Sep 1
10 30871970 KCC2 membrane diffusion tunes neuronal chloride homeostasis. 2020 Jun 1 1
11 31930378 GABA in, garbage out: AIS-located proteasomes regulate the developmental GABA switch. 2020 Feb 3 1
12 32081947 Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. 2020 Feb 21 1
13 32322187 Chloride - The Underrated Ion in Nociceptors. 2020 2
14 32973172 Aldosterone up-regulates voltage-gated potassium currents and NKCC1 protein membrane fractions. 2020 Sep 24 1
15 33266310 The Therapeutic Potential of Neuronal K-Cl Co-Transporter KCC2 in Huntington's Disease and Its Comorbidities. 2020 Nov 30 2
16 30484362 Biophysical Modeling Suggests Optimal Drug Combinations for Improving the Efficacy of GABA Agonists after Traumatic Brain Injuries. 2019 May 15 1
17 30590202 Cervical spinal contusion alters Na+-K+-2Cl- and K+-Cl- cation-chloride cotransporter expression in phrenic motor neurons. 2019 Mar 2
18 30784026 A Preliminary Study Evaluating the Safety and Efficacy of Bumetanide, an NKCC1 Inhibitor, in Patients with Drug-Resistant Epilepsy. 2019 Mar 2
19 31792382 Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway. 2019 Dec 1
20 32010056 Role of NKCC1 and KCC2 in Epilepsy: From Expression to Function. 2019 2
21 29729285 Chloride transporters and GABA polarity in developmental, neurological and psychiatric conditions. 2018 Jul 1
22 29782876 Chloride cotransporter KCC2 is essential for GABAergic inhibition in the SCN. 2018 Aug 1
23 28057537 The chloride co-transporters, NKCC1 and KCC2, in experimental autoimmune encephalomyelitis (EAE). 2017 Mar 6 2
24 28074534 Depolarizing γ-aminobutyric acid contributes to glutamatergic network rewiring in epilepsy. 2017 Feb 1
25 26506510 Nonsynaptic glycine release is involved in the early KCC2 expression. 2016 Jul 3
26 26757306 Bumetanide to Treat Parkinson Disease: A Report of 4 Cases. 2016 Jan-Feb 1
27 26966887 Treating Schizophrenia With the Diuretic Bumetanide: A Case Report. 2016 Mar-Apr 1
28 27002180 GABAA receptor-mediated neurotransmission: Not so simple after all. 2016 Sep 1 1
29 25495911 Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis. 2015 Feb 1
30 25724711 Hippocampus and epilepsy: Findings from human tissues. 2015 Mar 1
31 24225328 Seizure-induced disinhibition of the HPA axis increases seizure susceptibility. 2014 Jan 1
32 25072038 GABAergic signaling as therapeutic target for autism spectrum disorders. 2014 2
33 23061490 Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy. 2013 Jan 1
34 23139219 Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. 2013 Jan 15 1
35 23964205 Functional role of ambient GABA in refining neuronal circuits early in postnatal development. 2013 1
36 22121194 Regulatory activation is accompanied by movement in the C terminus of the Na-K-Cl cotransporter (NKCC1). 2012 Jan 13 1
37 22723696 NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension. 2012 Jun 20 4
38 23226777 Changes in expression of the chloride homeostasis-regulating genes, KCC2 and NKCC1, in the blood of cirrhotic patients with hepatic encephalopathy. 2012 Dec 1
39 20819979 Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia. 2011 Jan 2
40 20874805 Mechanosensitive signalling in fish gill and other ion transporting epithelia. 2011 Jul 1
41 21042953 The depolarizing action of GABA controls early network activity in the developing hippocampus. 2011 Apr 1
42 21333799 Chapter 1--importance of chloride homeostasis in the operation of rhythmic motor networks. 2011 1
43 21689072 MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene. 2011 Aug 15 1
44 21733846 WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. 2011 Aug 26 1
45 22131900 Is it safe to use a diuretic to treat seizures early in development ? 2011 Nov 1
46 20231443 Molecular components of signal amplification in olfactory sensory cilia. 2010 Mar 30 1
47 20732874 Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1. 2010 Oct 29 5
48 19036864 NKCC1 and AE3 appear to accumulate chloride in embryonic motoneurons. 2009 Feb 3
49 19406757 Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1. 2009 May 1
50 17918265 Bumetanide enhances phenobarbital efficacy in a neonatal seizure model. 2008 Feb 1