| 1 |
35448033 | NKCC1 Deficiency in Forming Hippocampal Circuits Triggers Neurodevelopmental Disorder: Role of BDNF-TrkB Signalling. | 2022 Apr 15 |
2 |
| 2 |
35524446 | Bumetanide for neonatal seizures: No light in the pharmacokinetic/dynamic tunnel. | 2022 May 6 |
1 |
| 3 |
35095429 | Striatal Chloride Dysregulation and Impaired GABAergic Signaling Due to Cation-Chloride Cotransporter Dysfunction in Huntington's Disease. | 2021 |
2 |
| 4 |
30871970 | KCC2 membrane diffusion tunes neuronal chloride homeostasis. | 2020 Jun 1 |
1 |
| 5 |
31930378 | GABA in, garbage out: AIS-located proteasomes regulate the developmental GABA switch. | 2020 Feb 3 |
2 |
| 6 |
32381101 | Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study. | 2020 May 7 |
1 |
| 7 |
33060559 | Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on? | 2020 Oct 15 |
1 |
| 8 |
33291778 | NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data. | 2020 Dec 4 |
1 |
| 9 |
30597612 | Gamma-aminobutyric acidergic transmission underlies interictal epileptogenicity in pediatric focal cortical dysplasia. | 2019 Feb |
1 |
| 10 |
30977423 | The etiological contribution of GABAergic plasticity to the pathogenesis of neuropathic pain. | 2019 Jan-Dec |
1 |
| 11 |
28057537 | The chloride co-transporters, NKCC1 and KCC2, in experimental autoimmune encephalomyelitis (EAE). | 2017 Mar 6 |
2 |
| 12 |
26506510 | Nonsynaptic glycine release is involved in the early KCC2 expression. | 2016 Jul |
1 |
| 13 |
26955005 | Gain-of-function missense variant in SLC12A2, encoding the bumetanide-sensitive NKCC1 cotransporter, identified in human schizophrenia. | 2016 Jun |
2 |
| 14 |
27939580 | MicroRNA-101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks. | 2016 Dec 21 |
2 |
| 15 |
25495911 | Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis. | 2015 Feb |
2 |
| 16 |
25644702 | An evolutionarily conserved switch in response to GABA affects development and behavior of the locomotor circuit of Caenorhabditis elegans. | 2015 Apr |
1 |
| 17 |
26441542 | Development and regulation of chloride homeostasis in the central nervous system. | 2015 |
1 |
| 18 |
24225328 | Seizure-induced disinhibition of the HPA axis increases seizure susceptibility. | 2014 Jan |
1 |
| 19 |
24388924 | Depolarizing chloride gradient in developing cochlear nucleus neurons: underlying mechanism and implication for calcium signaling. | 2014 Mar 7 |
1 |
| 20 |
24695712 | Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia. | 2014 Apr 2 |
2 |
| 21 |
25009229 | Cortical GABAergic excitation contributes to epileptic activities around human glioma. | 2014 Jul 9 |
2 |
| 22 |
25072038 | GABAergic signaling as therapeutic target for autism spectrum disorders. | 2014 |
1 |
| 23 |
23061490 | Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy. | 2013 Jan |
3 |
| 24 |
23406400 | A perturbation of multimodal GABA functions underlying the formation of focal cortical malformations: assessments by using animal models. | 2013 Aug |
2 |
| 25 |
23921125 | DISC1 and SLC12A2 interaction affects human hippocampal function and connectivity. | 2013 Jul |
1 |
| 26 |
23964205 | Functional role of ambient GABA in refining neuronal circuits early in postnatal development. | 2013 |
2 |
| 27 |
22238092 | GABA is excitatory in adult vasopressinergic neuroendocrine cells. | 2012 Jan 11 |
3 |
| 28 |
22447678 | Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. | 2012 Apr |
1 |
| 29 |
22723696 | NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension. | 2012 Jun 20 |
3 |
| 30 |
20624842 | Blocking early GABA depolarization with bumetanide results in permanent alterations in cortical circuits and sensorimotor gating deficits. | 2011 Mar |
3 |
| 31 |
21042953 | The depolarizing action of GABA controls early network activity in the developing hippocampus. | 2011 Apr |
2 |
| 32 |
21635237 | Anomalous levels of Cl- transporters cause a decrease of GABAergic inhibition in human peritumoral epileptic cortex. | 2011 Sep |
3 |
| 33 |
21733846 | WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. | 2011 Aug 26 |
2 |
| 34 |
21795557 | Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. | 2011 Jul 27 |
2 |
| 35 |
20888891 | Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla. | 2010 Dec 29 |
1 |
| 36 |
19004993 | Random stimulation of spider mechanosensory neurons reveals long-lasting excitation by GABA and muscimol. | 2009 Jan |
2 |
| 37 |
19277216 | At immature mossy fibers-CA3 connections, activation of presynaptic GABA(B) receptors by endogenously released GABA contributes to synapses silencing. | 2009 |
2 |
| 38 |
19406757 | Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1. | 2009 May |
2 |
| 39 |
19558450 | GABA action in immature neocortical neurons directly depends on the availability of ketone bodies. | 2009 Aug |
1 |
| 40 |
19821838 | GABAergic signaling induces divergent neuronal Ca2+ responses in the suprachiasmatic nucleus network. | 2009 Oct |
1 |
| 41 |
17918265 | Bumetanide enhances phenobarbital efficacy in a neonatal seizure model. | 2008 Feb |
2 |
| 42 |
18256250 | Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABA(A) signaling in neonatal neurons. | 2008 Feb 6 |
1 |
| 43 |
18448640 | GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1. | 2008 Apr 30 |
2 |
| 44 |
18495878 | Excitatory actions of GABA in the suprachiasmatic nucleus. | 2008 May 21 |
3 |
| 45 |
18495889 | GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation. | 2008 May 21 |
2 |
| 46 |
18497363 | Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses. | 2008 Aug |
1 |
| 47 |
18497364 | Excitatory GABA in rodent developing neocortex in vitro. | 2008 Aug |
2 |
| 48 |
18524541 | Sexually dimorphic expression of KCC2 and GABA function. | 2008 Aug |
1 |
| 49 |
18596173 | Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons. | 2008 Jul 2 |
2 |
| 50 |
18759624 | The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures. | 2008 Sep |
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