Etoposide

protein kinase, DNA-activated, catalytic subunit ; Homo sapiens







21 Article(s)
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1 35097256 Positive Feedback Regulation of Poly(ADP-ribose) Polymerase 1 and the DNA-PK Catalytic Subunit Affects the Sensitivity of Nasopharyngeal Carcinoma to Etoposide. 2022 Jan 25 1
2 35604590 Alternative end-joining originates stable chromosome aberrations induced by etoposide during targeted inhibition of DNA-PKcs in ATM-deficient tumor cells. 2022 May 23 1
3 34208028 Etoposide Triggers Cellular Senescence by Inducing Multiple Centrosomes and Primary Cilia in Adrenocortical Tumor Cells. 2021 Jun 11 4
4 31583565 Inhibition of DNA-PK potentiates the synergistic effect of NK314 and etoposide combination on human glioblastoma cells. 2020 Jan 1
5 29769340 The Human T-Cell Leukemia Virus Type 1 Basic Leucine Zipper Factor Attenuates Repair of Double-Stranded DNA Breaks via Nonhomologous End Joining. 2018 Aug 1 2
6 26152239 Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context. 2015 Dec 1
7 24953561 Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells. 2014 Aug 2
8 23098854 Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation. 2013 Jan 3
9 22282239 PI3K-like kinases restrain Pim gene expression in endothelial cells. 2012 Feb 1
10 22576130 Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K. 2012 Aug 2
11 21245486 NK314 potentiates antitumor activity with adult T-cell leukemia-lymphoma cells by inhibition of dual targets on topoisomerase II{alpha} and DNA-dependent protein kinase. 2011 Mar 31 1
12 21904904 Etoposide-mediated glioblastoma cell death: dependent or independent on the expression of its target, topoisomerase II alpha? 2011 Nov 1
13 19858003 Topoisomerase IIalpha-dependent induction of a persistent DNA damage response in response to transient etoposide exposure. 2010 Feb 1
14 17371003 Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase. 2007 Apr 19 1
15 17441964 DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation. 2007 Jun 1
16 16505093 Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment. 2006 Feb 2
17 15668400 Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs). 2005 Feb 1 1
18 15273254 Relationship between antiapoptotic molecules and metastatic potency and the involvement of DNA-dependent protein kinase in the chemosensitization of metastatic human cancer cells by epidermal growth factor receptor blockade. 2004 Dec 1
19 11864976 The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. 2002 May 10 2
20 11154867 DNA-dependent protein kinase catalytic subunit is cleaved during UV-induced apoptosis. 2001 Jan 2
21 9688310 Resistance to etoposide-induced apoptosis in a Burkitt's lymphoma cell line. 1998 Aug 31 1