Inosine Monophosphate

hypoxanthine phosphoribosyltransferase 1 ; Homo sapiens







24 Article(s)
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1 35114018 Hypoxanthine-guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP. 2022 Apr 2
2 26968365 Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis. 2016 Jun 2
3 21486037 Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate. 2011 May 17 1
4 15990111 The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle. 2005 Aug 5 2
5 16358551 Association between cigarette smoking and hypoxanthine guanine phosphoribosyltransferase activity. 2005 Nov 2
6 12689826 A colorimetric assay for inorganic pyrophosphate that is also useful for measuring product accumulation in polymerase chain reactions. 2003 Apr 15 1
7 11307586 The spectrum of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency. Clinical experience based on 22 patients from 18 Spanish families. 2001 Mar 2
8 10833458 Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes. 2000 Jun 7 4
9 9521733 Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base. 1998 Mar 24 2
10 8976093 [Hypoxanthine guanine phosphoribosyl transferase]. 1996 Dec 2
11 8128888 The effect of high-intensity training on purine metabolism in man. 1993 Dec 2
12 1311306 Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity. 1992 Mar 5 1
13 1583701 Metabolic fate of hypoxanthine and inosine in cultured cardiomyocytes. 1992 Feb 1
14 1703446 Expression of the hypoxanthine phosphoribosyl transferase gene in resting and growth-stimulated human lymphocytes. 1991 Jan 17 1
15 2071157 Determination of the mutations responsible for the Lesch-Nyhan syndrome in 17 subjects. 1991 Jun 2
16 2543233 Modified GMP-affinity chromatography for the purification of mutant hypoxanthine phosphoribosyltransferase. 1989 Apr 2
17 2566318 Guanine ribonucleotide metabolism in human red blood cells: evidence for a high rate of GMP dephosphorylation. 1989 Apr 1
18 2617949 [Physico-chemical and catalytic properties of hypoxanthine guanine phosphoribosyltransferase in thrombocytes from blood donors and patients with hemophilia A]. 1989 Sep-Oct 1
19 2437821 A method for the determination of 5-phosphoribosyl 1-pyrophosphate concentrations in erythrocytes using high-performance liquid chromatography. 1987 Feb 1 1
20 3436062 Screening for adenine and hypoxanthine phosphoribosyltransferase deficiencies in human erythrocytes by high-performance liquid chromatography. 1987 Dec 1
21 3936863 Simultaneous high-performance liquid chromatographic assay of the activities of erythrocytic hypoxanthine-guanine phosphoribosyl transferase and purine nucleoside phosphorylase. 1985 Dec 11 1
22 6717466 Induction of mutations by chemical agents at the hypoxanthine-guanine phosphoribosyl transferase locus in human epithelial teratoma cells. 1984 Apr 4
23 6258915 Characterization of purine nucleotide metabolism in cultured fibroblasts with deficiency of hypoxanthine-guanine phosphoribosyltransferase and with superactivity of phosphoribosylpyrophosphate synthetase. 1980 2
24 5256231 Purine requirement of cells cultured from humans affected with Lesch-Nyhan syndrome (hypoxanthine-guanine phosphoribosyltransferase deficiency). 1969 Feb 1