Purines

hypoxanthine phosphoribosyltransferase 1 ; Homo sapiens







15 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 35194983 Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation. 2022 Mar 18 1
2 31971609 Perfecting a high hypoxanthine phosphoribosyltransferase activity-uricase KO mice to test the effects of purine- and non-purine-type xanthine dehydrogenase (XDH) inhibitors. 2020 May 1
3 30831305 Understanding the structure-function relationship of HPRT1 missense mutations in association with Lesch-Nyhan disease and HPRT1-related gout by in silico mutational analysis. 2019 Apr 4
4 31552824 Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. 2019 Sep 25 1
5 31574190 HPRT and Purine Salvaging Are Critical for Hematopoietic Stem Cell Function. 2019 Dec 1
6 27375492 Plasma Hypoxanthine-Guanine Phosphoribosyl Transferase Activity in Bottlenose Dolphins Contributes to Avoiding Accumulation of Non-recyclable Purines. 2016 3
7 25481104 Clinical severity in Lesch-Nyhan disease: the role of residual enzyme and compensatory pathways. 2015 Jan 1
8 19342420 Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis. 2009 Jul 1 1
9 2572141 Molecular analysis of hypoxanthine-guanine phosphoribosyltransferase mutations in five unrelated Japanese patients. 1989 Jun 2
10 6087154 Molecular evidence for new mutation at the hprt locus in Lesch-Nyhan patients. 1984 Aug 2-8 2
11 523196 Utilization of purines by an HPRT variant in an intelligent, nonmutilative patient with features of the Lesch-Nyhan syndrome. 1979 Dec 1
12 214700 Kinetic aspects of purine metabolism in cultured fibroblasts. A comparative study of cells from patients overproducing purines due to HGPRT deficiency and PRPP synthetase superactivity. 1978 1
13 75575 Purine mutants of mammalian cell lines: III. Control of purine biosynthesis in adenine phosphoribosyl transferase mutants of CHO cells. 1977 Mar 2
14 4693659 Dietary-induced variation of hypoxanthine-guanine phosphoribosyl transferase activity in patients with the Lesch-Nyhan syndrome. 1973 Apr 2
15 4791192 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) deficiency: effect of dietary purines on enzyme activity. 1973 2