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35280287 | Case Report: Thymidine Kinase 2 (TK2) Deficiency: A Novel Mutation Associated With Childhood-Onset Mitochondrial Myopathy and Atypical Progression. | 2022 |
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| 2 |
31060578 | Late-onset thymidine kinase 2 deficiency: a review of 18 cases. | 2019 May 6 |
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| 3 |
29602790 | Retrospective natural history of thymidine kinase 2 deficiency. | 2018 Aug |
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| 4 |
31459030 | Negative Cooperative Binding of Thymidine, Ordered Substrate Binding, and Product Release of Human Mitochondrial Thymidine Kinase 2 Explain Its Complex Kinetic Properties and Physiological Functions. | 2018 Aug 31 |
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| 5 |
26087398 | siRNA knockdown of mitochondrial thymidine kinase 2 (TK2) sensitizes human tumor cells to gemcitabine. | 2015 Sep 8 |
2 |
| 6 |
25215937 | Thymidine kinase 2 enzyme kinetics elucidate the mechanism of thymidine-induced mitochondrial DNA depletion. | 2014 Oct 7 |
4 |
| 7 |
22074768 | Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe. | 2012 Jan 2 |
2 |
| 8 |
22571666 | Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications. | 2012 |
4 |
| 9 |
21444706 | The kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogs. | 2011 Jun |
4 |
| 10 |
21491329 | A mathematical model of human thymidine kinase 2 activity. | 2011 Mar |
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| 11 |
20083405 | Two novel mutations in thymidine kinase-2 cause early onset fatal encephalomyopathy and severe mtDNA depletion. | 2010 Mar |
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| 12 |
18600552 | 5-Bromovinyl 2'-deoxyuridine phosphorylation by mitochondrial and cytosolic thymidine kinase (TK2 and TK1) and its use in selective measurement of TK2 activity in crude extracts. | 2008 Jun |
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| 13 |
17266931 | Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2. | 2007 Mar 16 |
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| 14 |
14690426 | Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms. | 2003 Dec 30 |
1 |
| 15 |
11687801 | Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy. | 2001 Nov |
1 |
| 16 |
10606535 | Stereoisomeric selectivity of human deoxyribonucleoside kinases. | 1999 Dec 21 |
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| 17 |
9461577 | Four deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinase. | 1998 Feb 13 |
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| 18 |
9079672 | Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2. | 1997 Mar 28 |
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| 19 |
9359870 | Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues. | 1997 Nov 15 |
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| 20 |
7637389 | Increased ratio between deoxycytidine kinase and thymidine kinase 2 in CLL lymphocytes compared to normal lymphocytes. | 1995 Jul |
2 |
| 21 |
1359886 | Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues. | 1992 Oct 30 |
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| 22 |
2026611 | Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. | 1991 May 15 |
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