| 1 |
33568930 | Overview on the Discovery and Development of Anti-Inflammatory Drugs: Should the Focus Be on Synthesis or Degradation of PGE2? | 2021 |
1 |
| 2 |
34487716 | Untangling the web of 5-lipoxygenase-derived products from a molecular and structural perspective: The battle between pro- and anti-inflammatory lipid mediators. | 2021 Nov |
1 |
| 3 |
31316498 | Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation. | 2019 |
1 |
| 4 |
28791741 | Molecular dynamics study on the Apo- and Holo-forms of 5-lipoxygenase. | 2018 Jan |
1 |
| 5 |
29355395 | Common structural and pharmacophoric features of mPGES-1 and LTC4S. | 2018 Feb |
1 |
| 6 |
27033421 | Impact of simultaneous stimulation of 5-lipoxygenase and myeloperoxidase in human neutrophils. | 2016 Apr |
1 |
| 7 |
27161402 | Nasturtium (Indian cress, Tropaeolum majus nanum) dually blocks the COX and LOX pathway in primary human immune cells. | 2016 Jun 1 |
1 |
| 8 |
27363940 | Kinetic investigation of human 5-lipoxygenase with arachidonic acid. | 2016 Aug 1 |
1 |
| 9 |
27597418 | Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins. | 2016 Nov 29 |
1 |
| 10 |
29648709 | INHIBITORS OF LEUKOTRIENES SYNTHESIS: NOVEL AGENTS AND THEIR IMPLEMENTATION. | 2016 Jul |
4 |
| 11 |
24480307 | A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity. | 2014 Mar 1 |
1 |
| 12 |
25246560 | Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. | 2014 Oct 7 |
3 |
| 13 |
23727898 | Involvement of 5-lipoxygenase in Alzheimer's disease: a role for DNA methylation. | 2013 |
1 |
| 14 |
23752617 | 5-lipoxygenase antagonist therapy: a new approach towards targeted cancer chemotherapy. | 2013 Sep |
1 |
| 15 |
21169551 | Natural forms of vitamin E and 13'-carboxychromanol, a long-chain vitamin E metabolite, inhibit leukotriene generation from stimulated neutrophils by blocking calcium influx and suppressing 5-lipoxygenase activity, respectively. | 2011 Jan 15 |
1 |
| 16 |
20181674 | 'Lox on neovascularization': leukotrienes as mediators in endothelial biology. | 2010 Apr 1 |
1 |
| 17 |
20016244 | Primers on molecular pathways - lipoxygenases: their role as an oncogenic pathway in pancreatic cancer. | 2009 |
1 |
| 18 |
18448265 | Endogenous pro-resolving and anti-inflammatory lipid mediators: the new hope of atherosclerotic diseases. | 2008 Aug |
1 |
| 19 |
17305569 | Dual acting anti-inflammatory drugs. | 2007 |
2 |
| 20 |
17484769 | Expression of 5-lipoxygenase (5-LOX) in T lymphocytes. | 2007 Oct |
1 |
| 21 |
11966455 | New trends in dual 5-LOX/COX inhibition. | 2002 May |
1 |
| 22 |
11728379 | Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? | 2001 Dec 1 |
2 |
| 23 |
10877840 | Putative role of neuronal 5-lipoxygenase in an aging brain. | 2000 Jul |
1 |
| 24 |
10381823 | Expression of 5-lipoxygenase and 5-lipoxygenase-activating protein in human fetal membranes throughout pregnancy and at term. | 1999 Jul |
2 |
| 25 |
9630716 | Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein. | 1998 Jun 15 |
1 |
| 26 |
7741044 | Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: implications for biological regulation of 5-lipoxygenase. | 1994 Nov |
3 |
| 27 |
8031320 | Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. | 1994 Jun 15 |
1 |