vatalanib

vascular endothelial growth factor A ; Homo sapiens







28 Article(s)
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1 30382439 A phase I study of the vascular endothelial growth factor inhibitor Vatalanib in combination with Pemetrexed disodium in patients with advanced solid tumors. 2019 Aug 2
2 30402031 Advanced tube formation assay using human endothelial colony forming cells for in vitro evaluation of angiogenesis. 2018 Nov 1
3 28644233 Tyrosine Kinase Inhibitor, Vatalanib, Inhibits Proliferation and Migration of Human Pterygial Fibroblasts. 2017 Sep 2
4 25993161 Biology and clinical management challenges in meningioma. 2015 2
5 24939212 Phase II trial of vatalanib in patients with advanced or metastatic pancreatic adenocarcinoma after first-line gemcitabine therapy (PCRT O4-001). 2014 Aug 2
6 23325408 Contribution of increased VEGF receptors to hypoxic changes in fetal ovine carotid artery contractile proteins. 2013 Apr 1 2
7 23508585 PTK787/ZK222584 combined with interferon alpha and 5-fluorouracil synergistically inhibits VEGF signaling pathway in hepatocellular carcinoma. 2013 Dec 2
8 23700288 A phase II study of the oral VEGF receptor tyrosine kinase inhibitor vatalanib (PTK787/ZK222584) in myelodysplastic syndrome: Cancer and Leukemia Group B study 10105 (Alliance). 2013 Oct 6
9 22910317 Vascular density analysis in colorectal cancer patients treated with vatalanib (PTK787/ZK222584) in the randomised CONFIRM trials. 2012 Sep 25 2
10 19945857 EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma. 2010 Jan 4
11 20404549 Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo. 2010 Jun 1 1
12 20682704 Biological evidence for dual antiangiogenic-antiaromatase activity of the VEGFR inhibitor PTK787/ZK222584 in vivo. 2010 Aug 15 2
13 19435899 The vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 inhibits aromatase. 2009 Jun 1 2
14 19622904 Emerging pharmacologic therapies for wet age-related macular degeneration. 2009 1
15 18484796 Neovascular age-related macular degeneration: potential therapies. 2008 1
16 19668729 Current and emerging therapies for the treatment of age-related macular degeneration. 2008 Jun 1
17 17470687 Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer. 2007 Apr 1
18 17628122 Emerging therapies for the treatment of neovascular age-related macular degeneration and diabetic macular edema. 2007 1
19 17846007 [Anti-angiogenic treatment and colorectal cancer]. 2007 Jul 1
20 16407877 Lessons from phase III clinical trials on anti-VEGF therapy for cancer. 2006 Jan 1
21 16600618 Angiogenesis and cancer: A cross-talk between basic science and clinical trials (the "do ut des" paradigm). 2006 Jul 1
22 16882767 Metabolism and disposition of vatalanib (PTK787/ZK-222584) in cancer patients. 2006 Nov 1
23 15708274 Impact of adjuvant inhibition of vascular endothelial growth factor receptor tyrosine kinases on tumor growth delay and local tumor control after fractionated irradiation in human squamous cell carcinomas in nude mice. 2005 Mar 1 1
24 15333517 A dual-color fluorescence imaging-based system for the dissection of antiangiogenic and chemotherapeutic activity of molecules. 2004 Oct 2
25 15479483 Combining anti-VEGF approaches with oxaliplatin in advanced colorectal cancer. 2004 Oct 3
26 14706172 Current studies with PTK787, an oral inhibitor of vascular endothelial growth factor in colorectal cancer. 2003 Nov 1
27 12483548 ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity. 2002 Dec 2
28 11747347 Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth. 2001 Dec 14 2