regorafenib

vascular endothelial growth factor A ; Homo sapiens







32 Article(s)
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1 35261903 Efficacy and safety of regorafenib and fruquintinib as third-line treatment for colorectal cancer: a narrative review. 2022 Jan 1
2 35437784 Plasma levels of VEGF-A and VCAM-1 as predictors of drug-induced hypertension in patients treated with VEGF pathway inhibitors. 2022 Apr 18 2
3 32052681 Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage. 2021 3
4 33436042 The integration of immune checkpoint inhibitors with VEGF targeted agents in advanced gastric and gastroesophageal adenocarcinoma: a review on the rationale and results of early phase trials. 2021 Jan 12 2
5 33916610 Biomarkers Associated with Regorafenib First-Line Treatment Benefits in Metastatic Colorectal Cancer Patients: REFRAME Molecular Study. 2021 Apr 4 1
6 33922992 Induction of Apoptosis, Inhibition of MCL-1, and VEGF-A Expression Are Associated with the Anti-Cancer Efficacy of Magnolol Combined with Regorafenib in Hepatocellular Carcinoma. 2021 Apr 25 3
7 34584898 Second-Line Treatment Options for Hepatocellular Carcinoma: Current Landscape and Future Direction. 2021 1
8 34596810 Catalpol synergistically potentiates the anti-tumour effects of regorafenib against hepatocellular carcinoma via dual inhibition of PI3K/Akt/mTOR/NF-κB and VEGF/VEGFR2 signaling pathways. 2021 Nov 4
9 34940128 Effect of Regorafenib on P2X7 Receptor Expression and Different Oncogenic Signaling Pathways in a Human Breast Cancer Cell Line: A Potential of New Insight of the Antitumor Effects of Regorafenib. 2021 Dec 9 2
10 31608707 The role of PIGF blockade in the treatment of colorectal cancer: overcoming the pitfalls. 2020 Jan 1
11 31195212 Management of adverse events associated with tyrosine kinase inhibitors: Improving outcomes for patients with hepatocellular carcinoma. 2019 Jul 1
12 31238539 Protein Kinase B and Extracellular Signal-Regulated Kinase Inactivation is Associated with Regorafenib-Induced Inhibition of Osteosarcoma Progression In Vitro and In Vivo. 2019 Jun 24 2
13 31856912 Regorafenib plus FOLFIRI with irinotecan dose escalated according to uridine diphosphate glucuronosyltransferase 1A1genotyping in previous treated metastatic colorectal cancer patients:study protocol for a randomized controlled trial. 2019 Dec 19 1
14 32720931 The Mechanism of Action of Regorafenib in Colorectal Cancer: A Guide for the Community Physician. 2019 Aug 1
15 29888133 Shift in VEGFA isoform balance towards more angiogenic variants is associated with tumor stage and differentiation of human hepatocellular carcinoma. 2018 3
16 30378405 A man in his 50s with neurological symptoms during cancer treatment. 2018 Oct 30 4
17 28422758 First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients. 2017 Apr 20 2
18 28954993 Regorafenib induces adaptive resistance of colorectal cancer cells via inhibition of vascular endothelial growth factor receptor. 2017 1
19 29061771 A Systematic Review and Meta-analysis of Retrospective Series of Regorafenib for Treatment of Metastatic Colorectal Cancer. 2017 Nov 1
20 26832420 [Tyrosine kinase inhibiting the VEGF pathway and elderly people: Tolerance, pre-treatment assessment and side effects management]. 2016 Mar 1
21 27117754 Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients. 2016 Apr 27 3
22 27166185 Serum VEGF-A and CCL5 levels as candidate biomarkers for efficacy and toxicity of regorafenib in patients with metastatic colorectal cancer. 2016 Jun 7 2
23 27364975 Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis. 2016 Jul 1 3
24 26045027 Improving patient outcomes with regorafenib for metastatic colorectal cancer - patient selection, dosing, patient education, prophylaxis, and management of adverse events. 2015 1
25 26327919 Management of regorafenib-related toxicities: a review. 2015 Sep 1
26 26399347 The malignant progression effects of regorafenib in human colon cancer cells. 2015 1
27 26451083 Clinical utility of ramucirumab in advanced gastric cancer. 2015 2
28 24623990 Proactive strategies for regorafenib in metastatic colorectal cancer: implications for optimal patient management. 2014 1
29 24772337 Should we move beyond VEGF inhibition in metastatic colorectal cancer? Lessons from early phase clinical trials. 2014 Apr 1
30 25326159 Targeted therapies in metastatic colorectal cancer: a systematic review and assessment of currently available data. 2014 Nov 1
31 23334510 Regorafenib (BAY 73-4506): stromal and oncogenic multikinase inhibitor with potential activity in renal cell carcinoma. 2013 Apr 4
32 24047557 [Regorafenib approved in Metastatic Colorectal cancer]. 2013 Oct 1