Tretinoin

mitogen-activated protein kinase kinase 7 ; Homo sapiens







28 Article(s)
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1 34355652 Trametinib enhances ATRA-induced differentiation in AML cells. 2021 Dec 1
2 34731634 Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. 2021 Nov 2 1
3 32032659 Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. 2020 Jul 1
4 32361568 ERK is involved in the differentiation and function of dimethyl sulfoxide-induced HL-60 neutrophil-like cells, which mimic inflammatory neutrophils. 2020 Jul 1
5 32882760 All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells. 2020 Sep 1
6 30576481 Inhibition of protein phosphatase PPM1D enhances retinoic acid-induced differentiation in human embryonic carcinoma cell line. 2019 Jun 1 1
7 31218101 Combination of enzastaurin and ATRA exerts dose-dependent dual effects on ATRA-resistant acute promyelocytic leukemia cells. 2019 1
8 29131833 MEK inhibitors enhance therapeutic response towards ATRA in NF1 associated malignant peripheral nerve sheath tumors (MPNST) in-vitro. 2017 1
9 27074819 The HER2 inhibitor TAK165 Sensitizes Human Acute Myeloid Leukemia Cells to Retinoic Acid-Induced Myeloid Differentiation by activating MEK/ERK mediated RARα/STAT1 axis. 2016 Apr 14 1
10 27101150 RAF-1/MEK/ERK pathway regulates ATRA-induced differentiation in acute promyelocytic leukemia cells through C/EBPβ, C/EBPε and PU.1. 2016 Jun 5
11 27665842 Staurosporine enhances ATRA-induced granulocytic differentiation in human leukemia U937 cells via the MEK/ERK signaling pathway. 2016 Nov 2
12 24769642 Combined staurosporine and retinoic acid induces differentiation in retinoic acid resistant acute promyelocytic leukemia cell lines. 2014 Apr 28 1
13 23396089 Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells. 2013 Apr 1 1
14 23404856 MEK inhibition leads to lysosome-mediated Na+/I- symporter protein degradation in human breast cancer cells. 2013 Apr 1
15 23554907 The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells. 2013 1
16 23656719 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. 2013 May 9 1
17 20615082 Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells. 2010 Sep 1
18 20655465 NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome. 2010 Jul 23 2
19 19135033 Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation. 2009 Feb 23 1
20 18006504 A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. 2008 Feb 15 1
21 18064629 All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes. 2008 May 1
22 18082883 Retinoid X receptor alpha is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells. 2008 Jun 2
23 18682553 Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. 2008 Aug 12 4
24 17646388 Regulation of mucin gene expression by CREB via a nonclassical retinoic acid signaling pathway. 2007 Oct 1
25 15474987 Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid. 2005 Feb 1
26 11683493 Retinoic acid causes MEK-dependent RAF phosphorylation through RARalpha plus RXR activation in HL-60 cells. 2001 Aug 6
27 10852350 Retinoic acid increases amount of phosphorylated RAF; ectopic expression of cFMS reveals that retinoic acid-induced differentiation is more strongly dependent on ERK2 signaling than induced GO arrest is. 2000 Apr 4
28 9679985 Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest. 1998 Jul 15 3