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29960001 | Flavonoids interfere with NLRP3 inflammasome activation. | 2018 Sep 15 |
4 |
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27903743 | Uric Acid Crystals Induce Placental Inflammation and Alter Trophoblast Function via an IL-1-Dependent Pathway: Implications for Fetal Growth Restriction. | 2017 Jan 1 |
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28084571 | Xanthine Oxidase Induces Foam Cell Formation through LOX-1 and NLRP3 Activation. | 2017 Feb |
2 |
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28394398 | Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis. | 2017 Mar 1 |
2 |
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28569730 | Inflammasomes and IL-1 biology in the pathogenesis of allograft dysfunction. | 2017 Jun 1 |
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29263464 | [Effect of high glucose-based peritoneal dialysis fluids on NLRP3-IL-1β in human peritoneal mesothelial cells]. | 2017 Dec 18 |
2 |
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25589513 | Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases. | 2016 Mar |
2 |
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25829326 | Hyperuricemia-induced inflammasome and kidney diseases. | 2016 Jun |
2 |
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26639394 | Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism. | 2016 Apr |
5 |
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27689075 | Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation. | 2016 |
1 |
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25594175 | Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. | 2015 Jan 15 |
1 |
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25651569 | Hyperuricemia-induced NLRP3 activation of macrophages contributes to the progression of diabetic nephropathy. | 2015 May 1 |
3 |
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25686106 | The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. | 2015 Mar |
1 |
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25761061 | NLRP3 mediates NF-κB activation and cytokine induction in microbially induced and sterile inflammation. | 2015 |
1 |
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25813103 | Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway. | 2015 May |
8 |
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25879284 | Drivers of age-related inflammation and strategies for healthspan extension. | 2015 May |
1 |
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25897296 | Role of the NLRP3 inflammasome in the transient release of IL-1β induced by monosodium urate crystals in human fibroblast-like synoviocytes. | 2015 |
2 |
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26053021 | Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia. | 2015 |
2 |
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26116704 | IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages. | 2015 Oct |
5 |
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26212544 | A new pharmacological effect of levornidazole: Inhibition of NLRP3 inflammasome activation. | 2015 Sep 15 |
2 |
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26234731 | Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation. | 2015 Aug 26 |
1 |
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26238426 | Peroxisome proliferator-activated receptor γ prevents the production of NOD-like receptor family, pyrin domain containing 3 inflammasome and interleukin 1β in HK-2 renal tubular epithelial cells stimulated by monosodium urate crystals. | 2015 Oct |
1 |
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26282945 | Expression of NLRP3 in subcutaneous adipose tissue is associated with coronary atherosclerosis. | 2015 Oct |
1 |
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26435646 | Urate crystals induce NLRP3 inflammasome-dependent IL-1β secretion and proliferation in isolated primary human T-cells. | 2015 Jan-Mar |
2 |
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26546608 | Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation. | 2015 Dec 15 |
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24422572 | IL-1 blockade in autoinflammatory syndromes. | 2014 |
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24703401 | The concept of the inflammasome and its rheumatologic implications. | 2014 Oct |
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25445147 | Activation of NLRP3 inflammasome by crystalline structures via cell surface contact. | 2014 Dec 2 |
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23253918 | Regulation of interleukin 1α secretion by inflammasomes. | 2013 Apr |
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23344781 | Neutrophils, IL-1β, and gout: is there a link? | 2013 Jul |
1 |
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23430110 | Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and human. | 2013 Apr 18 |
2 |
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23762324 | A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast. | 2013 |
1 |
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23798679 | How metabolism generates signals during innate immunity and inflammation. | 2013 Aug 9 |
1 |
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24127597 | Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection. | 2013 Oct 29 |
1 |
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24376319 | Uric acid induces caspase-1 activation, IL-1β secretion and P2X7 receptor dependent proliferation in primary human lymphocytes. | 2013 Apr |
2 |
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24456929 | NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts. | 2013 Nov 1 |
2 |
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22105559 | Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages. | 2012 Mar |
1 |
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22608202 | Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts. | 2012 May 18 |
2 |
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22726397 | Monosodium urate (MSU) crystals increase gout associated coronary heart disease (CHD) risk through the activation of NLRP3 inflammasome. | 2012 Sep 20 |
2 |
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23226314 | Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury. | 2012 |
2 |
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23295692 | Microparticles and their impact on intestinal immunity. | 2012 |
1 |
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1 |
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21234729 | The role of uric acid as an endogenous danger signal in immunity and inflammation. | 2011 Apr |
1 |
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21245324 | Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. | 2011 Feb 1 |
2 |
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21352397 | Uric acid induces trophoblast IL-1β production via the inflammasome: implications for the pathogenesis of preeclampsia. | 2011 Jun |
3 |
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21428959 | Inflammasome activation: from inflammatory disease to infection. | 2011 Apr |
2 |
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21573893 | Danger signals activating innate immunity in graft-versus-host disease. | 2011 Sep |
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20502971 | Recent developments in immune activation by uric acid crystals. | 2010 Aug |
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18390571 | Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process. | 2009 Feb |
1 |