Reactive Oxygen Species

NLR family pyrin domain containing 3 ; Homo sapiens







205 Article(s)
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151 25684031 Activation of the NLRP3/caspase-1 inflammasome in human dental pulp tissue and human dental pulp fibroblasts. 2015 Aug 1
152 25701684 Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients. 2015 May 9
153 25800347 Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation. 2015 Mar 24 2
154 25834143 Helicobacter pylori induces IL-1β and IL-18 production in human monocytic cell line through activation of NLRP3 inflammasome via ROS signaling pathway. 2015 Jun 1
155 25858687 Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome. 2015 Aug 1
156 25863775 Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts. 2015 Aug 1
157 26075098 The Potential Role of the NLRP3 Inflammasome as a Link between Mitochondrial Complex I Dysfunction and Inflammation in Bipolar Disorder. 2015 4
158 26097125 Coculture with Low-Dose SWCNT Attenuates Bacterial Invasion and Inflammation in Human Enterocyte-like Caco-2 Cells. 2015 Sep 9 1
159 26114647 PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection. 2015 3
160 26416893 Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation. 2015 Nov 6 1
161 26435000 Chlorpyrifos induces NLRP3 inflammasome and pyroptosis/apoptosis via mitochondrial oxidative stress in human keratinocyte HaCaT cells. 2015 Dec 2 1
162 24217221 Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways. 2014 Nov 1
163 24307525 Mesenchymal stem/stromal cells inhibit the NLRP3 inflammasome by decreasing mitochondrial reactive oxygen species. 2014 Jun 2
164 24400125 HCV genomic RNA activates the NLRP3 inflammasome in human myeloid cells. 2014 1
165 24776598 LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis. 2014 Sep 1 1
166 24806599 An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells. 2014 May 7 1
167 24820890 Propionibacterium acnes activates the NLRP3 inflammasome in human sebocytes. 2014 Nov 1
168 24850149 Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases. 2014 Jun 2
169 25091898 NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair? 2014 Nov 1
170 25225402 Hemolysis-induced lethality involves inflammasome activation by heme. 2014 Sep 30 1
171 25281528 Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation. 2014 Dec 2
172 25396345 The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3. 2014 Dec 1
173 23211828 IL-1β triggered by peptidoglycan and lipopolysaccharide through TLR2/4 and ROS-NLRP3 inflammasome-dependent pathways is involved in ocular Behçet's disease. 2013 Jan 14 2
174 23278511 Ragweed pollen extract intensifies lipopolysaccharide-induced priming of NLRP3 inflammasome in human macrophages. 2013 Apr 1
175 23315075 Self double-stranded (ds)DNA induces IL-1β production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies. 2013 Feb 15 1
176 23454144 Role of oxidative stress in chemical allergens induced skin cells activation. 2013 Nov 2
177 23954133 Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. 2013 Aug 22 8
178 23977231 S100A8 and S100A9 induce cytokine expression and regulate the NLRP3 inflammasome via ROS-dependent activation of NF-κB(1.). 2013 3
179 24048902 The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity. 2013 Oct 15 3
180 24089192 Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. 2013 Nov 15 1
181 24127597 Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection. 2013 Oct 29 1
182 24357806 Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease. 2013 Dec 19 3
183 22065079 Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma. 2012 Feb 1 1
184 22411934 Inflammaging: disturbed interplay between autophagy and inflammasomes. 2012 Mar 2
185 22446749 Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases. 2012 Sep 2
186 22623753 Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. 2012 May 22 1
187 22796220 Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation. 2012 Aug 24 2
188 22948162 Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. 2012 Oct 19 2
189 23065753 Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma. 2012 Dec 1
190 20632067 Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β. 2011 Jan 1
191 21124315 A role for mitochondria in NLRP3 inflammasome activation. 2011 Jan 13 3
192 21282379 Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). 2011 Mar 14 2
193 21677136 Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. 2011 Jul 15 8
194 21800904 Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. 2011 Sep 27 2
195 21930705 Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation. 2011 Nov 11 1
196 21940680 Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells. 2011 Nov 1 1
197 21957307 Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by both NLRP3 and multiple Toll-like receptors, which independently activate the inflammasome and NF-κB innate response pathways. 2011 Dec 2
198 20075245 The NLRP3 inflammasome: a sensor for metabolic danger? 2010 Jan 15 1
199 20168318 NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production? 2010 Mar 5
200 20407038 Human NLRP3 inflammasome activation is Nox1-4 independent. 2010 Jul 1 2