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NLR family pyrin domain containing 3 ; Homo sapiens







65 Article(s)
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1 34854954 H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion. 2022 Jan 1
2 35023144 ROS-NLRP3 signaling pathway induces sterile inflammation after thulium laser resection of the prostate. 2022 Mar 4
3 35098371 PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages. 2022 Jan 30 2
4 35132157 The role of caspase-1, caspase-4 and NLRP3 in regulating the host cell response evoked by uropathogenic Escherichia coli. 2022 Feb 7 1
5 35138513 TGF-β activates NLRP3 inflammasome by an autocrine production of TGF-β in LX-2 human hepatic stellate cells. 2022 May 1
6 35154136 Role of ROS-Induced NLRP3 Inflammasome Activation in the Formation of Calcium Oxalate Nephrolithiasis. 2022 1
7 35171697 The role of Cl- and K+ efflux in NLRP3 inflammasome and innate immune response activation. 2022 Apr 1 1
8 35219847 Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway. 2022 Mar 1
9 35278669 ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury. 2022 May 1
10 35286219 Mitophagy induction and aryl hydrocarbon receptor-mediated redox signaling contribute to the suppression of breast cancer cell growth by raloxifene via regulation of inflammasomes activation. 2022 Mar 14 1
11 35346830 MiR-1656 targets GPX4 to trigger pyroptosis in broilers kidney tissues by activating NLRP3 inflammasome under Se deficiency. 2022 Jul 1
12 35629435 Translational Medicine in Uremic Vascular Calcification: Scavenging ROS Attenuates p-Cresyl Sulfate-Activated Caspase-1, NLRP3 Inflammasome and Eicosanoid Inflammation in Human Arterial Smooth Muscle Cells. 2022 May 23 2
13 33213267 MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis. 2021 Oct 1
14 33383234 Reduced intracellular antioxidant capacity in platelets contributes to primary immune thrombocytopenia via ROS-NLRP3-caspase-1 pathway. 2021 Mar 1
15 33720048 NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1-infected patients. 2021 Mar 15 1
16 33729569 Protective mechanisms of Taiwanese green propolis toward high glucose-induced inflammation via NLRP3 inflammasome signaling pathway in human gingival fibroblasts. 2021 Aug 1
17 33845232 Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities. 2021 Jul 5 1
18 33967625 Xi Lei San Attenuates Dextran Sulfate Sodium-Induced Colitis in Rats and TNF-α-Stimulated Colitis in CACO2 Cells: Involvement of the NLRP3 Inflammasome and Autophagy. 2021 1
19 34011928 Alternative polyadenylation trans-factor FIP1 exacerbates UUO/IRI-induced kidney injury and contributes to AKI-CKD transition via ROS-NLRP3 axis. 2021 May 19 1
20 34118452 Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren's syndrome. 2021 Aug 1
21 34173812 Fisetin Prevents Oxidized Low-density Lipoprotein-Induced Macrophage Foam Cell Formation. 2021 Nov 1 1
22 34217685 Luteolin prevents THP-1 macrophage pyroptosis by suppressing ROS production via Nrf2 activation. 2021 Aug 25 1
23 34307357 Novel Insights and Current Evidence for Mechanisms of Atherosclerosis: Mitochondrial Dynamics as a Potential Therapeutic Target. 2021 1
24 34384953 AZD8055 ameliorates experimental autoimmune encephalomyelitis via the mTOR/ROS/NLRP3 pathway. 2021 Oct 8 1
25 34387860 AKT controls NLRP3 inflammasome activation by inducing DDX3X phosphorylation. 2021 Oct 1
26 34987391 Methyl Gallate Improves Hyperuricemia Nephropathy Mice Through Inhibiting NLRP3 Pathway. 2021 1
27 31706245 Toxicity of cooking oil fume derived particulate matter: Vitamin D3 protects tubule formation activation in human umbilical vein endothelial cells. 2020 Jan 30 1
28 32057231 Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation. 2020 Mar 24 1
29 32103437 Titanium Ions Play a Synergistic Role in the Activation of NLRP3 Inflammasome in Jurkat T Cells. 2020 Aug 2
30 32128601 Apelin/APJ system: an emerging therapeutic target for respiratory diseases. 2020 Aug 1
31 32272506 Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS. 2020 Jul 3
32 32328491 Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction. 2020 1
33 32432601 Pelargonidin ameliorates CCl4-induced liver fibrosis by suppressing the ROS-NLRP3-IL-1β axis via activating the Nrf2 pathway. 2020 Jun 24 1
34 32716363 β-Glucan-induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies. 2020 Sep 1 1
35 32791262 MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH. 2020 Nov 1
36 32805340 Acrylamide induces NLRP3 inflammasome activation via oxidative stress- and endoplasmic reticulum stress-mediated MAPK pathway in HepG2 cells. 2020 Nov 1
37 33004801 BAFF-driven NLRP3 inflammasome activation in B cells. 2020 Oct 1 1
38 33318544 Activation of NLRP3 by uropathogenic Escherichia coli is associated with IL-1β release and regulation of antimicrobial properties in human neutrophils. 2020 Dec 14 1
39 30439413 Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells. 2019 Jan 1
40 30611121 Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells. 2019 Feb 3
41 30878009 The effects of cooking oil fumes-derived PM2.5 on blood vessel formation through ROS-mediated NLRP3 inflammasome pathway in human umbilical vein endothelial cells. 2019 Jun 15 3
42 31244838 Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts. 2019 1
43 31360100 Caffeine Inhibits NLRP3 Inflammasome Activation by Suppressing MAPK/NF-κB and A2aR Signaling in LPS-Induced THP-1 Macrophages. 2019 1
44 31412804 Uric acid regulates NLRP3/IL-1β signaling pathway and further induces vascular endothelial cells injury in early CKD through ROS activation and K+ efflux. 2019 Aug 14 3
45 31485193 RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose. 2019 4
46 31485604 Overexpression of miR‑200a‑3p promoted inflammation in sepsis‑induced brain injury through ROS‑induced NLRP3. 2019 Nov 1
47 31521245 Melatonin alleviates cigarette smoke-induced endothelial cell pyroptosis through inhibiting ROS/NLRP3 axis. 2019 Nov 5 4
48 29063476 Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production. 2018 Feb 3
49 29098483 Irisin Alleviates Advanced Glycation End Products-Induced Inflammation and Endothelial Dysfunction via Inhibiting ROS-NLRP3 Inflammasome Signaling. 2018 Feb 2
50 29446486 Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway. 2018 Apr 2