lysophosphatidic acid

lysophosphatidic acid receptor 1 ; Homo sapiens







194 Article(s)
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101 22577133 Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells. 2012 Jun 29 1
102 22659570 LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis. 2012 Sep 2
103 22744859 Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis. 2012 Nov 2
104 22782863 Lysophosphatidic acid induces migration of human lung-resident mesenchymal stem cells through the β-catenin pathway. 2012 Sep 2
105 22820196 Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK(1/2) MAP kinases. 2012 Nov 1
106 22911748 Lysophosphatidic acid enhances vascular endothelial growth factor-C expression in human prostate cancer PC-3 cells. 2012 1
107 21102517 Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression. 2011 Mar 17 4
108 21632882 p2y5/LPA(6) attenuates LPA(1)-mediated VE-cadherin translocation and cell-cell dissociation through G(12/13) protein-Src-Rap1. 2011 Oct 1 3
109 21746769 Non-Edg family LPA receptors: the cutting edge of LPA research. 2011 Sep 1
110 21878565 Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling. 2011 Sep 13 2
111 19906815 Lysophosphatidic acid up-regulates expression of growth-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protein-1 in human first-trimester trophoblasts: possible roles in angiogenesis and immune regulation. 2010 Jan 1
112 20044439 LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway. 2010 Mar 3
113 20141599 Regulation of cerebromicrovascular permeability by lysophosphatidic acid. 2010 Jan 1
114 20197381 Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration. 2010 Mar 1
115 20304626 The Nm23-H1 metastasis suppressor as a translational target. 2010 May 1
116 20427710 Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway. 2010 Aug 2
117 21118970 Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer metastasis. 2010 Dec 1 2
118 18592268 Lysophosphatidic acid signaling through LPA receptor subtype 1 induces colony scattering of gastrointestinal cancer cells. 2009 Jan 1
119 18996473 Lysophosphatidic acid signaling in airway epithelium: role in airway inflammation and remodeling. 2009 Mar 1
120 19129242 LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites. 2009 Mar 1
121 19193014 Lysophosphatidic acid protects mesenchymal stem cells against ischemia-induced apoptosis in vivo. 2009 Sep 2
122 19366702 Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation. 2009 Jun 19 2
123 19423373 Toward the three-dimensional structure and lysophosphatidic acid binding characteristics of the LPA(4)/p2y(9)/GPR23 receptor: a homology modeling study. 2009 Aug 1
124 19524700 Non-Edg family lysophosphatidic acid (LPA) receptors. 2009 Sep 2
125 19563736 Signaling pathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells. 2009 May-Jun 1
126 19609003 Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. 2009 Jul 2
127 19656035 Lysophosphatidic Acid signals through specific lysophosphatidic Acid receptor subtypes to control key regenerative responses of human gingival and periodontal ligament fibroblasts. 2009 Aug 1
128 17915188 Lysophosphatidic acid-stimulated interleukin-6 and -8 synthesis through LPA1 receptors on human osteoblasts. 2008 Mar 2
129 18325907 A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese. 2008 Jun 15 1
130 18408217 Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC. 2008 Jun 13 1
131 18627789 Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA(1/3), COX-2, and NF-kappaB activation- and EGFR transactivation-dependent mechanisms. 2008 Oct 1
132 18754873 Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2. 2008 Aug 4
133 19001604 Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells. 2008 Nov 19 2
134 17531530 Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha. 2007 Jul 4
135 17923111 Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3. 2007 Nov 30 3
136 16224106 Neutrophil sphingosine 1-phosphate and lysophosphatidic acid receptors in pneumonia. 2006 Feb 3
137 16353194 Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer. 2006 Jan 1 2
138 16716145 Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA1) in mammalian cells. 2006 Aug 15 3
139 16769891 The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. 2006 Jun 20 2
140 16809448 Expression and function of lysophosphatidic acid LPA1 receptor in prostate cancer cells. 2006 Oct 4
141 16890224 Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblasts. 2006 Aug 21 3
142 15461590 Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells. 2005 Jan 15 2
143 15618220 Lysophosphatidic acid (LPA) protects primary chronic lymphocytic leukemia cells from apoptosis through LPA receptor activation of the anti-apoptotic protein AKT/PKB. 2005 Mar 11 1
144 15728708 LPA2 receptor mediates mitogenic signals in human colon cancer cells. 2005 Jul 1
145 15755723 Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). 2005 May 13 4
146 15837931 G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway. 2005 Apr 26 2
147 15857137 Structure-activity relationships of fluorinated lysophosphatidic acid analogues. 2005 May 5 3
148 16307479 Lysophosphatidic acid affinity chromatography reveals pyruvate kinase as a specific LPA-binding protein. 2005 Nov 1
149 14660630 Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1. 2004 Feb 20 3
150 14744855 Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. 2004 Apr 23 4