lysophosphatidic acid

lysophosphatidic acid receptor 1 ; Homo sapiens







194 Article(s)
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1 34699844 Molecular mechanisms of cyclic phosphatidic acid-induced lymphangiogenic actions in vitro. 2022 Jan 1
2 34982278 LPA3 is a precise therapeutic target and potential biomarker for ovarian cancer. 2022 Jan 4 2
3 35113924 Lateral access mechanism of LPA receptor probed by molecular dynamics simulation. 2022 2
4 35151977 LPA2 promotes neuronal differentiation and neurite formation in neocortical development. 2022 Apr 2 2
5 35260987 Effects of lysophosphatidic acid (LPA) signaling via LPA receptors on cellular functions associated with ATP reduction in osteosarcoma cells treated with ethidium bromide. 2022 Apr 2
6 35391830 Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing. 2022 Apr 15 1
7 35440138 Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators. 2022 Apr 28 1
8 32438456 Microglial lysophosphatidic acid promotes glioblastoma proliferation and migration via LPA1 receptor. 2021 Feb 1
9 32672083 Different effects of lysophosphatidic acid receptor-2 (LPA2) and LPA5 on the regulation of chemoresistance in colon cancer cells. 2021 Feb 4
10 32974731 Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis. 2021 Feb 5
11 33347862 Roles of endothelial cells in the regulation of cell motility via lysophosphatidic acid receptor-2 (LPA2) and LPA3 in osteosarcoma cells. 2021 Feb 2
12 33367557 Lysophosphatidic acid mediated PI3K/Akt activation contributed to esophageal squamous cell cancer progression. 2021 Apr 30 3
13 33553335 CMTM8 as an LPA1-associated partner mediates lysophosphatidic acid-induced pancreatic cancer metastasis. 2021 Jan 4
14 33689121 The linkage between inflammation and fibrosis in muscular dystrophies: The axis autotaxin-lysophosphatidic acid as a new therapeutic target? 2021 Sep 2
15 33704695 Lysophosphatidic acid (LPA) as a modulator of plasma membrane Ca2+-ATPase from basolateral membranes of kidney proximal tubules. 2021 May 1
16 34126459 Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development. 2021 Oct 15 2
17 34302117 Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis. 2021 Sep 1
18 34639115 Lysophosphatidic Acid Mediates Imiquimod-Induced Psoriasis-like Symptoms by Promoting Keratinocyte Proliferation through LPAR1/ROCK2/PI3K/AKT Signaling Pathway. 2021 Oct 5 1
19 34685560 Role of Aberrantly Activated Lysophosphatidic Acid Receptor 1 Signaling Mediated Inflammation in Renal Aging. 2021 Sep 28 4
20 34832985 Design and Development of Autotaxin Inhibitors. 2021 Nov 22 1
21 34969771 Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD). 2021 Dec 2
22 31790581 A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration. 2020 Mar 12 2
23 31811875 LPA1 receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance. 2020 Mar 1 1
24 31852400 LPA receptor signaling as a therapeutic target for radical treatment of neuropathic pain and fibromyalgia. 2020 Jan 1
25 31866407 LPA receptor1 antagonists as anticancer agents suppress human lung tumours. 2020 Feb 5 5
26 31904382 LPA5-mediated signaling induced by endothelial cells and anticancer drug regulates cellular functions of osteosarcoma cells. 2020 Mar 1 2
27 31906413 Lysophosphatidic Acid Upregulates Recepteur D'origine Nantais Expression and Cell Invasion via Egr-1, AP-1, and NF-κB Signaling in Bladder Carcinoma Cells. 2020 Jan 1 2
28 32006610 Effects of lysophosphatidic acid (LPA) receptor-2 (LPA2) and LPA3 on the regulation of chemoresistance to anticancer drug in lung cancer cells. 2020 May 4
29 32007501 Antidepressants induce profibrotic responses via the lysophosphatidic acid receptor LPA1. 2020 Apr 15 2
30 32065590 Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney. 2020 Mar 2 1
31 32301060 Lysophosphatidic acid receptor-2 (LPA2)-mediated signaling enhances chemoresistance in melanoma cells treated with anticancer drugs. 2020 Jun 2
32 32409422 Lysophosphatidic Acid Receptor Agonism: Discovery of Potent Nonlipid Benzofuran Ethanolamine Structures. 2020 Aug 2
33 32469525 Optical Control of Lysophosphatidic Acid Signaling. 2020 Jun 17 2
34 32883524 Cooperation of G12/13 and Gi proteins via lysophosphatidic acid receptor-2 (LPA2) signaling enhances cancer cell survival to cisplatin. 2020 Nov 12 2
35 30447238 LPA Induces Keratinocyte Differentiation and Promotes Skin Barrier Function through the LPAR1/LPAR5-RHO-ROCK-SRF Axis. 2019 May 1
36 30463988 Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry. 2019 Jan 1
37 30849522 LPA1 receptor activation induces PKCα nuclear translocation in glioblastoma cells. 2019 May 2
38 30998970 Lysophosphatidic acid induces integrin β6 expression in human oral squamous cell carcinomas cells via LPAR1 coupling to Gαi and downstream SMAD3 and ETS-1 activation. 2019 Aug 3
39 31191247 Lysophosphatidic Acid and Glutamatergic Transmission. 2019 1
40 31204173 Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis. 2019 Jul 22 3
41 31362892 Modulation of chemoresistance by lysophosphatidic acid (LPA) signaling through LPA5 in melanoma cells treated with anticancer drugs. 2019 Sep 17 2
42 31557675 Lysophosphatidic acid decreased macrophage foam cell migration correlated with downregulation of fucosyltransferase 8 via HNF1α. 2019 Nov 1
43 31633020 LPA1/3 overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction. 2019 Oct 1
44 31781264 Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via p38/ERK MAPK Pathway Mediated by LPA1. 2019 3
45 29051083 Lysophosphatidic acid propagates post-injury Schwann cell dedifferentiation through LPA1 signaling. 2018 Jan 1 2
46 29182028 Altered expression of lysophosphatidic acid receptors, in association with the synthesis of estrogens and androgens in type 1 endometrial cancer biology. 2018 May 1
47 29309788 Involvement of LPA receptor-5 in the enhancement of cell motile activity by phorbol ester and anticancer drug treatments in melanoma A375 cells. 2018 Jan 29 2
48 29329782 LPA-induced migration of ovarian cancer cells requires activation of ERM proteins via LPA1 and LPA2. 2018 Apr 2
49 29369010 Effects of LPA1 and LPA6 on the regulation of colony formation activity in colon cancer cells treated with anticancer drugs. 2018 Feb 4
50 29407582 NM23 downregulation and lysophosphatidic acid receptor EDG2/lpa1 upregulation during myeloid differentiation of human leukemia cells. 2018 Mar 1