Hyaluronic Acid

TNF alpha induced protein 6 ; Homo sapiens







49 Article(s)
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1 34099638 Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner. 2021 Jun 7 1
2 34188166 Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma. 2021 Jun 29 2
3 34909750 Deletion of TNFAIP6 Gene in Human Keratinocytes Demonstrates a Role for TSG-6 to Retain Hyaluronan Inside Epidermis. 2021 Dec 1
4 31044513 Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG-6 expression in a tumor type-specific manner. 2019 Sep 3
5 31484722 Matrix-degrading protease ADAMTS-5 cleaves inter-α-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients. 2019 Oct 18 3
6 26685054 Nuclear Magnetic Resonance Insight into the Multiple Glycosaminoglycan Binding Modes of the Link Module from Human TSG-6. 2016 Jan 19 1
7 26769483 Niche Regulation of Limbal Epithelial Stem Cells: Relationship between Inflammation and Regeneration. 2016 Apr 2
8 26793973 Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It. 2016 1
9 25325979 Analysis of the heavy-chain modification and TSG-6 activity in pathological hyaluronan matrices. 2015 4
10 25548183 MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs. 2015 Jan 13 1
11 24213015 Modulation of tumor necrosis factor-stimulated gene-6 (TSG-6) expression in human endometrium. 2014 Apr 1
12 25135638 Irreversible heavy chain transfer to chondroitin. 2014 Oct 17 2
13 23166324 Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6. 2013 Jan 4 2
14 24005673 Inter-α-inhibitor impairs TSG-6-induced hyaluronan cross-linking. 2013 Oct 11 1
15 22351758 Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex. 2012 Apr 6 3
16 22528482 Heavy chains of inter alpha inhibitor (IαI) inhibit the human complement system at early stages of the cascade. 2012 Jun 8 2
17 22922154 [TSG-6 protein and its role during maturation of ovarian follicles]. 2012 Aug 6 2
18 21239672 Hyaluronan, TSG-6, and inter-α-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules. 2011 Jan 1
19 21596748 The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers. 2011 Jul 22 4
20 21619930 Implication of the oligomeric state of the N-terminal PTX3 domain in cumulus matrix assembly. 2011 Jun 1
21 20100602 Evolutionary conservation of heavy chain protein transfer between glycosaminoglycans. 2010 Apr 3
22 20463016 The TSG-6/HC2-mediated transfer is a dynamic process shuffling heavy chains between glycosaminoglycans. 2010 Jul 16 2
23 19389798 Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6. 2009 Jul 2
24 18448433 The transfer of heavy chains from bikunin proteins to hyaluronan requires both TSG-6 and HC2. 2008 Jul 4 3
25 18806261 Hyaluronan binding to link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH. 2008 Nov 21 1
26 17307731 Determining the molecular basis for the pH-dependent interaction between the link module of human TSG-6 and hyaluronan. 2007 Apr 27 1
27 17585936 Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography. 2007 Aug 17 1
28 17635118 The molecular basis of inter-alpha-inhibitor heavy chain transfer on to hyaluronan. 2007 Aug 4
29 17804111 Hyaluronan-dependent pericellular matrix. 2007 Nov 10 1
30 26627146 Using Molecular Dynamics Simulations To Provide New Insights into Protein Structure on the Nanosecond Timescale:  Comparison with Experimental Data and Biological Inferences for the Hyaluronan-Binding Link Module of TSG-6. 2007 Jan 1
31 16771708 Tumour necrosis factor alpha-stimulated gene-6 inhibits osteoblastic differentiation of human mesenchymal stem cells induced by osteogenic differentiation medium and BMP-2. 2006 Sep 15 3
32 15718240 Towards a structure for a TSG-6.hyaluronan complex by modeling and NMR spectroscopy: insights into other members of the link module superfamily. 2005 May 6 3
33 15840581 Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan. 2005 Jul 8 1
34 14723873 TSG-6 and calcium ions are essential for the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human synovial fluid. 2004 Feb 3
35 15060082 TSG-6 modulates the interaction between hyaluronan and cell surface CD44. 2004 Jun 11 7
36 15110797 Cytokine-induced gene expression at the crossroads of innate immunity, inflammation and fertility: TSG-6 and PTX3/TSG-14. 2004 Apr-Jun 1
37 12622693 Role of tumour necrosis factor stimulated gene 6 (TSG-6) in the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human follicular fluid. 2003 Jan 3
38 12692188 TSG-6: a multifunctional protein associated with inflammation. 2003 May 15 2
39 12889811 Fusion protein of the hyaluronan binding domain from human TSG-6 with luciferase for assay of hyaluronan. 2003 Jul 2
40 12972412 The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding. 2003 Dec 5 2
41 14515153 Inter-alpha-inhibitor, hyaluronan and inflammation. 2003 3
42 12011075 Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6. 2002 Jul 19 3
43 12401803 The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner. 2002 Dec 27 1
44 11287417 Mapping the hyaluronan-binding site on the link module from human tumor necrosis factor-stimulated gene-6 by site-directed mutagenesis. 2001 Jun 22 2
45 10903951 Localization and characterization of the hyaluronan-binding site on the link module from human TSG-6. 2000 Jul 15 2
46 9654129 TSG-6 interacts with hyaluronan and aggrecan in a pH-dependent manner via a common functional element: implications for its regulation in inflamed cartilage. 1998 May 29 1
47 9237673 Overlapping sites on the Link module of human TSG-6 mediate binding to hyaluronan and chrondroitin-4-sulphate. 1997 Jun 30 3
48 9244409 TSG-6: an IL-1/TNF-inducible protein with anti-inflammatory activity. 1997 Jun 1
49 8797823 Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration. 1996 Sep 6 1