Losartan

transforming growth factor, beta 1 ; Mus musculus







36 Article(s)
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1 34094856 Losartan protects against osteoarthritis by repressing the TGF-β1 signaling pathway via upregulation of PPARγ. 2021 Jul 3
2 30610922 Losartan attenuates progression of osteoarthritis in the synovial temporomandibular and knee joints of a chondrodysplasia mouse model through inhibition of TGF-β1 signaling pathway. 2019 Apr 3
3 31284709 Transforming Growth Factor β Receptor Type I Inhibitor, Galunisertib, Has No Beneficial Effects on Aneurysmal Pathological Changes in Marfan Mice. 2019 Jul 9 1
4 31611175 Overexpression of microRNA-21 mediates Ang II-induced renal fibrosis by activating the TGF-β1/Smad3 pathway via suppressing PPARα. 2019 Sep 1
5 30420805 Losartan Alleviates Renal Fibrosis and Inhibits Endothelial-to-Mesenchymal Transition (EMT) Under High-Fat Diet-Induced Hyperglycemia. 2018 3
6 27389178 Losartan improves cerebrovascular function in a mouse model of Alzheimer's disease with combined overproduction of amyloid-β and transforming growth factor-β1. 2017 Jun 2
7 28323879 miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling. 2017 1
8 28768908 Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice. 2017 Aug 3 1
9 26758229 Suppression for lung metastasis by depletion of collagen I and lysyl oxidase via losartan assisted with paclitaxel-loaded pH-sensitive liposomes in breast cancer. 2016 Oct 1
10 26867195 Therapeutic Effect of Losartan, an Angiotensin II Type 1 Receptor Antagonist, on CCl₄-Induced Skeletal Muscle Injury. 2016 Feb 8 1
11 27501834 The Combined Use of Losartan and Muscle-Derived Stem Cells Significantly Improves the Functional Recovery of Muscle in a Young Mouse Model of Contusion Injuries. 2016 Dec 2
12 25556973 Angiotensin receptor I stimulates osteoprogenitor proliferation through TGFβ-mediated signaling. 2015 Jul 1
13 25766329 Life or death by NFκB, Losartan promotes survival in dy2J/dy2J mouse of MDC1A. 2015 Mar 12 2
14 26194911 Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms. 2015 Sep 2
15 24355923 Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. 2014 Jan 1
16 22698430 Novel approach to reduce postsurgical adhesions to a minimum: administration of losartan plus atorvastatin intraperitoneally. 2013 May 1 2
17 23780535 Use of an antifibrotic agent improves the effect of platelet-rich plasma on muscle healing after injury. 2013 Jun 5 1
18 23868934 Aortic remodeling after transverse aortic constriction in mice is attenuated with AT1 receptor blockade. 2013 Sep 1
19 21535912 Losartan enhances the success of myoblast transplantation. 2012 1
20 22348081 Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation. 2012 3
21 22479508 Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition. 2012 1
22 22522482 Losartan, a therapeutic candidate in congenital muscular dystrophy: studies in the dy(2J) /dy(2J) mouse. 2012 May 5
23 22943509 Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A). 2012 Sep 3 1
24 21134900 Tachycardia of atrial myocytes induces collagen expression in atrial fibroblasts through transforming growth factor β1. 2011 Mar 1 1
25 22783312 Novel pharmacological strategies to prevent aortic complications in Marfan syndrome. 2011 Dec 1
26 20112290 Fibronectin synthesis by high glucose level mediated proliferation of mouse embryonic stem cells: Involvement of ANG II and TGF-beta1. 2010 May 1
27 20933212 TGF-β signaling in aortic aneurysm: another round of controversy. 2010 Sep 1
28 21152098 Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. 2010 Nov 30 1
29 19635970 Circulating transforming growth factor-beta in Marfan syndrome. 2009 Aug 11 4
30 18630721 New insights in the pathogenesis of aortic aneurysms. 2008 1
31 17237794 Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states. 2007 Feb 1
32 16601194 Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. 2006 Apr 7 2
33 15487702 Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase. 2004 Summer 1
34 15496155 Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells. 2004 Nov 1
35 11171784 Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. 2001 Feb 13 1
36 10840457 Angiotensin II type 1 receptor antagonist (losartan) down-regulates transforming growth factor-beta in experimental acute pyelonephritis. 2000 Jul 1