Arachidonic Acid

mitochondrially encoded cytochrome c oxidase I ; Homo sapiens







140 Article(s)
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51 19439810 Prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) synthesis is regulated by conjugated linoleic acids (CLA) in human macrophages. 2009 Mar 1
52 19444759 IL-1beta stimulates the expression of prostaglandin receptor EP4 in human chondrocytes by increasing production of prostaglandin E2. 2009 1
53 19553934 COX-1 and vascular disease. 2009 Aug 1
54 19846775 Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells. 2009 Nov 3 1
55 17945191 Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids. 2008 Jan 15 1
56 18220987 Current status of COX-2 inhibitors. 2008 Jan 1
57 18355129 The pathophysiologic role of cyclo-oxygenases in the eye. 2008 Apr 1
58 18818754 Role of linoleic Acid hydroperoxide preformed by cyclooxygenase-1 or -2 on the regulation of prostaglandin formation from arachidonic Acid by the respective enzyme. 2008 Sep 1
59 18829119 Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses. 2008 Nov 15 1
60 17191216 Novel cyclooxygenase-catalyzed bioactive prostaglandin F2alpha from physiology to new principles in inflammation. 2007 Jul 1
61 17380299 The effect of COX-2 inhibitor, nimesulide, on angiogenetic factors in primary endometrial carcinoma cell culture. 2007 Mar 1
62 17878511 Membrane prostaglandin E synthase-1: a novel therapeutic target. 2007 Sep 1
63 18220787 Computer aided drug design approaches to develop cyclooxygenase based novel anti-inflammatory and anti-cancer drugs. 2007 1
64 16454737 Cyclooxygenases regulation by estradiol on endothelium. 2006 1
65 16519514 Molecular dynamics simulations of arachidonic acid complexes with COX-1 and COX-2: insights into equilibrium behavior. 2006 Mar 14 2
66 16519515 Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity. 2006 Mar 14 1
67 16831307 COX-inhibitors relieve the immunosuppressive effect of tumor cells and improve functions of immune effectors. 2006 Apr-Jun 1
68 16842185 Roles of prostanoids in colon carcinogenesis and their potential targeting for cancer chemoprevention. 2006 1
69 16950767 Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid phosphohydrolase-1-dependent. 2006 Nov 3 1
70 17016062 New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro. 2006 1
71 15361066 Human cyclo-oxygenase-1 and an alternative splice variant: contrasts in expression of mRNA, protein and catalytic activities. 2005 Jan 1 1
72 15695510 Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2. 2005 Apr 8 1
73 15850674 New insights into COX-2 biology and inhibition. 2005 Apr 1
74 15867369 Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. 2005 May 1 1
75 15869467 Oxygenation by COX-2 (cyclo-oxygenase-2) of 3-HETE (3-hydroxyeicosatetraenoic acid), a fungal mimetic of arachidonic acid, produces a cascade of novel bioactive 3-hydroxyeicosanoids. 2005 Sep 15 1
76 15892673 The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. 2005 1
77 15936346 Cyclooxygenase-1 signaling is required for vascular tube formation during development. 2005 Jun 1 1
78 15948687 Cyclooxygenase-2-dependent prostaglandin (PG) E2 downregulates matrix metalloproteinase-3 production via EP2/EP4 subtypes of PGE2 receptors in human periodontal ligament cells stimulated with interleukin-1alpha. 2005 Jun 1
79 16113940 Adverse effects of COX-2 inhibitors. 2005 Aug 18 2
80 16150050 Cyclooxygenase-1 haplotype modulates platelet response to aspirin. 2005 Oct 1
81 16190133 Can COX-2 inhibitor-induced increase in cardiovascular disease risk be modified by essential fatty acids? 2005 Jul 1
82 16273333 Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing. 2005 Sep 1
83 29539150 Cyclooxygenase-2-Dependent Prostaglandin (PG) E2 Downregulates Matrix Metalloproteinase-3 Production via EP2 /EP4 Subtypes of PGE2 Receptors in Human Periodontal Ligament Cells Stimulated With Interleukin-1α. 2005 Jun 1
84 14715958 Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia. 2004 Jan 7 1
85 15049901 Cyclooxygenase-2 expression and relationship to tumour progression in human renal cell carcinoma. 2004 Apr 1
86 15158783 New class of potent antinociceptive and antiplatelet 10H-phenothiazine-1-acylhydrazone derivatives. 2004 Jun 15 1
87 15179621 The role of COX-2 inhibition in breast cancer treatment and prevention. 2004 Apr 1
88 15283037 [Specific cyclo-oxygenase-2 inhibitors in cardiovascular pathology]. 2004 Jun 1
89 15301300 Expression and localization of cyclooxigenases (Cox-1 and Cox-2) in nasal respiratory mucosa. Does Cox-2 play a key role in the immunology of nasal polyps? 2004 1
90 15533902 Lack of effect of celecoxib on prostaglandin E2 concentrations in nipple aspirate fluid from women at increased risk of breast cancer. 2004 Nov 1
91 20704950 Aspirin triggers formation of anti-inflammatory mediators: New mechanism for an old drug. 2004 Dec 1
92 12615701 Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. 2003 Mar 1 1
93 12814375 Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor. 2003 Jun 1
94 12841340 Regulation of cytosolic phospholipase A2, cyclooxygenase-1 and -2 expression by PMA, TNFalpha, LPS and M-CSF in human monocytes and macrophages. 2003 Apr 1
95 12874281 Effects of hypoxia on monocyte inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis. 2003 Oct 3 1
96 12971030 Relationship of arachidonic acid concentration to cyclooxygenase-dependent human platelet aggregation. 2003 Sep 1
97 11677234 Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. A critical role for serine 530 and valine 349. 2002 Jan 4 1
98 11821061 Human monocyte-derived dendritic cells are deficient in prostaglandin E2 production. 2002 Jan 30 1
99 11877441 Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells. 2002 May 10 1
100 11909557 Effects of nonsteroidal anti-inflammatory drug therapy on blood pressure and peripheral edema. 2002 Mar 21 1