Lactones

paraoxonase 1 ; Homo sapiens







34 Article(s)
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Pub. Year
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1 35575917 HDL Structure. 2022 1
2 33306925 A Multi-Omics Analysis of PON1 Lactonase Activity in Relation to Human Health and Disease. 2021 Jan 2
3 33562328 Human Paraoxonase-2 (PON2): Protein Functions and Modulation. 2021 Feb 7 1
4 28441923 Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life. 2019 Jun 1
5 30659791 Unexpectedly higher diazoxon hydrolysis by serum paraoxonase-1 in coronary heart disease. 2019 Mar 1
6 31209508 PON1 increases cellular DNA damage by lactone substrates. 2019 Jul 3
7 31351988 The epigenetic regulation of paraoxonase 1 (PON1) as an important enzyme in HDL function: The missing link between environmental and genetic regulation. 2019 Nov 2
8 29237378 Substrates for Paraoxonase. 2018 1
9 29404699 Paraoxonases: metabolic role and pharmacological projection. 2018 Apr 2
10 30241945 Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates. 2018 Oct 20 2
11 25982292 In vitro inhibition effect of some coumarin compounds on purified human serum paraoxonase 1 (PON1). 2016 Aug 2
12 25644661 Catalytic stimulation by restrained active-site floppiness--the case of high density lipoprotein-bound serum paraoxonase-1. 2015 Mar 27 1
13 26146888 Insights into the Lactonase Mechanism of Serum Paraoxonase 1 (PON1): Experimental and Quantum Mechanics/Molecular Mechanics (QM/MM) Studies. 2015 Jul 30 1
14 23788644 The evolutionary origins of detoxifying enzymes: the mammalian serum paraoxonases (PONs) relate to bacterial homoserine lactonases. 2013 Aug 16 1
15 21867409 The human paraoxonase gene cluster as a target in the treatment of atherosclerosis. 2012 Mar 15 1
16 22193970 Docking and molecular dynamics simulation studies on glycation-induced conformational changes of human paraoxonase 1. 2012 Feb 1
17 22387469 Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1. 2012 May 4 3
18 22577559 Novel associations of nonstructural Loci with paraoxonase activity. 2012 2
19 22971832 In vitro inhibition effect of some dihydroxy coumarin compounds on purified human serum paraoxonase 1 (PON1). 2012 Nov 2
20 21093416 Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on. 2011 Feb 1 1
21 19945920 Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1). 2010 May 15 4
22 20221874 Paraoxonase 1 attenuates human plaque atherogenicity: relevance to the enzyme lactonase activity. 2010 2
23 18971955 Determinants of variation in human serum paraoxonase activity. 2009 Feb 1
24 19764813 Dramatic differences in organophosphorus hydrolase activity between human and chimeric recombinant mammalian paraoxonase-1 enzymes. 2009 Nov 3 1
25 18572410 Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity. 2008 Aug 1 5
26 18711144 Engineered recombinant human paraoxonase 1 (rHuPON1) purified from Escherichia coli protects against organophosphate poisoning. 2008 Sep 2 2
27 19082953 Paraoxonases (PON1, PON2, PON3) analyses in vitro and in vivo in relation to cardiovascular diseases. 2008 1
28 16331452 High-level expression of recombinant human paraoxonase 1 Q in silkworm larvae (Bombyx mori). 2006 Aug 1
29 16595195 Tandem purification of two HDL-associated partner proteins in human plasma, paraoxonase (PON1) and phosphate binding protein (HPBP) using hydroxyapatite chromatography. 2006 May 19 1
30 15670573 Modulation of paraoxonase (PON1) activity. 2005 Feb 15 1
31 15835926 Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. 2005 Apr 26 5
32 16128586 High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I. 2005 Sep 6 2
33 12963475 Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3. 2003 Sep 15 3
34 11335891 Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. 2001 Jun 1