ICI D2788

cyclic nucleotide gated channel subunit alpha 1 ; Rattus norvegicus







51 Article(s)
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1 35008085 Decreased Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Activity in a Rat Model of Absence Epilepsy and the Effect of ZD7288, an Ih Inhibitor, on the Spike-and-Wave Discharges. 2022 1
2 35064517 Blockage of HCN Channels Inhibits the Function of P2X Receptors in Rat Dorsal Root Ganglion Neurons. 2022 Apr 2
3 35610006 Hyperpolarization-activated cyclic nucleotide-gated 2 contributes to electroacupuncture analgesia on lumbar disc herniation-induced radicular pain through activation of microglia in spinal dorsal horn. 2022 Jun 1
4 33995059 The HCN Channel Blocker ZD7288 Induces Emesis in the Least Shrew (Cryptotis parva). 2021 2
5 34845181 Moxibustion Regulates Gastrointestinal Motility via HCN1 in Functional Dyspepsia Rats. 2021 Nov 30 1
6 34948401 Lamotrigine Attenuates Neuronal Excitability, Depresses GABA Synaptic Inhibition, and Modulates Theta Rhythms in Rat Hippocampus. 2021 Dec 19 1
7 32248813 The impact of hyperpolarization-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium KCNQ/Kv7 channels on primary microglia function. 2020 Apr 6 1
8 30826524 Acupoint Sensitization is Associated with Increased Excitability and Hyperpolarization-Activated Current (Ih) in C- But Not Aδ-Type Neurons. 2019 Apr 15 1
9 30940440 HCN channel antagonist ZD7288 ameliorates neuropathic pain and associated depression. 2019 Aug 15 2
10 28801916 Adenosine and dopamine oppositely modulate a hyperpolarization-activated current Ih in chemosensory neurons of the rat carotid body in co-culture. 2018 Aug 1
11 29366880 Increased HCN Channel Activity in the Gasserian Ganglion Contributes to Trigeminal Neuropathic Pain. 2018 Jun 1
12 29806529 HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons. 2018 Jan-Dec 1
13 29925625 Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures. 2018 Jul 25 1
14 28166960 Effects of ZD7288, a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker, on term-pregnant rat uterine contractility in vitro. 2017 Mar 1 2
15 28469560 HCN Channel Modulation of Synaptic Integration in GABAergic Interneurons in Malformed Rat Neocortex. 2017 1
16 28673721 Contribution of presynaptic HCN channels to excitatory inputs of spinal substantia gelatinosa neurons. 2017 Sep 1 1
17 26855147 Neuropeptide S modulates the amygdaloidal HCN activities (Ih) in rats: Implication in chronic pain. 2016 Jun 1
18 27146984 HCN hyperpolarization-activated cation channels strengthen virtual nicotinic EPSPs and thereby elevate synaptic amplification in rat sympathetic neurons. 2016 Aug 1 1
19 27329413 Nucleus accumbens hyperpolarization-activated cyclic nucleotide-gated channels modulate methamphetamine self-administration in rats. 2016 Aug 3
20 27335562 ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. 2016 May 1
21 27542339 Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats. 2016 Sep 19 1
22 27807172 Nitric Oxide Modulates HCN Channels in Magnocellular Neurons of the Supraoptic Nucleus of Rats by an S-Nitrosylation-Dependent Mechanism. 2016 Nov 2 1
23 28219864 [Rebound depolarization of substantia gelatinosa neurons and its modulatory mechanisms in rat spinal dorsal horn]. 2016 Feb 20 1
24 24841085 HCN channels modulate the activity of the subthalamic nucleus in vivo. 2015 Jan 1
25 25677606 Changes in hyperpolarization-activated cyclic nucleotide-gated channel expression and activity in bladder interstitial cells of Cajal from rats with detrusor overactivity. 2015 Aug 1
26 25813712 Increased expression of HCN2 channel protein in L4 dorsal root ganglion neurons following axotomy of L5- and inflammation of L4-spinal nerves in rats. 2015 Jun 4 1
27 25858108 Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate firing of globus pallidus neurons in vivo. 2015 Sep 1
28 26400952 Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex. 2015 Sep 23 1
29 26709376 Characterization of the role of HCN channels in β3-adrenoceptor mediated rat bladder relaxation. 2015 2
30 24587682 ZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats. 2014 Feb 28 2
31 25042871 Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia. 2014 Dec 1
32 23219935 I(h) channels prevent overexcitability of early developmental CA1 neurons showing high input resistance in rats. 2013 Feb 2
33 23398435 Inhibition of HCN channels within the periaqueductal gray attenuates neuropathic pain in rats. 2013 Apr 1
34 23516351 Directional summation in non-direction selective retinal ganglion cells. 2013 1
35 23864381 Regulation of epileptiform discharges in rat neocortex by HCN channels. 2013 Oct 1
36 22446339 Identification of a hyperpolarization-activated cyclic nucleotide-gated channel and its subtypes in the urinary bladder of the rat. 2012 Jun 1
37 22792490 ZD7288 enhances long-term depression at early postnatal medial perforant path-granule cell synapses. 2012 2
38 21185265 HCN channel activity-dependent modulation of inhibitory synaptic transmission in the rat basolateral amygdala. 2011 Jan 28 1
39 20064502 ZD7288-induced suppression of long-term potentiation was attenuated by exogenous NMDA at the Schaffer collateral-CA1 synapse in the rat in vivo. 2010 Apr 10 2
40 20456426 Functional impact of the hyperpolarization-activated current on the excitability of myelinated A-type vagal afferent neurons in the rat. 2010 Aug 1
41 19322095 Intrathecal gabapentin does not act as a hyperpolarization-activated cyclic nucleotide-gated channel activator in the rat formalin test. 2009 Oct 1
42 18179873 Axonal accumulation of hyperpolarization-activated cyclic nucleotide-gated cation channels contributes to mechanical allodynia after peripheral nerve injury in rat. 2008 Jul 31 1
43 18513125 Septal infusions of the hyperpolarization-activated cyclic nucleotide-gated channel (HCN-channel) blocker ZD7288 impair spontaneous alternation but not inhibitory avoidance. 2008 Jun 2
44 18524809 Blunted excitability of aortic baroreceptor neurons in diabetic rats: involvement of hyperpolarization-activated channel. 2008 Sep 1 2
45 18850083 Presence of functional hyperpolarisation-activated cyclic nucleotide-gated channels in clonal alpha cell lines and rat islet alpha cells. 2008 Dec 4
46 17439493 Functional presynaptic HCN channels in the rat globus pallidus. 2007 Apr 2
47 17702809 alpha2-Noradrenergic receptors activation enhances excitability and synaptic integration in rat prefrontal cortex pyramidal neurons via inhibition of HCN currents. 2007 Oct 15 1
48 16765328 Characterization of hyperpolarization-activated current (Ih) in dorsal root ganglion neurons innervating rat urinary bladder. 2006 Jun 22 1
49 16307610 Synchronized network activity in developing rat hippocampus involves regional hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function. 2005 Nov 1
50 12598605 Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain. 2003 Feb 15 1