GW0742

peroxisome proliferator activated receptor delta ; Homo sapiens







31 Article(s)
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1 34387896 Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice. 2022 Jan 1
2 33426208 PPAR-δ agonist affects adipo-chondrogenic differentiation of human mesenchymal stem cells through the expression of PPAR-γ. 2020 Dec 1
3 29287957 Novel VDR antagonists based on the GW0742 scaffold. 2018 Feb 1 1
4 29621036 Comparative Evaluation of Gemcabene and Peroxisome Proliferator-Activated Receptor Ligands in Transcriptional Assays of Peroxisome Proliferator-Activated Receptors: Implication for the Treatment of Hyperlipidemia and Cardiovascular Disease. 2018 Jul 1
5 28825467 Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold. 2017 Oct 9 4
6 28901183 PPAR-δ Agonist With Mesenchymal Stem Cells Induces Type II Collagen-Producing Chondrocytes in Human Arthritic Synovial Fluid. 2017 Aug 1
7 29208022 Role of endoplasmic reticulum stress in the protective effects of PPARβ/δ activation on endothelial dysfunction induced by plasma from patients with lupus. 2017 Dec 6 2
8 26206209 The PPARβ/δ Agonist GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons: Role of PPARβ/δ in Neuronal Maturation. 2016 Mar 4
9 26768366 Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) activates promyogenic signaling pathways, thereby promoting myoblast differentiation. 2016 Jan 29 1
10 24352213 Telmisartan activates endogenous peroxisome proliferator-activated receptor-δ and may have anti-fibrotic effects in human mesangial cells. 2014 May 2
11 24486703 PPARδ activation inhibits homocysteine-induced p22(phox) expression in EA.hy926 cells through reactive oxygen species/p38MAPK pathway. 2014 Mar 15 1
12 24939361 The PPARβ/δ agonist GW0742 modulates signaling pathways associated with cardiac myocyte growth via a non-genomic redox mechanism. 2014 Oct 2
13 25485183 Modulation of Transcription mediated by the Vitamin D Receptor and the Peroxisome Proliferator-Activated Receptor δ in the presence of GW0742 analogs. 2014 2
14 22945906 Peroxisome proliferator-activated receptor delta agonist attenuates nicotine suppression effect on human mesenchymal stem cell-derived osteogenesis and involves increased expression of heme oxygenase-1. 2013 Jan 1
15 23915387 A selective peroxisome proliferator-activated receptor-β/δ agonist attenuates neointimal hyperplasia after wire-mediated arterial injury. 2013 Sep 1
16 23943160 Ligand-activated peroxisome proliferator-activated receptor β/δ modulates human endometrial cancer cell survival. 2013 Dec 2
17 24294133 Transcriptional regulation of Δ6-desaturase by peroxisome proliferative-activated receptor δ agonist in human pancreatic cancer cells: role of MEK/ERK1/2 pathway. 2013 1
18 22606221 Structural insights into human peroxisome proliferator activated receptor delta (PPAR-delta) selective ligand binding. 2012 6
19 22977012 Detection of PPARδ agonists GW1516 and GW0742 and their metabolites in human urine. 2012 Oct 2
20 21426320 Generation and characterization of a humanized PPARδ mouse model. 2011 Sep 1
21 19906781 Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway. 2010 Feb 1
22 20066433 PPARbeta activation inhibits melanoma cell proliferation involving repression of the Wilms' tumour suppressor WT1. 2010 Apr 1
23 18003597 PPARalpha and PPARbeta are differentially affected by ethanol and the ethanol metabolite acetaldehyde in the MCF-7 breast cancer cell line. 2008 Mar 2
24 18048767 Suppression of pro-inflammatory adhesion molecules by PPAR-delta in human vascular endothelial cells. 2008 Feb 1
25 18054822 Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines. 2008 Jan 14 1
26 18337495 PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. 2008 Mar 18 1
27 18687807 Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes. 2008 Nov 1
28 17254750 Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. 2007 Jun 1
29 16239641 Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts. 2006 Feb 1
30 15793256 Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta. 2005 Apr 1
31 12699745 Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity. 2003 May 5 1