Memantine

glutamate receptor, ionotropic, NMDA1 (zeta 1) ; Mus musculus







45 Article(s)
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1 35453065 Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease. 2022 Jun 5 2
2 33500723 Activation of N-methyl-D-aspartate receptor regulates insulin sensitivity and lipid metabolism. 2021 1
3 33882517 Memantine Alleviates Acute Lung Injury Via Inhibiting Macrophage Pyroptosis. 2021 Dec 1 1
4 33915770 Novel Mechanism for Memantine in Attenuating Diabetic Neuropathic Pain in Mice via Downregulating the Spinal HMGB1/TRL4/NF-kB Inflammatory Axis. 2021 Apr 1 1
5 34131204 Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct. 2021 Jun 15 1
6 34474083 Astrocytic Kir4.1 regulates NMDAR/calpain signaling axis in lipopolysaccharide-induced depression-like behaviors in mice. 2021 Oct 15 2
7 34594187 Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice. 2021 3
8 34646371 Upregulated NMDAR-mediated GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice. 2021 3
9 32860269 Fetal growth restriction mice are more likely to exhibit depression-like behaviors due to stress-induced loss of dopaminergic neurons in the VTA. 2020 Oct 1
10 30466882 Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice. 2019 Apr 1 3
11 30845688 Effects of Memantine in a Mouse Model of Postoperative Cognitive Dysfunction. 2019 Mar 6 2
12 31308798 Memantine Improves Cognitive Function and Alters Hippocampal and Cortical Proteome in Triple Transgenic Mouse Model of Alzheimer's Disease. 2019 Jun 2
13 31682950 Memantine Mitigates Oligodendrocyte Damage after Repetitive Mild Traumatic Brain Injury. 2019 Nov 21 1
14 28412305 Memantine improves outcomes after repetitive traumatic brain injury. 2018 Mar 15 1
15 29913137 Memantine rescues prenatal citalopram exposure-induced striatal and social abnormalities in mice. 2018 Sep 1
16 30293574 N-methyl-D-aspartate receptor-mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease. 2018 Oct 2
17 28303894 An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes. 2017 Mar 17 1
18 29112047 Memantine, an NMDA Receptor Antagonist, Prevents Thyroxin-induced Hypertension, but Not Cardiac Remodeling. 2017 Nov 2
19 26374431 Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model. 2016 Jan 3
20 26920629 Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia. 2016 Apr 1 2
21 27423317 Cytokine regulation by modulation of the NMDA receptor on astrocytes. 2016 Aug 26 1
22 25899790 Aggression and increased glutamate in the mPFC during withdrawal from intermittent alcohol in outbred mice. 2015 Aug 1
23 25942563 NMDA Receptor Antagonist Attenuates Bleomycin-Induced Acute Lung Injury. 2015 1
24 25974188 Involvement of NMDA glutamate receptors in the acquisition and reinstatement of the conditioned place preference induced by MDMA. 2015 Aug 1
25 26074764 Suppression of NMDA receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors. 2015 1
26 26089779 Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype. 2015 2
27 26301823 CIH-induced neurocognitive impairments are associated with hippocampal Ca(2+) overload, apoptosis, and dephosphorylation of ERK1/2 and CREB that are mediated by overactivation of NMDARs. 2015 Nov 2 1
28 26609150 Glutamate Receptors within the Mesolimbic Dopamine System Mediate Alcohol Relapse Behavior. 2015 Nov 25 1
29 24240127 The combination of glutamate receptor antagonist MK-801 with tamoxifen and its active metabolites potentiates their antiproliferative activity in mouse melanoma K1735-M2 cells. 2014 Feb 15 1
30 24269729 Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice. 2014 Feb 1
31 24344200 Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells. 2014 Mar 1
32 24937439 Nandrolone-induced aggressive behavior is associated with alterations in extracellular glutamate homeostasis in mice. 2014 Jul 1
33 22119002 Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo. 2012 Jan 11 1
34 22668780 Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice. 2012 Oct 1
35 20577261 Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells. 2011 Jan 1
36 21705496 Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions. 2011 Aug 18 1
37 18843265 Effects of topiramate and other anti-glutamatergic drugs on the acute intoxicating actions of ethanol in mice: modulation by genetic strain and stress. 2009 May 2
38 19154422 Pharmacological characterization of recombinant NR1/NR2A NMDA receptors with truncated and deleted carboxy termini expressed in Xenopus laevis oocytes. 2009 Feb 1
39 19361551 Stress exacerbates neuropathic pain via glucocorticoid and NMDA receptor activation. 2009 Aug 2
40 19915593 Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. 2009 Dec 1
41 17700645 Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test. 2008 Jun 2
42 18486118 Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone. 2008 Jun 18 1
43 18828800 Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine. 2008 Dec 1
44 16859831 Conantokins and variants derived from cone snail venom inhibit naloxone-induced withdrawal jumping in morphine-dependent mice. 2006 Sep 11 1
45 8886398 Effects of memantine on recombinant rat NMDA receptors expressed in HEK 293 cells. 1996 Sep 1