Adenosine Triphosphate

ATP binding cassette subfamily C member 8 ; Homo sapiens







117 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 18416191 [Physiological properties and possible correction of adenosine triphosphate-sensitive potassium channel function]. 2008 1
52 18679166 Sulfonylurea receptor 1 in the germinal matrix of premature infants. 2008 Dec 2
53 18691054 Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development. 2008 1
54 17395632 The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits. 2007 Jun 15 5
55 17451083 Congenital hyperinsulinism in an infant caused by a macroscopic insulin-producing lesion. 2007 Mar 2
56 17510180 Remodelling of the SUR-Kir6.2 interface of the KATP channel upon ATP binding revealed by the conformational blocker rhodamine 123. 2007 Jul 1 6
57 17522836 Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. 2007 Aug 1
58 17919182 beta-cell hyperexcitability: from hyperinsulinism to diabetes. 2007 Nov 4
59 18025464 Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes. 2007 Nov 27 2
60 16339180 Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels. 2006 Feb 15 5
61 16373383 ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2. 2006 Mar 1 1
62 16550187 Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. 2006 Apr 3
63 16556760 Minireview: pharmacogenetics and beyond: the interaction of therapeutic response, beta-cell physiology, and genetics in diabetes. 2006 Jun 2
64 16613899 A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes. 2006 Jun 1 1
65 16885549 Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. 2006 Aug 3 1
66 16936192 ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells. 2006 Sep 1
67 17296510 Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: therapeutic consequences. 2006 Dec 1
68 15811927 Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels. 2005 Jul 1
69 15893323 Differential nucleotide regulation of KATP channels by SUR1 and SUR2A. 2005 Sep 1
70 15978900 A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K(+) channels. 2005 Jul 1
71 15978902 Function and distribution of the SUR isoforms and splice variants. 2005 Jul 2
72 15998776 Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function. 2005 Sep 1
73 16308567 3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1. 2005 Dec 7 1
74 14699091 Assembly, maturation, and turnover of K(ATP) channel subunits. 2004 Mar 5 3
75 14707124 Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor. 2004 Mar 19 2
76 15004210 Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2. 2004 Jun 1 3
77 15501029 2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K(ATP) channels. 2004 Dec 6 1
78 15561922 Integration of ATP, cAMP, and Ca2+ signals in insulin granule exocytosis. 2004 Dec 3
79 12941782 Clinical and molecular characterization of a dominant form of congenital hyperinsulinism caused by a mutation in the high-affinity sulfonylurea receptor. 2003 Sep 3
80 14561820 Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP inhibition of KATP channels by the same mechanism. 2003 Oct 15 1
81 11924895 SURI and Kir6.1 subunits of K(ATP)-channels are co-localized in retinal glial (Müller) cells. 2002 Jan 21 2
82 12031979 The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener. 2002 Jun 1
83 12145099 Glibenclamide binding to sulphonylurea receptor subtypes: dependence on adenine nucleotides. 2002 Aug 6
84 12213829 SUR-dependent modulation of KATP channels by an N-terminal KIR6.2 peptide. Defining intersubunit gating interactions. 2002 Nov 15 1
85 11418131 Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel. 2001 Jun 15 2
86 11502255 Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance. 2001 Aug 2 1
87 11585851 Regulation of cloned ATP-sensitive K channels by adenine nucleotides and sulfonylureas: interactions between SUR1 and positively charged domains on Kir6.2. 2001 Oct 5
88 11673467 A conserved inhibitory and differential stimulatory action of nucleotides on K(IR)6.0/SUR complexes is essential for excitation-metabolism coupling by K(ATP) channels. 2001 Dec 28 2
89 10615958 Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy: nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1. 2000 Jan 5
90 10625598 Pharmaco-topology of sulfonylurea receptors. Separate domains of the regulatory subunits of K(ATP) channel isoforms are required for selective interaction with K(+) channel openers. 2000 Jan 14 1
91 10864893 Sensitivity of Kir6.2-SUR1 currents, in the absence and presence of sodium azide, to the K(ATP) channel inhibitors, ciclazindol and englitazone. 2000 Jun 2
92 10956638 Hetero-concatemeric KIR6.X4/SUR14 channels display distinct conductivities but uniform ATP inhibition. 2000 Oct 13 1
93 10962016 Regulation of cloned ATP-sensitive K channels by phosphorylation, MgADP, and phosphatidylinositol bisphosphate (PIP(2)): a study of channel rundown and reactivation. 2000 Sep 3
94 10990455 A region of the sulfonylurea receptor critical for a modulation of ATP-sensitive K(+) channels by G-protein betagamma-subunits. 2000 Sep 15 3
95 10993895 Functional analysis of a mutant sulfonylurea receptor, SUR1-R1420C, that is responsible for persistent hyperinsulinemic hypoglycemia of infancy. 2000 Dec 29 3
96 11018523 Investigation of the molecular assembly of beta-cell K(ATP) channels. 2000 Sep 29 1
97 11073882 C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels. 2000 Nov 10 1
98 9925874 ATP inhibition of KATP channels: control of nucleotide sensitivity by the N-terminal domain of the Kir6.2 subunit. 1999 Feb 15 4
99 9990013 Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. 1999 Feb 16 4
100 10069387 Sulfonylurea receptors set the maximal open probability, ATP sensitivity and plasma membrane density of KATP channels. 1999 Feb 19 2