| 1 |
34380876 | The short form of the SUR1 and its functional implications in the damaged brain. | 2022 Mar |
2 |
| 2 |
35434386 | Inward and outward currents of native and cloned K(ATP) channels (Kir6.2/SUR1) share single-channel kinetic properties. | 2022 Jul |
1 |
| 3 |
33627316 | Glucolipotoxicity and GLP-1 secretion. | 2021 Feb |
1 |
| 4 |
34766906 | Lactate is an energy substrate for rodent cortical neurons and enhances their firing activity. | 2021 Nov 12 |
1 |
| 5 |
31909710 | Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry. | 2020 Jan 7 |
1 |
| 6 |
32376986 | New insights into KATP channel gene mutations and neonatal diabetes mellitus. | 2020 Jul |
2 |
| 7 |
29737232 | Kir6.2, the Pore-Forming Subunit of ATP-Sensitive K+ Channels, Is Overexpressed in Human Posttraumatic Brain Contusions. | 2019 Jan 1 |
2 |
| 8 |
30587573 | ATP binding without hydrolysis switches sulfonylurea receptor 1 (SUR1) to outward-facing conformations that activate KATP channels. | 2019 Mar 8 |
20 |
| 9 |
30861254 | Functional characterization of activating mutations in the sulfonylurea receptor 1 (ABCC8) causing neonatal diabetes mellitus in Asian Indian children. | 2019 Jun |
4 |
| 10 |
31067468 | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel. | 2019 May 7 |
1 |
| 11 |
31588541 | Monogenic Forms of Diabetes Mellitus. | 2019 |
1 |
| 12 |
31814333 | The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel. | 2019 Dec |
1 |
| 13 |
29685928 | Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels. | 2018 May 7 |
1 |
| 14 |
28092267 | Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating. | 2017 Jan 16 |
3 |
| 15 |
29035201 | Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM. | 2017 Oct 24 |
2 |
| 16 |
29286281 | Molecular structure of human KATP in complex with ATP and ADP. | 2017 Dec 29 |
2 |
| 17 |
25926814 | Neonatal Diabetes and Congenital Hyperinsulinism Caused by Mutations in ABCC8/SUR1 are Associated with Altered and Opposite Affinities for ATP and ADP. | 2015 |
4 |
| 18 |
25934393 | A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels. | 2015 Jun 19 |
1 |
| 19 |
26682803 | The Nucleotide-Binding Sites of SUR1: A Mechanistic Model. | 2015 Dec 15 |
1 |
| 20 |
25143473 | The insulin-sensitivity sulphonylurea receptor variant is associated with thyrotoxic paralysis. | 2014 Oct |
1 |
| 21 |
25153533 | Successful development and use of a thermodynamic stability screen for optimizing the yield of nucleotide binding domains. | 2014 Nov |
1 |
| 22 |
23275527 | Genotype and phenotype correlations in 417 children with congenital hyperinsulinism. | 2013 Feb |
1 |
| 23 |
23665564 | Reinterpreting the action of ATP analogs on K(ATP) channels. | 2013 Jun 28 |
3 |
| 24 |
23695995 | Engineered Kir6.2 mutations that correct the trafficking defect of K(ATP) channels caused by specific SUR1 mutations. | 2013 Jul-Aug |
3 |
| 25 |
22083559 | Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic K(ATP) channel. | 2012 Mar |
2 |
| 26 |
22125096 | Novel treatment targets for cerebral edema. | 2012 Jan |
2 |
| 27 |
22451668 | Two neonatal diabetes mutations on transmembrane helix 15 of SUR1 increase affinity for ATP and ADP at nucleotide binding domain 2. | 2012 May 25 |
3 |
| 28 |
22562119 | Compound heterozygous mutations in the SUR1 (ABCC 8) subunit of pancreatic K(ATP) channels cause neonatal diabetes by perturbing the coupling between Kir6.2 and SUR1 subunits. | 2012 Mar-Apr |
1 |
| 29 |
22714048 | Sulfonylurea receptor 1 in central nervous system injury: a focused review. | 2012 Sep |
2 |
| 30 |
22802363 | Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels. | 2012 Aug |
6 |
| 31 |
22802590 | A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening. | 2012 Oct 15 |
2 |
| 32 |
23078514 | NMR and fluorescence studies of drug binding to the first nucleotide binding domain of SUR2A. | 2012 Nov 13 |
1 |
| 33 |
21173146 | ATP modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic beta-cell KATP channels. | 2011 Feb 18 |
6 |
| 34 |
21321069 | N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. | 2011 Mar |
5 |
| 35 |
21540348 | A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated. | 2011 Jul 1 |
1 |
| 36 |
21617188 | Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes. | 2011 Jun |
1 |
| 37 |
21654216 | ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity. | 2011 Jul-Aug |
5 |
| 38 |
22020219 | Mechanism of KATP hyperactivity and sulfonylurea tolerance due to a diabetogenic mutation in L0 helix of sulfonylurea receptor 1 (ABCC8). | 2011 Nov 16 |
1 |
| 39 |
19919106 | Chloro-substituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity. | 2010 Jan 14 |
1 |
| 40 |
20033705 | Human K(ATP) channelopathies: diseases of metabolic homeostasis. | 2010 Jul |
2 |
| 41 |
20876358 | Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1. | 2010 Oct |
4 |
| 42 |
23226049 | The molecular mechanisms and pharmacotherapy of ATP-sensitive potassium channel gene mutations underlying neonatal diabetes. | 2010 |
6 |
| 43 |
19139106 | Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: differences between the channel subtypes formed with SUR1. | 2009 Mar 13 |
2 |
| 44 |
19151370 | Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure. | 2009 Mar 20 |
2 |
| 45 |
19587354 | Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel. | 2009 Oct |
1 |
| 46 |
19766903 | Metabolic control in type 2 diabetes is associated with sulfonylurea receptor-1 (SUR-1) but not with KCNJ11 polymorphisms. | 2009 Jul |
2 |
| 47 |
20049716 | Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism. | 2009 Jun |
1 |
| 48 |
18231807 | Dual regulation of the ATP-sensitive potassium channel by activation of cGMP-dependent protein kinase. | 2008 Aug |
1 |
| 49 |
18281290 | A novel ABCC8 (SUR1)-dependent mechanism of metabolism-excitation uncoupling. | 2008 Apr 4 |
3 |
| 50 |
18346985 | A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults. | 2008 Jun |
1 |