Sulfonylurea Compounds

ATP binding cassette subfamily C member 8 ; Homo sapiens







112 Article(s)
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51 23502672 Clinical profile and outcome of infantile onset diabetes mellitus in southern India. 2013 Aug 1
52 24324494 Pharmacogenetics of oral antidiabetic drugs. 2013 3
53 21989597 Heterozygous ABCC8 mutations are a cause of MODY. 2012 Jan 3
54 22118705 Treating diabetes today: a matter of selectivity of sulphonylureas. 2012 Jan 1
55 22433315 Cardiovascular effects of antidiabetic agents: focus on blood pressure effects of incretin-based therapies. 2012 May-Jun 1
56 22533711 ABCC8 polymorphisms are associated with triglyceride concentration in type 2 diabetics on sulfonylurea therapy. 2012 Aug 6
57 22768668 Improved long-term glucose control in neonatal diabetes mellitus after early sulfonylurea allergy. 2012 1
58 22842804 Successful sulfonylurea treatment of a neonate with neonatal diabetes mellitus due to a novel missense mutation, p.P1199L, in the ABCC8 gene. 2012 Aug 1
59 22996131 Monogenic models: what have the single gene disorders taught us? 2012 Dec 1
60 21109997 Successful transfer to sulfonylurea therapy in an infant with developmental delay, epilepsy and neonatal diabetes (DEND) syndrome and a novel ABCC8 gene mutation. 2011 Feb 1
61 21273495 The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes. 2011 Mar 1
62 21796147 A pathway to insulin independence in newborns and infants with diabetes. 2011 Aug 1
63 21993633 Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. 2011 Dec 1
64 22020219 Mechanism of KATP hyperactivity and sulfonylurea tolerance due to a diabetogenic mutation in L0 helix of sulfonylurea receptor 1 (ABCC8). 2011 Nov 16 3
65 22124439 Management of diabetes mellitus in infants. 2011 Nov 29 1
66 22308870 Transient neonatal diabetes with two novel mutations in the KCNJ11 gene and response to sulfonylurea treatment in a preterm infant. 2011 1
67 24843477 Genetics and pathophysiology of neonatal diabetes mellitus. 2011 Jun 5 1
68 21142918 ABCC8 polymorphism (Ser1369Ala): influence on severe hypoglycemia due to sulfonylureas. 2010 Dec 1
69 23226049 The molecular mechanisms and pharmacotherapy of ATP-sensitive potassium channel gene mutations underlying neonatal diabetes. 2010 2
70 19139106 Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: differences between the channel subtypes formed with SUR1. 2009 Mar 13 1
71 19323963 Pharmacogenetics in diabetes. 2009 Apr 2
72 19342262 Mutations in the ABCC8 gene can cause autoantibody-negative insulin-dependent diabetes. 2009 Jun 1
73 19587354 Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel. 2009 Oct 1
74 19799532 Influence of genetic polymorphisms on the pharmacokinetics and pharmaco-dynamics of sulfonylurea drugs. 2009 Jul 3
75 18025408 Effective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations. 2008 Feb 5
76 18032110 Drugs acting on SUR1 to treat CNS ischemia and trauma. 2008 Feb 1
77 18301398 Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes. 2008 Apr 1
78 17110465 Defining a binding pocket for sulfonylureas in ATP-sensitive potassium channels. 2007 Jan 3
79 17213273 Prevalence of permanent neonatal diabetes in Slovakia and successful replacement of insulin with sulfonylurea therapy in KCNJ11 and ABCC8 mutation carriers. 2007 Apr 1
80 17349054 Neonatal diabetes mellitus: a disease linked to multiple mechanisms. 2007 Mar 9 1
81 17575084 Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue. 2007 Sep 2
82 17931842 [Neonatal diabetes: a disease linked to multiple mechanisms]. 2007 Nov 1
83 17986830 Management of neonatal and infancy-onset diabetes mellitus. 2007 1
84 16556760 Minireview: pharmacogenetics and beyond: the interaction of therapeutic response, beta-cell physiology, and genetics in diabetes. 2006 Jun 1
85 16885549 Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. 2006 Aug 3 1
86 16956886 Sulfonylureas correct trafficking defects of disease-causing ATP-sensitive potassium channels by binding to the channel complex. 2006 Nov 3 4
87 17296510 Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: therapeutic consequences. 2006 Dec 1
88 15652236 Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas. 2005 Feb 1 2
89 15659079 Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients. 2005 Jan 2
90 14707124 Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor. 2004 Mar 19 3
91 15561897 Toward linking structure with function in ATP-sensitive K+ channels. 2004 Dec 2
92 12566087 Inhibition of ATP-sensitive K(+)-channels by a sulfonylurea analogue with a phosphate group. 2003 Feb 15 1
93 12879777 [Polymorphism of the sulfonylurea receptor gene in type 2 diabetes mellitus]. 2003 Feb 3
94 12939732 Ischemia in type 2 diabetes: tissue selectivity of sulfonylureas and clinical implications. 2003 Aug 2
95 11825905 Assembly limits the pharmacological complexity of ATP-sensitive potassium channels. 2002 Apr 19 1
96 12118200 Sulfonylurea receptor gene 16-3 polymorphism - association with sulfonylurea or insulin treatment in type 2 diabetic subjects. 2002 Jul 3
97 12475777 Sulfonylurea stimulation of insulin secretion. 2002 Dec 1
98 12703060 [Molecular mechanisms of insulin secretion]. 2002 Dec 1
99 11272143 Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations. 2001 Feb 1
100 11343328 Impact of sulfonylurea receptor 1 genetic variability on non-insulin-dependent diabetes mellitus prevalence and treatment: a population study. 2001 Jun 1 1