Glutathione

glutathione peroxidase 4 ; Homo sapiens







99 Article(s)
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1 33393679 Application of natural products for inducing ferroptosis in tumor cells. 2022 Feb 1
2 34592546 A cascaded copper-based nanocatalyst by modulating glutathione and cyclooxygenase-2 for hepatocellular carcinoma therapy. 2022 Feb 2
3 34710950 An ROS-Activatable Nanoassembly Remodulates Tumor Cell Metabolism for Enhanced Ferroptosis Therapy. 2022 Jan 2
4 34727409 MiR-15a-3p regulates ferroptosis via targeting glutathione peroxidase GPX4 in colorectal cancer. 2022 Mar 1
5 34762602 15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation. 2022 Jan 4 3
6 34775124 A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis. 2022 Jan 15 1
7 34905922 Glutathione-Responsive Chemodynamic Therapy of Manganese(III/IV) Cluster Nanoparticles Enhanced by Electrochemical Stimulation via Oxidative Stress Pathway. 2022 Jan 19 2
8 34936351 "Clickable" ZIF-8 for Cell-Type-Specific Delivery of Functional Proteins. 2022 Jan 21 1
9 34983546 CRISPR screens uncover protective effect of PSTK as a regulator of chemotherapy-induced ferroptosis in hepatocellular carcinoma. 2022 Jan 4 1
10 35050181 Abnormal Iron and Lipid Metabolism Mediated Ferroptosis in Kidney Diseases and Its Therapeutic Potential. 2022 Jan 10 3
11 35062064 Association of genetic variants in the GPX1 and GPX4 genes with the activities of glutathione-dependent enzymes, their interaction with smoking and the risk of acute pancreatitis. 2022 Feb 1
12 35102454 Role of Ferroptosis in Stroke. 2022 Jan 31 1
13 35104766 Ponicidin suppresses pancreatic cancer growth by inducing ferroptosis: Insight gained by mass spectrometry-based metabolomics. 2022 Jan 14 1
14 35107212 Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal. 2022 Feb 2 4
15 35128925 Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1). 2022 Feb 18 2
16 35148992 Expression of gamma-glutamyltransferase 1 in glioblastoma cells confers resistance to cystine deprivation-induced ferroptosis. 2022 Mar 1
17 35275790 Epstein-Barr virus latency programs dynamically sensitize B cells to ferroptosis. 2022 Mar 15 1
18 35306372 Live cell imaging of oxidative stress in human airway epithelial cells exposed to isoprene hydroxyhydroperoxide. 2022 May 1
19 35337799 Monitoring the induction of ferroptosis following dissociation in human embryonic stem cells. 2022 May 1
20 35434035 The critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review. 2022 Mar 4
21 35489546 Rapid synthesis of 'yolk-shell'-like nanosystem for MR molecular and chemo-radio sensitization. 2022 May 5 2
22 35581292 Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis. 2022 May 17 1
23 35585057 Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis. 2022 May 18 2
24 35605092 Function and regulation of GPX4 in the development and progression of fibrotic disease. 2022 May 23 2
25 32804006 Ferroptosis: machinery and regulation. 2021 Sep 1
26 33172933 Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis. 2021 Jan 15 2
27 33260096 Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors. 2021 Jan 2
28 33372514 Dual-Responsive and Deep-Penetrating Nanomicelles for Tumor Therapy via Extracellular Matrix Degradation and Oxidative Stress. 2021 Jan 11 2
29 33377232 Identification and initial characterization of a potent inhibitor of ferroptosis. 2021 Apr 4
30 33421769 Role of ferritinophagy in cystine deprivation-induced cell death in glioblastoma cells. 2021 Feb 5 2
31 33462411 Cellular degradation systems in ferroptosis. 2021 Apr 1
32 33495834 Ferroptosis in hepatic ischemia‑reperfusion injury: Regulatory mechanisms and new methods for therapy (Review). 2021 Mar 1
33 33603367 Co-Administration of iRGD with Sorafenib-Loaded Iron-Based Metal-Organic Framework as a Targeted Ferroptosis Agent for Liver Cancer Therapy. 2021 1
34 33707434 mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. 2021 Mar 11 4
35 33711415 Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion. 2021 May 1 1
36 33746607 Ammonium Ferric Citrate induced Ferroptosis in Non-Small-Cell Lung Carcinoma through the inhibition of GPX4-GSS/GSR-GGT axis activity. 2021 1
37 33917880 Cold Atmospheric Plasma Increases Temozolomide Sensitivity of Three-Dimensional Glioblastoma Spheroids via Oxidative Stress-Mediated DNA Damage. 2021 Apr 8 2
38 34048148 Lipoxin A4 protects primary spinal cord neurons from Erastin-induced ferroptosis by activating the Akt/Nrf2/HO-1 signaling pathway. 2021 May 28 1
39 34092035 Signaling pathways and defense mechanisms of ferroptosis. 2021 Jun 6 1
40 34102574 Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes. 2021 Sep 2
41 34127539 Thermal Proteome Profiling Reveals Glutathione Peroxidase 4 as the Target of the Autophagy Inducer Conophylline. 2021 Sep 1
42 34167028 A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO• sabotage of theft-ferroptosis. 2021 Sep 2
43 34169392 ZEB1 directly inhibits GPX4 transcription contributing to ROS accumulation in breast cancer cells. 2021 Jul 1
44 34238297 Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy. 2021 Jul 8 2
45 34350694 The Sustainability of Energy Conversion Inhibition for Tumor Ferroptosis Therapy and Chemotherapy. 2021 Sep 1
46 34360557 Expression Silencing of Glutathione Peroxidase 4 in Mouse Erythroleukemia Cells Delays In Vitro Erythropoiesis. 2021 Jul 21 2
47 34448349 Functionalized Tumor-Targeting Nanosheets Exhibiting Fe(II) Overloading and GSH Consumption for Ferroptosis Activation in Liver Tumor. 2021 Oct 6
48 34535975 pH-Sensitive Molecular-Switch-Containing Polymer Nanoparticle for Breast Cancer Therapy with Ferritinophagy-Cascade Ferroptosis and Tumor Immune Activation. 2021 Nov 2
49 34586745 Glutathione peroxidase 4-dependent glutathione high-consumption drives acquired platinum chemoresistance in lung cancer-derived brain metastasis. 2021 Sep 5
50 34623415 Ferroptosis and NRF2: an emerging battlefield in the neurodegeneration of Alzheimer's disease. 2021 Dec 22 2