| 1 |
34775124 | A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis. | 2022 Jan 15 |
2 |
| 2 |
34800783 | The molecular mechanisms of ferroptosis and its role in cardiovascular disease. | 2022 Jan |
1 |
| 3 |
35128925 | Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1). | 2022 Feb 18 |
2 |
| 4 |
35306372 | Live cell imaging of oxidative stress in human airway epithelial cells exposed to isoprene hydroxyhydroperoxide. | 2022 May |
1 |
| 5 |
35453406 | A Genotype-Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation. | 2022 Apr 6 |
2 |
| 6 |
35484753 | Tumor Microenvironment-Responsive Nanodrug for Clear-Cell Renal Cell Carcinoma Therapy via Triggering Waterfall-Like Cascade Ferroptosis. | 2022 Feb 1 |
4 |
| 7 |
35523770 | The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells. | 2022 May 6 |
3 |
| 8 |
35551311 | Multi-pathway inducing ferroptosis by MnO2-based nanodrugs for targeted cancer therapy. | 2022 Jun 1 |
1 |
| 9 |
35568865 | A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin. | 2022 May 14 |
4 |
| 10 |
35614872 | Ferroptosis-Driven Nanotherapeutics to Reverse Drug Resistance in Tumor Microenvironment. | 2022 Jun 20 |
2 |
| 11 |
35637349 | Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability. | 2022 May 30 |
1 |
| 12 |
33260096 | Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors. | 2021 Jan |
2 |
| 13 |
34007410 | Positive and Negative Regulation of Ferroptosis and Its Role in Maintaining Metabolic and Redox Homeostasis. | 2021 |
1 |
| 14 |
34127539 | Thermal Proteome Profiling Reveals Glutathione Peroxidase 4 as the Target of the Autophagy Inducer Conophylline. | 2021 Sep |
2 |
| 15 |
34133924 | The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. | 2021 Jun 15 |
2 |
| 16 |
34360557 | Expression Silencing of Glutathione Peroxidase 4 in Mouse Erythroleukemia Cells Delays In Vitro Erythropoiesis. | 2021 Jul 21 |
2 |
| 17 |
34492183 | Electrostatic Drivers of GPx4 Interactions with Membrane, Lipids, and DNA. | 2021 Sep 21 |
2 |
| 18 |
34535975 | pH-Sensitive Molecular-Switch-Containing Polymer Nanoparticle for Breast Cancer Therapy with Ferritinophagy-Cascade Ferroptosis and Tumor Immune Activation. | 2021 Nov |
2 |
| 19 |
31065106 | Liver stage malaria infection is controlled by host regulators of lipid peroxidation. | 2020 Jan |
1 |
| 20 |
31574461 | Insight into the mechanism of ferroptosis inhibition by ferrostatin-1. | 2020 Jan |
1 |
| 21 |
32061663 | Where ferroptosis inhibitors and paraquat detoxification mechanisms intersect, exploring possible treatment strategies. | 2020 Mar 30 |
2 |
| 22 |
32165281 | Lipid peroxidation and ferroptosis: The role of GSH and GPx4. | 2020 May 20 |
1 |
| 23 |
32945131 | Near Infrared-Activatable Platinum-Decorated Gold Nanostars for Synergistic Photothermal/Ferroptotic Therapy in Combating Cancer Drug Resistance. | 2020 Oct |
1 |
| 24 |
33087576 | PLA2G6 guards placental trophoblasts against ferroptotic injury. | 2020 Nov 3 |
1 |
| 25 |
30289974 | Reduced expression of the ferroptosis inhibitor glutathione peroxidase-4 in multiple sclerosis and experimental autoimmune encephalomyelitis. | 2019 Feb |
2 |
| 26 |
30888116 | GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis. | 2019 Sep |
2 |
| 27 |
29515790 | Impact of glutathione peroxidase 4 on cell proliferation, angiogenesis and cytokine production in hepatocellular carcinoma. | 2018 Feb 9 |
2 |
| 28 |
27836545 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis. | 2017 Jan 8 |
1 |
| 29 |
28678785 | Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. | 2017 Jul 27 |
1 |
| 30 |
28972104 | The α6β4 integrin promotes resistance to ferroptosis. | 2017 Dec 4 |
2 |
| 31 |
25516417 | Glutathione peroxidase 4 is reversibly induced by HCV to control lipid peroxidation and to increase virion infectivity. | 2016 Jan |
1 |
| 32 |
27506793 | Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. | 2016 Aug 23 |
2 |
| 33 |
26042203 | Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. | 2015 Jun |
2 |
| 34 |
22105228 | Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. | 2012 Apr |
2 |
| 35 |
22433871 | Oxidatively truncated phospholipids are required agents of tumor necrosis factor α (TNFα)-induced apoptosis. | 2012 May 18 |
2 |
| 36 |
22446825 | Characterization of phospholipid hydroperoxide glutathione metabolizing peroxidase (gpx4) isoforms in Coho salmon olfactory and liver tissues and their modulation by cadmium. | 2012 Jun 15 |
1 |
| 37 |
20649470 | A comparison of thiol peroxidase mechanisms. | 2011 Aug 1 |
1 |
| 38 |
19769463 | Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease. | 2010 Apr 1 |
1 |
| 39 |
19808099 | Molecular characterization of a phospholipid-hydroperoxide glutathione peroxidase from the bumblebee Bombus ignitus. | 2010 Jan |
1 |
| 40 |
20798033 | 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases. | 2010 Sep 7 |
1 |
| 41 |
19376195 | Catalytic mechanisms and specificities of glutathione peroxidases: variations of a basic scheme. | 2009 Nov |
1 |
| 42 |
18723092 | New strategies for the isolation and activity determination of naturally occurring type-4 glutathione peroxidase. | 2008 Dec |
4 |
| 43 |
17431126 | Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity. | 2007 Apr |
2 |
| 44 |
17516241 | Phospholipid hydroperoxide glutathione peroxidase (PHGPx) expression is downregulated in poorly differentiated breast invasive ductal carcinoma. | 2007 Jun |
2 |
| 45 |
17630701 | Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4). | 2007 Aug 7 |
1 |
| 46 |
16409129 | Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase. | 2006 Jan |
3 |
| 47 |
17020817 | Phospholipid-hydroperoxide glutathione peroxidase (GPx-4) localization in resting platelets, and compartmental change during platelet activation. | 2006 Oct |
2 |
| 48 |
16181973 | PHGPx in spermatogenesis: how many functions? | 2005 Oct |
2 |
| 49 |
15256721 | Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor. | 2004 Jul |
3 |
| 50 |
15280629 | Implications of oxidative stress and cell membrane lipid peroxidation in human cancer (Spain). | 2004 Sep |
2 |