| 1 |
32937226 | Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications. | 2021 Apr |
1 |
| 2 |
33303629 | Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2). | 2021 Jan-Jun |
1 |
| 3 |
33517899 | High GFPT1 expression predicts unfavorable outcomes in patients with resectable pancreatic ductal adenocarcinoma. | 2021 Jan 31 |
2 |
| 4 |
33897873 | Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. | 2021 |
1 |
| 5 |
33916835 | High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer's Disease Signatures. | 2021 Apr 3 |
1 |
| 6 |
34291417 | FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells. | 2021 Nov |
1 |
| 7 |
34951587 | Hyaluronic acid fuels pancreatic cancer cell growth. | 2021 Dec 24 |
2 |
| 8 |
32019926 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. | 2020 Feb 4 |
2 |
| 9 |
33278716 | Reprint of: Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications. | 2020 Oct |
1 |
| 10 |
30305725 | IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells. | 2019 Feb |
2 |
| 11 |
30635494 | Leukoencephalopathy due to variants in GFPT1-associated congenital myasthenic syndrome. | 2019 Feb 5 |
1 |
| 12 |
29753740 | 2-Deoxy-d-glucose increases GFAT1 phosphorylation resulting in endoplasmic reticulum-related apoptosis via disruption of protein N-glycosylation in pancreatic cancer cells. | 2018 Jun 27 |
2 |
| 13 |
30201609 | mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation. | 2018 Oct 19 |
3 |
| 14 |
28008135 | GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis. | 2017 Mar 7 |
1 |
| 15 |
28319096 | Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway. | 2017 Mar 20 |
2 |
| 16 |
28336748 | The sweet side of AMPK signaling: regulation of GFAT1. | 2017 Mar 23 |
2 |
| 17 |
28423621 | Epstein-Barr virus encoded microRNA BART7 regulates radiation sensitivity of nasopharyngeal carcinoma. | 2017 Mar 21 |
1 |
| 18 |
26887390 | Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis. | 2016 Jul |
2 |
| 19 |
27509259 | Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer. | 2016 Jun 21 |
2 |
| 20 |
27570073 | mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. | 2016 Sep 1 |
3 |
| 21 |
26501342 | Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1). | 2015 Oct 16 |
2 |
| 22 |
24075873 | Mapping the UDP-N-acetylglucosamine regulatory site of human glucosamine-6P synthase by saturation-transfer difference NMR and site-directed mutagenesis. | 2014 Feb |
1 |
| 23 |
23569079 | Mutations in GFPT1 that underlie limb-girdle congenital myasthenic syndrome result in reduced cell-surface expression of muscle AChR. | 2013 Jul 15 |
2 |
| 24 |
23767808 | Glutamine: fructose-6-phosphate amidotransferase (GFAT): homology modelling and designing of new inhibitors using pharmacophore and docking based hierarchical virtual screening protocol. | 2013 |
4 |
| 25 |
21374590 | Suppression of Glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes. | 2012 Jan |
2 |
| 26 |
22987706 | Limb-girdle myasthenia with tubular aggregates associated with novel GFPT1 mutations. | 2012 Oct |
2 |
| 27 |
21697645 | Glucosamine induces cell death via proteasome inhibition in human ALVA41 prostate cancer cell. | 2011 Sep 30 |
2 |
| 28 |
19903862 | Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux. | 2010 Feb |
2 |
| 29 |
17178709 | Glycosylation mediates up-regulation of a potent antiangiogenic and proatherogenic protein, thrombospondin-1, by glucose in vascular smooth muscle cells. | 2007 Feb 23 |
1 |
| 30 |
17574229 | Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stress. | 2007 Sep |
2 |
| 31 |
17941647 | Identification of a novel serine phosphorylation site in human glutamine:fructose-6-phosphate amidotransferase isoform 1. | 2007 Nov 13 |
3 |
| 32 |
17024311 | Effect of +36T>C in intron 1 on the glutamine: fructose-6-phosphate amidotransferase 1 gene and its contribution to type 2 diabetes in different populations. | 2006 |
2 |
| 33 |
15613432 | The -913 G/A glutamine:fructose-6-phosphate aminotransferase gene polymorphism is associated with measures of obesity and intramyocellular lipid content in nondiabetic subjects. | 2005 Mar |
2 |
| 34 |
16220784 | [Establishment of an IR-HIRc cell model for screening GFAT inhibitor]. | 2005 May |
1 |
| 35 |
14764791 | Common variants in glutamine:fructose-6-phosphate amidotransferase 2 (GFPT2) gene are associated with type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels. | 2004 Feb |
3 |
| 36 |
14988277 | Scrutiny of the glutamine-fructose-6-phosphate transaminase 1 (GFPT1) locus reveals conserved haplotype block structure not associated with diabetic nephropathy. | 2004 Mar |
2 |
| 37 |
12606504 | Palmitate-induced activation of the hexosamine pathway in human myotubes: increased expression of glutamine:fructose-6-phosphate aminotransferase. | 2003 Mar |
1 |
| 38 |
12679868 | P38 mitogen-activated protein kinase mediates hexosamine-induced TGFbeta1 mRNA expression in human mesangial cells. | 2003 Apr |
3 |
| 39 |
12802498 | Glutamine:fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells. | 2003 Jun |
2 |
| 40 |
11842094 | Kinetic characterization of human glutamine-fructose-6-phosphate amidotransferase I: potent feedback inhibition by glucosamine 6-phosphate. | 2002 Apr 26 |
2 |
| 41 |
11872372 | Hexosamines as mediators of nutrient sensing and regulation in diabetes. | 2002 Jan-Feb |
2 |
| 42 |
11916938 | Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation. | 2002 Apr |
3 |
| 43 |
11163803 | Overexpression of glutamine:fructose-6-phosphate-amidotransferase induces transforming growth factor-beta1 synthesis in NIH-3T3 fibroblasts. | 2001 Jan 12 |
2 |
| 44 |
11399656 | Angiotensin II activates the GFAT promoter in mesangial cells. | 2001 Jul |
2 |
| 45 |
11587069 | Identification of GFAT1-L, a novel splice variant of human glutamine: fructose-6-phosphate amidotransferase (GFAT1) that is expressed abundantly in skeletal muscle. | 2001 |
1 |
| 46 |
11679416 | A novel variant of glutamine: fructose-6-phosphate amidotransferase-1 (GFAT1) mRNA is selectively expressed in striated muscle. | 2001 Nov |
1 |
| 47 |
11930630 | [Phenotypic and functional alterations of mesangial cells in patients with diabetic nephropathy]. | 2001 Nov 25 |
2 |
| 48 |
10806197 | Phosphorylation of human glutamine:fructose-6-phosphate amidotransferase by cAMP-dependent protein kinase at serine 205 blocks the enzyme activity. | 2000 Jul 21 |
1 |
| 49 |
10997685 | Role of the hexosamine biosynthetic pathway in diabetic nephropathy. | 2000 Sep |
1 |
| 50 |
10997922 | Overexpression of GFAT activates PAI-1 promoter in mesangial cells. | 2000 Oct |
3 |