Probenecid

ATP binding cassette subfamily C member 1 ; Homo sapiens







47 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34990712 ABCC1 modulates negative feedback control of the hypothalamic-pituitary-adrenal axis in vivo in humans. 2022 Mar 2
2 33029084 Metformin reverses the drug resistance of cisplatin in irradiated CNE-1 human nasopharyngeal carcinoma cells through PECAM-1 mediated MRPs down-regulation. 2020 1
3 27926506 Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. 2017 Jan 10 1
4 27901486 Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition. 2016 Dec 27 1
5 26373208 Carrier-mediated placental transport of cimetidine and valproic acid across differentiating JEG-3 cell layers. 2015 Jul 2
6 23945567 Cellular uptake and antiproliferative effects of 11-oxo-eicosatetraenoic acid. 2013 Nov 1
7 24199578 [Study on transport mechanism of baicalin in Scutellariae radix extracts and effect of Angelica dahurica extracts on transport of baicalin by Caco-2 cell monolayer model]. 2013 Jul 1
8 21205825 Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation. 2011 Mar 4 1
9 21271607 Intestinal transport of bis(12)-hupyridone in Caco-2 cells and its improved permeability by the surfactant Brij-35. 2011 Apr 1
10 21458432 The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase. 2011 Jul 15 1
11 21804948 Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination. 2011 Feb 2 1
12 16621244 Schisandrin B: a dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1. 2007 Feb 8 1
13 17374608 Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. 2007 May 11 1
14 17430634 Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells. 2007 Apr 1
15 17710652 Flow cytometric monitoring of multidrug drug resistance protein 1 (MRP1/ABCC1) -mediated transport of 2',7'-bis-(3-carboxypropyl)-5-(and-6)- carboxyfluorescein (BCPCF) into human erythrocyte membrane inside-out vesicles. 2007 Sep-Dec 1
16 16447232 Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance-associated protein 1 and provokes high levels of cross-resistance to glucocorticoids. 2006 Feb 2
17 16679408 Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1. 2006 May 16 1
18 15585369 Mercury induces multidrug resistance-associated protein gene through p38 mitogen-activated protein kinase. 2005 Jan 15 1
19 16249698 Role of lymphocyte multidrug resistance protein 1 in HIV infection: expression, function, and consequences of inhibition. 2005 Nov 1 3
20 15120939 Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines. 2004 Jun 2
21 12486126 Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells. 2003 Feb 28 1
22 12686569 ATP released from astrocytes during swelling activates chloride channels. 2003 Apr 2
23 14581376 Multidrug-resistant tumor cells remain sensitive to a recombinant interleukin-4-Pseudomonas exotoxin, except when overexpressing the multidrug resistance protein MRP1. 2003 Oct 15 2
24 14655754 P-glycoprotein and multidrug resistance-associated protein mediate specific patterns of multidrug resistance in malignant glioma cell lines, but not in primary glioma cells. 2003 Oct 1
25 11864633 Budesonide reduces multidrug resistance-associated protein 1 expression in an airway epithelial cell line (Calu-1). 2002 Feb 15 1
26 11880368 Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). 2002 May 10 1
27 12115804 Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin. 2002 Aug 1
28 12218384 The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1). 2002 Sep 6 1
29 12373300 Dehydrothyrsiferol does not modulate multidrug resistance-associated protein 1 resistance: a functional screening system for MRP1 substrates. 2002 Nov 1
30 12454976 Single-cell image analysis to assess ABC-transporter-mediated efflux in highly purified hematopoietic progenitors. 2002 Dec 1 1
31 11178967 Down-regulation of catalase gene expression in the doxorubicin-resistant AML subline AML-2/DX100. 2001 Feb 16 1
32 11233999 Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood. 2001 Feb 2 1
33 11288109 P-glycoprotein efflux pump expression and activity in Calu-3 cells. 2001 May 1
34 11322768 Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid. 2001 Apr 27 12
35 11389878 Influences of glutathione on anionic substrate efflux in tumour cells expressing the multidrug resistance-associated protein, MRP1. 2001 Jul 15 1
36 11504821 Multidrug resistance-associated protein-1 functional activity in Calu-3 cells. 2001 Sep 1
37 11587213 Functional characterization of minimal residual disease for P-glycoprotein and multidrug resistance protein activity in acute myeloid leukemia. 2001 Oct 1
38 11595715 Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums. 2001 Oct 1
39 10727523 Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. 2000 Apr 1
40 11118294 Multidrug resistance P-glycoprotein is not involved in cholesterol esterification. 2000 Dec 20 1
41 10064732 Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1. 1999 Mar 1
42 10363967 Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. 1999 Jun 1 1
43 10404077 Adult T-cell leukemia cells over-express the multidrug-resistance-protein (MRP) and lung-resistance-protein (LRP) genes. 1999 Aug 12 1
44 10419897 Simultaneous activity of MRP1 and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia. 1999 Aug 1 1
45 9182837 Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells. 1997 3
46 8636432 Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. 1996 Mar 1 1
47 7628644 ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion. 1995 Jul 17 1