Glutathione

ATP binding cassette subfamily C member 1 ; Homo sapiens







241 Article(s)
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101 16114987 MRP-1 protein expression and glutathione content of in vitro tumor cell lines derived from human glioma carcinoma U-87-MG do not interact with 99mTc-glucarate uptake. 2005 Aug 3
102 16136554 Effects of new 4-aryl-1,4-dihydropyridines and 4-arylpyridines on drug efflux mediated by multidrug resistance-associated protein 1. 2005 Oct 1
103 16399362 Multidrug resistance protein 1-mediated export of glutathione and glutathione disulfide from brain astrocytes. 2005 1
104 14643890 Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione. 2004 Feb 4
105 14754409 Drug binding domains of MRP1 (ABCC1) as revealed by photoaffinity labeling. 2004 Jan 3
106 14757231 Fluorescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1. 2004 Jan 28 1
107 14979731 Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2). 2004 Mar 2 2
108 15006547 Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP- binding cassette (ABC) drug transporters. 2004 Mar 15 3
109 15041478 Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells. 2004 Apr 15 2
110 15161912 Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required. 2004 Jul 30 9
111 15298732 Docetaxel enhances the cytotoxicity of cisplatin to gastric cancer cells by modification of intracellular platinum metabolism. 2004 Aug 2
112 15473893 N-acetylcysteine enhances multidrug resistance-associated protein 1 mediated doxorubicin resistance. 2004 Oct 2
113 15498506 Relation between the ability of some compounds to modulate the MRP1-mediated efflux of glutathione and to inhibit the MRPl-mediated efflux of daunorubicin. 2004 Dec 1 3
114 15501592 Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain. 2004 6
115 15581632 Mistargeted MRPdeltaF728 mutant is rescued by intracellular GSH. 2004 Dec 3 1
116 12523936 Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). 2003 Apr 15 1
117 12532374 Effect of flavonoids on MRP1-mediated transport in Panc-1 cells. 2003 Feb 1
118 12623128 Kinetic analysis of fluorescein and dihydrofluorescein effluxes in tumour cells expressing the multidrug resistance protein, MRP1. 2003 Mar 15 4
119 12641460 Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17. 2003 Mar 25 16
120 12731885 Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. 2003 May 13 2
121 12897433 Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate. 2003 1
122 12944313 Kinetic analysis of rhodamines efflux mediated by the multidrug resistance protein (MRP1). 2003 Sep 1
123 12964004 Enhanced cytotoxicity and nuclear accumulation of doxorubicin-loaded nanospheres in human breast cancer MCF7 cells expressing MRP1. 2003 Oct 2
124 14578045 ATP and GSH dependence of MRP1-mediated outward translocation of phospholipid analogs in the human erythrocyte membrane. 2003 Oct-Dec 5
125 14629827 The multidrug resistance of in vitro tumor cell lines derived from human breast carcinoma MCF-7 does not influence pentavalent technetium-99m-dimercaptosuccinic Acid uptake. 2003 Oct 4
126 18365053 Resistance to arsenic- and antimony-based drugs. 2003 1
127 11880368 Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). 2002 May 10 1
128 12017298 MRP1 modulation by PAK-104P: detection with technetium-99m-MIBI in cultured lung tumor cells. 2002 Jan-Feb 1
129 12018890 The MRP1-mediated effluxes of arsenic and antimony do not require arsenic-glutathione and antimony-glutathione complex formation. 2002 Apr 2
130 12034727 GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. 2002 Aug 9 1
131 12090736 Chemosensitization of solid tumors by modulation of resistance mechanisms. 2002 Apr 1
132 12135486 S-decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1). 2002 Jul 1
133 12138119 Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione. 2002 Sep 20 3
134 12175932 Hypochlorous acid inhibits glutathione S-conjugate export from human erythrocytes. 2002 Aug 31 1
135 12186871 Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. 2002 Nov 1 3
136 12387749 Chronic arsenic-exposed human prostate epithelial cells exhibit stable arsenic tolerance: mechanistic implications of altered cellular glutathione and glutathione S-transferase. 2002 Sep 1 1
137 12487151 Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance. 2002 Nov 1
138 11301332 Glutathione-dependent binding of a photoaffinity analog of agosterol A to the C-terminal half of human multidrug resistance protein. 2001 Jun 22 7
139 11306701 Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. 2001 May 2
140 11331074 Resistance of human multidrug resistance-associated protein 1-overexpressing lung tumor cells to the anticancer drug arsenic trioxide. 2001 Jun 1 1
141 11389878 Influences of glutathione on anionic substrate efflux in tumour cells expressing the multidrug resistance-associated protein, MRP1. 2001 Jul 15 6
142 11391629 Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function. 2001 Jul 1 2
143 11408043 Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells. 2001 Jun 1 5
144 11444977 Functional expression of multidrug resistance protein 1 in Pichia pastoris. 2001 Jul 27 1
145 11448450 Verapamil-stimulated glutathione transport by the multidrug resistance-associated protein (MRP1) in leukaemia cells. 2001 Aug 15 14
146 11454692 Resistance to mitoxantrone in multidrug-resistant MCF7 breast cancer cells: evaluation of mitoxantrone transport and the role of multidrug resistance protein family proteins. 2001 Jul 15 3
147 11514236 Energy-dependent export of the 13-oxooctadecadienoic acid-glutathione conjugate from HT-29 cells and plasma membrane vesicles. 2001 Aug 29 2
148 11543717 Antiproliferative prostaglandins and the MRP/GS-X pump role in cancer immunosuppression and insight into new strategies in cancer gene therapy. 2001 Oct 1 1
149 11804191 MRP subfamily transporters and resistance to anticancer agents. 2001 Dec 1
150 10697038 Ifosfamide-based drug combinations: preclinical evaluation of drug interactions and translation into the clinic. 2000 Feb 4