Glutathione

ATP binding cassette subfamily C member 1 ; Homo sapiens







241 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 21918036 Monomethylarsenic diglutathione transport by the human multidrug resistance protein 1 (MRP1/ABCC1). 2011 Dec 3
52 21968975 Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells. 2011 7
53 19894120 Lipopolysaccharide increases the expression of multidrug resistance-associated protein 1 (MRP1) in RAW 264.7 macrophages. 2010 Dec 2
54 20204475 Catch me if you can! Novel aspects of cadmium transport in mammalian cells. 2010 Oct 1
55 20332504 Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2. 2010 May 28 3
56 18786560 Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology. 2009 Feb-Apr 6
57 19326901 Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells. 2009 May 1
58 19358561 Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma. 2009 May 19 1
59 19397308 Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments. 2009 Nov-Dec 1
60 19921956 Reactivity of 6-halopurine analogs with glutathione as a radiotracer for assessing function of multidrug resistance-associated protein 1. 2009 Nov 26 3
61 19946134 ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily. 2009 Dec 2
62 18079363 Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites. 2008 Mar 9
63 18204073 Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane. 2008 Apr 2
64 18281520 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1-mediated MDR in small cell lung cancer. 2008 Feb 1
65 18313196 Structure-activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2. 2008 Apr 18 1
66 18556457 Elevated GSH level increases cadmium resistance through down-regulation of Sp1-dependent expression of the cadmium transporter ZIP8. 2008 Sep 2
67 18621020 Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release. 2008 Oct 13
68 18691054 Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development. 2008 2
69 18768387 Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport. 2008 Dec 22
70 18775981 Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3). 2008 Dec 8
71 21479453 2,2'-Dihydroxychalcone, a glutathione transferase inhibitor, sensitises human colon adenocarcinoma cells to chlorambucil and melphalan, but not to actinomycin D. 2008 Jul-Aug 1
72 17329911 Genetic variations and haplotype structures of the ABC transporter gene ABCC1 in a Japanese population. 2007 Feb 25 3
73 17352253 Modulatory effects of heparin on cellular accumulation and cytotoxicity of doxorubicin in MRP1-overexpressing HL60/doxo cells. 2007 Jan-Feb 2
74 17359940 Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress. 2007 Jun 1 7
75 17374608 Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. 2007 May 11 7
76 17453352 Modulation of multidrug resistance protein (MRP1/ABCC1) expression: a novel physiological role for ouabain. 2007 Nov 2
77 17518506 Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy. 2007 2
78 17585883 Harnessing drug resistance: using ABC transporter proteins to target cancer cells. 2007 Dec 15 1
79 17646169 (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. 2007 Oct 26 4
80 17720877 Cigarette smoke irreversibly modifies glutathione in airway epithelial cells. 2007 Nov 2
81 16337611 Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling. 2006 Jan 12 1
82 16374597 Non-destructive micromethod for MRP1 functional assay in human lung tumor cells. 2006 Mar 4
83 16386247 On the putative co-transport of drugs by multidrug resistance proteins. 2006 Feb 13 6
84 16434618 Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux. 2006 Apr 1
85 16565074 Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1). 2006 May 19 15
86 16679408 Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1. 2006 May 16 6
87 16857677 SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis. 2006 Oct 6 2
88 17159804 Content of protein carbonyl groups in gerbil brain after reversible bilateral carotid occlusion: effect of 2,3-dihydromelatonin. 2006 Dec 1
89 15579473 GSH inhibits trypsinization of the C-terminal half of human MRP1. 2005 Feb 18 9
90 15628876 The leucotriene C4 binding sites in multidrug resistance protein 1 (ABCC1) include the first membrane multiple spanning domain. 2005 Jan 11 4
91 15652236 Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas. 2005 Feb 1 4
92 15737336 Nucleotide dissociation from NBD1 promotes solute transport by MRP1. 2005 Mar 1 1
93 15766272 Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1. 2005 Mar 22 3
94 15845416 Molecular mechanisms of reduced glutathione transport: role of the MRP/CFTR/ABCC and OATP/SLC21A families of membrane proteins. 2005 May 1 4
95 15960885 6-Hydroxydopamine-induced glutathione alteration occurs via glutathione enzyme system in primary cultured astrocytes. 2005 Jul 1
96 15989470 Study of monoglutathionyl conjugates TC-99M-sestamibi and TC-99M-tetrofosmin transport mediated by the multidrug resistance-associated protein isoform 1 in glioma cells. 2005 Jun 5
97 16004972 Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes. 2005 Aug 15 2
98 16037312 Transglycation--a potential new mechanism for deglycation of Schiff's bases. 2005 Jun 1
99 16041243 Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1). 2005 Sep 1
100 16042792 Multidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine sulfoximine. 2005 Jul 24 2