Glutathione

ATP binding cassette subfamily C member 1 ; Homo sapiens







241 Article(s)
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1 35080351 GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators. 2022 Jan 26 2
2 32954502 Noradrenaline protects neurons against H2 O2 -induced death by increasing the supply of glutathione from astrocytes via β3 -adrenoceptor stimulation. 2021 Feb 1
3 33609514 S-(+)-Pentedrone and R-(+)-methylone as the most oxidative and cytotoxic enantiomers to dopaminergic SH-SY5Y cells: Role of MRP1 and P-gp in cathinones enantioselectivity. 2021 Apr 1 2
4 33770183 Glutathione-coordinated metal complexes as substrates for cellular transporters. 2021 Apr 30 1
5 33880814 A multidrug resistance-associated protein inhibitor is a potential enhancer of the benzyl isothiocyanate-induced apoptosis induction in human colorectal cancer cells. 2021 Jul 1
6 34581579 Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins. 2021 Nov 19 1
7 32377003 Molecular analysis of the massive GSH transport mechanism mediated by the human Multidrug Resistant Protein 1/ABCC1. 2020 May 6 1
8 32855883 Characterisation of Glutathione Export from Human Donor Lenses. 2020 Jul 1
9 32915249 In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta. 2020 Nov 7
10 33100008 Theoretical Insights into the Cotransport Mechanism of GSH with Anticancer Drugs by MRP1. 2020 Nov 5 3
11 33190481 Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux. 2020 Nov 25 3
12 30537107 A high-throughput glutathione trapping assay with combined high sensitivity and specificity in high-resolution mass spectrometry by applying product ion extraction and data-dependent neutral loss. 2019 Feb 1
13 30941807 The A-B-C of small-molecule ABC transport protein modulators: From inhibition to activation-a case study of multidrug resistance-associated protein 1 (ABCC1). 2019 Nov 2
14 31268744 Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1). 2019 Oct 4
15 32055360 Exploring cysteine regulation in cancer cell survival with a highly specific "Lock and Key" fluorescent probe for cysteine. 2019 Nov 21 1
16 29233614 Monoterpene indole alkaloid azine derivatives as MDR reversal agents. 2018 Jan 15 1
17 29459276 Cytotoxicity of η6-areneruthenium-based molecules to glioblastoma cells and their recognition by multidrug ABC transporters. 2018 Mar 25 2
18 27984000 Flavonoid dimers are highly potent killers of multidrug resistant cancer cells overexpressing MRP1. 2017 Jan 15 3
19 28273561 Ferrocene-embedded flavonoids targeting the Achilles heel of multidrug-resistant cancer cells through collateral sensitivity. 2017 Apr 21 2
20 28695498 FMISO accumulation in tumor is dependent on glutathione conjugation capacity in addition to hypoxic state. 2017 Oct 1
21 28807879 Apigenin-induced ABCC1-mediated efflux of glutathione from mature erythrocytes inhibits the proliferation of Plasmodium falciparum. 2017 Nov 3
22 29299132 Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters. 2017 Dec 15 1
23 26563124 Covert hepatic encephalopathy: elevated total glutathione and absence of brain water content changes. 2016 Jun 2
24 26740192 Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters. 2016 Jan 18 2
25 27110363 The photochemical thiol-ene reaction as a versatile method for the synthesis of glutathione S-conjugates targeting the bacterial potassium efflux system Kef. 2016 Apr 29 2
26 27293991 MiR-135a and MRP1 play pivotal roles in the selective lethality of phenethyl isothiocyanate to malignant glioma cells. 2016 1
27 28276667 Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion. 2016 Mar 2
28 24524999 Short time exposure to hydrogen peroxide induces sustained glutathione export from cultured neurons. 2014 May 2
29 24601535 Understanding the structural requirements for activators of the Kef bacterial potassium efflux system. 2014 Apr 1 1
30 22824382 Efflux of glutathione and glutathione complexes from human erythrocytes in response to vanadate. 2013 Jan 1
31 23383265 Protection against oxidative stress in beta thalassemia/hemoglobin E erythrocytes by inhibitors of glutathione efflux transporters. 2013 3
32 23669236 Modulation of glutathione intracellular levels alters the spontaneous proliferation of lymphocyte from HTLV-1 infected patients. 2013 Sep 4
33 24013781 Nuclear multidrug-resistance related protein 1 contributes to multidrug-resistance of mucoepidermoid carcinoma mainly via regulating multidrug-resistance protein 1: a human mucoepidermoid carcinoma cells model and Spearman's rank correlation analysis. 2013 3
34 24080162 Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1. 2013 Dec 1
35 24312054 ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity. 2013 6
36 21856323 Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione. 2012 Jan 1 1
37 21964344 Mechanisms of glutathione disulfide efflux from erythrocytes. 2012 Jan 1 1
38 22054034 Dynamic monitoring of metal oxide nanoparticle toxicity by label free impedance sensing. 2012 Jan 13 1
39 22084240 Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes. 2012 Jan 2 2
40 22098952 Multidrug resistance associated proteins in multidrug resistance. 2012 Feb 1
41 22197475 Arsenic-glutathione conjugate transport by the human multidrug resistance proteins (MRPs/ABCCs). 2012 Mar 2
42 22293538 The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. 2012 Apr 3
43 22679290 Inhibition of the MRP1-mediated transport of the menadione-glutathione conjugate (thiodione) in HeLa cells as studied by SECM. 2012 Jul 17 2
44 22890881 Efflux of glutathione and glutathione complexes from human erythrocytes in response to inorganic arsenic exposure. 2012 Dec 1
45 22964495 Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells. 2012 Dec 2
46 21103974 Multidrug resistance proteins (MRPs, ABCCs): importance for pathophysiology and drug therapy. 2011 1
47 21166805 Formaldehyde stimulates Mrp1-mediated glutathione deprivation of cultured astrocytes. 2011 Feb 1
48 21558001 Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes. 2011 Nov 1
49 21620781 Assessing multidrug resistance protein 1-mediated function in cancer cell multidrug resistance by scanning electrochemical microscopy and flow cytometry. 2011 Aug 4
50 21728338 Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells. 2011 Aug 15 5