Verapamil

ATP binding cassette subfamily C member 1 ; Homo sapiens







36 Article(s)
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1 29459276 Cytotoxicity of η6-areneruthenium-based molecules to glioblastoma cells and their recognition by multidrug ABC transporters. 2018 Mar 25 1
2 30351934 Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry". 2018 Nov 21 1
3 27926506 Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. 2017 Jan 10 1
4 29299132 Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters. 2017 Dec 15 1
5 24231527 Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells. 2014 Mar 1
6 24558228 Characterization of ABC transporters in human skin. 2014 2
7 23229154 Mechanisms of verapamil-enhanced chemosensitivity of gallbladder cancer cells to platinum drugs: glutathione reduction and MRP1 downregulation. 2013 Feb 2
8 20563580 Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells. 2011 Apr 2
9 21804948 Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination. 2011 Feb 2 1
10 21968975 Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells. 2011 2
11 20441926 The synthesis and characterization of cellular membrane affinity chromatography columns for the study of human multidrug resistant proteins MRP1, MRP2 and human breast cancer resistant protein BCRP using membranes obtained from Spodoptera frugiperda (Sf9) insect cells. 2010 Jun 15 1
12 19397308 Formation and efflux of ATP-binding cassette transporter substrate 2,4-dinitrophenyl-S-glutathione from cultured human term placental villous tissue fragments. 2009 Nov-Dec 1
13 18535159 MRP (ABCC) transporters-mediated efflux of anti-HIV drugs, saquinavir and zidovudine, from human endothelial cells. 2008 Sep 1
14 18690712 Multidrug transport by the ABC transporter Sav1866 from Staphylococcus aureus. 2008 Sep 2 1
15 18768387 Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport. 2008 Dec 1
16 17359940 Modulation of GSH levels in ABCC1 expressing tumor cells triggers apoptosis through oxidative stress. 2007 Jun 1 2
17 17646169 (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. 2007 Oct 26 4
18 17710652 Flow cytometric monitoring of multidrug drug resistance protein 1 (MRP1/ABCC1) -mediated transport of 2',7'-bis-(3-carboxypropyl)-5-(and-6)- carboxyfluorescein (BCPCF) into human erythrocyte membrane inside-out vesicles. 2007 Sep-Dec 1
19 15628876 The leucotriene C4 binding sites in multidrug resistance protein 1 (ABCC1) include the first membrane multiple spanning domain. 2005 Jan 11 1
20 14757231 Fluorescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1. 2004 Jan 28 1
21 15044619 Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects. 2004 Apr 2
22 15167518 Limitations of (99m)Tc tetrofosmin in assessing reversal effects of verapamil on the function of multi-drug resistance associated protein 1. 2004 Jun 2
23 15256468 Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1. 2004 Jul 15 1
24 12641460 Binding of a photoaffinity analogue of glutathione to MRP1 (ABCC1) within two cytoplasmic regions (L0 and L1) as well as transmembrane domains 10-11 and 16-17. 2003 Mar 25 1
25 11864633 Budesonide reduces multidrug resistance-associated protein 1 expression in an airway epithelial cell line (Calu-1). 2002 Feb 15 1
26 12454976 Single-cell image analysis to assess ABC-transporter-mediated efflux in highly purified hematopoietic progenitors. 2002 Dec 1 1
27 11351295 Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance. 2001 Jun 15 2
28 11448450 Verapamil-stimulated glutathione transport by the multidrug resistance-associated protein (MRP1) in leukaemia cells. 2001 Aug 15 4
29 10973801 Structure-activity studies of verapamil analogs that modulate transport of leukotriene C(4) and reduced glutathione by multidrug resistance protein MRP1. 2000 Sep 7 4
30 10482990 Idarubicin DNA intercalation is reduced by MRP1 and not Pgp. 1999 Sep 1
31 9809975 BAX expression is associated with enhanced intracellular accumulation of paclitaxel: a novel role for BAX during chemotherapy-induced cell death. 1998 Nov 1 1
32 8909298 ATP-dependent transport of lipophilic cytotoxic drugs by membrane vesicles prepared from MRP-overexpressing HL60/ADR cells. 1996 Nov 5 1
33 8913319 Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells. 1996 Aug 1
34 7601572 MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: alterations in cellular pharmacokinetics and in pattern of cross-resistance. 1995 Jul 4 2
35 7640227 Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1. 1995 Aug 3
36 7954421 Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. 1994 Nov 15 1