Doxorubicin

ATP binding cassette subfamily C member 1 ; Homo sapiens







171 Article(s)
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101 16263302 Synthesis and biological evaluation of a series of flavone derivatives as potential radioligands for imaging the multidrug resistance-associated protein 1 (ABCC1/MRP1). 2006 Mar 1 1
102 16410038 Reversal of drug resistance in P-glycoprotein-expressing T-cell acute lymphoblastic CEM leukemia cells by copper N-(2-hydroxy acetophenone) glycinate and oxalyl bis (N-phenyl) hydroxamic acid. 2006 Nov 28 1
103 15880572 Doxorubicin induces expression of multidrug resistance-associated protein 1 in human small cell lung cancer cell lines by the c-jun N-terminal kinase pathway. 2005 Oct 20 8
104 15942634 The role of bioreductive activation of doxorubicin in cytotoxic activity against leukaemia HL60-sensitive cell line and its multidrug-resistant sublines. 2005 Jul 11 3
105 15946544 [Reversal effect of haloperidol on doxorubicin resistance and chloride channel inhibition in erythroleukemic cell K562/Dox]. 2005 Feb 1
106 16170027 Cyclooxygenase-independent down-regulation of multidrug resistance-associated protein-1 expression by celecoxib in human lung cancer cells. 2005 Sep 2
107 16202586 Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1). 2005 Dec 15 1
108 15006547 Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP- binding cassette (ABC) drug transporters. 2004 Mar 15 1
109 15152944 Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer. 2004 Mar-Apr 4
110 15198509 Development and characterization of a recombinant Madin-Darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRP1). 2004 Mar 9 2
111 15233869 Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line. 2004 Jul 9
112 15473893 N-acetylcysteine enhances multidrug resistance-associated protein 1 mediated doxorubicin resistance. 2004 Oct 5
113 12576456 RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response. 2003 Feb 1
114 12632060 Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76. 2003 Apr 1
115 12632074 Reversal of drug resistance mediated by hammerhead ribozyme against multidrug resistance-associated protein 1 in a human glioma cell line. 2003 Apr 1
116 12647018 Modulation of multidrug resistance-associated protein 1 (MRP1) by p53 mutant in Saos-2 cells. 2003 Feb 1
117 12799644 Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines. 2003 Jun 16 1
118 12964004 Enhanced cytotoxicity and nuclear accumulation of doxorubicin-loaded nanospheres in human breast cancer MCF7 cells expressing MRP1. 2003 Oct 1
119 14620511 Sensitization of cells overexpressing multidrug-resistant proteins by pluronic P85. 2003 Oct 1
120 14655754 P-glycoprotein and multidrug resistance-associated protein mediate specific patterns of multidrug resistance in malignant glioma cell lines, but not in primary glioma cells. 2003 Oct 1
121 11920626 Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin. 2002 Apr 1 2
122 11958985 Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1). 2002 Mar 25 1
123 12042670 A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance. 2002 Jun 2
124 12085207 Expression of multidrug resistance-associated protein1,P-glycoprotein, and thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection. 2002 May 20 2
125 12088114 Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells. 2002 May 1
126 11178967 Down-regulation of catalase gene expression in the doxorubicin-resistant AML subline AML-2/DX100. 2001 Feb 16 2
127 11278000 Nucleotide-induced conformational changes in the human multidrug resistance protein MRP1 are related to the capacity of chemotherapeutic drugs to accumulate or not in resistant cells. 2001 Mar 23 1
128 11322768 Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid. 2001 Apr 27 1
129 11351295 Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance. 2001 Jun 15 4
130 11408511 Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin. 2001 Jun 15 1
131 11410522 Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. 2001 Jun 2
132 10821682 The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites. 2000 May 23 1
133 11112520 Rhodamine 123 binds to multiple sites in the multidrug resistance protein (MRP1). 2000 Dec 19 1
134 9923448 Selectively induced high MRP gene expression in multidrug-resistant human HL60 leukemia cells. 1999 Jan 2
135 10049760 Direct interaction between a quinoline derivative, MS-209, and multidrug resistance protein (MRP) in human gastric cancer cells. 1999 Feb 24 1
136 10100721 Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response. 1999 Mar 1
137 10200335 GSH, GSH-related enzymes and GS-X pump in relation to sensitivity of human tumor cell lines to chlorambucil and adriamycin. 1999 May 3
138 10428874 Localization of a substrate specificity domain in the multidrug resistance protein. 1999 Aug 6 2
139 10556489 ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells. 1999 Nov 9 1
140 10612603 Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146. 1999 Dec 6 1
141 9443942 Kinetics of anthracycline efflux from multidrug resistance protein-expressing cancer cells compared with P-glycoprotein-expressing cancer cells. 1998 Jan 1
142 9485370 Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein. 1998 Feb 24 2
143 9647783 Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump. 1998 Jun 29 8
144 9679555 Coordinate changes in expression of protective genes in drug-resistant cells. 1998 Apr 24 1
145 9683290 Lack of a role for MRP1 in platinum drug resistance in human ovarian cancer cell lines. 1998 Jul 1
146 9713512 Co-transfection of MDR1 and MRP antisense RNAs abolishes the drug resistance in multidrug-resistant human lung cancer cells. 1998 Jul-Aug 2
147 9763226 S9788 modulation of P-glycoprotein- and Multidrug-related protein-mediated multidrug resistance by Servier 9788 in doxorubicin-resistant MCF7 cells. 1998 Aug 15 1
148 9835508 Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters. 1998 Dec 1
149 9849488 Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs). 1998 Jul 1
150 9073310 Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP. 1997 Feb 1